LOCUS AF342982 3501 bp mRNA linear HUM 18-SEP-2001
DEFINITION Homo sapiens tankyrase 2 mRNA, complete cds.
ACCESSION AF342982
VERSION AF342982.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3501)
AUTHORS Kaminker,P.G., Kim,S.H., Taylor,R.D., Zebarjadian,Y., Funk,W.D.,
Morin,G.B., Yaswen,P. and Campisi,J.
TITLE TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes
rapid induction of cell death upon overexpression
JOURNAL J. Biol. Chem. 276 (38), 35891-35899 (2001)
PUBMED 11454873
REFERENCE 2 (bases 1 to 3501)
AUTHORS Kaminker,P.G., Campisi,J., Kim,S.H., Yaswen,P. and Morin,G.
TITLE Direct Submission
JOURNAL Submitted (25-JAN-2001) Life Sciences, Lawrence Berkeley National
Labs, 1 Cyclotron Rd 84-171, Berkeley, CA 94720, USA
FEATURES Location/Qualifiers
source 1..3501
/db_xref="H-InvDB:HIT000077998"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q23-q24"
CDS 1..3501
/note="TNKS2; telomere-associated poly(ADP-ribose)
polymerase; contains ankyrin domain, sterile alpha motif
and PARP catalytic domain; similar to TNKS"
/codon_start=1
/product="tankyrase 2"
/protein_id="AAK25811.1"
/translation="MSGRRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLV
TPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFG
HAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTA
LDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLA
AGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLW
QFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHS
LLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGAN
INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCR
LLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETV
KKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNA
CSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD
GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTP
LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA
TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM
PPSALPSCYKPQVLNGVRSPGATADALSSGPSSPSSLSAASSLDNLSGSFSELSSVVS
SSGTEGASSLEKKEVPGVDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKE
IGINAYGHRHKLIKGVERLISGQQGLNPYLTLNTSGSGTILIDLSPDDKEFQSVEEEM
QSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLF
HGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRS
CYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQ
AYPEYLITYQIMRPEGMVDG"
BASE COUNT 1044 a 707 c 840 g 909 t
ORIGIN
1 atgtcgggtc gccgctgcgc cggcggggga gcggcctgcg cgagcgccgc ggccgaggcc
61 gtggagccgg ccgcccgaga gctgttcgag gcgtgccgca acggggacgt ggaacgagtc
121 aagaggctgg tgacgcctga gaaggtgaac agccgcgaca cggcgggcag gaaatccacc
181 ccgctgcact tcgccgcagg ttttgggcgg aaagacgtag ttgaatattt gcttcagaat
241 ggtgcaaatg tccaagcacg tgatgatggg ggccttattc ctcttcataa tgcatgctct
301 tttggtcatg ctgaagtagt caatctcctt ttgcgacatg gtgcagaccc caatgctcga
361 gataattgga attatactcc tctccatgaa gctgcaatta aaggaaagat tgatgtttgc
421 attgtgctgt tacagcatgg agctgagcca accatccgaa atacagatgg aaggacagca
481 ttggatttag cagatccatc tgccaaagca gtgcttactg gtgaatataa gaaagatgaa
541 ctcttagaaa gtgccaggag tggcaatgaa gaaaaaatga tggctctact cacaccatta
601 aatgtcaact gccacgcaag tgatggcaga aagtcaactc cattacattt ggcagcagga
661 tataacagag taaagattgt acagctgtta ctgcaacatg gagctgatgt ccatgctaaa
721 gataaaggtg atctggtacc attacacaat gcctgttctt atggtcatta tgaagtaact
781 gaacttttgg tcaagcatgg tgcctgtgta aatgcaatgg acttgtggca attcactcct
841 cttcatgagg cagcttctaa gaacagggtt gaagtatgtt ctcttctctt aagttatggt
901 gcagacccaa cactgctcaa ttgtcacaat aaaagtgcta tagacttggc tcccacacca
961 cagttaaaag aaagattagc atatgaattt aaaggccact cgttgctgca agctgcacga
1021 gaagctgatg ttactcgaat caaaaaacat ctctctctgg aaatggtgaa tttcaagcat
1081 cctcaaacac atgaaacagc attgcattgt gctgctgcat ctccatatcc caaaagaaag
1141 caaatatgtg aactgttgct aagaaaagga gcaaacatca atgaaaagac taaagaattc
1201 ttgactcctc tgcacgtggc atctgagaaa gctcataatg atgttgttga agtagtggtg
1261 aaacatgaag caaaggttaa tgctctggat aatcttggtc agacttctct acacagagct
1321 gcatattgtg gtcatctaca aacctgccgc ctactcctga gctatgggtg tgatcctaac
1381 attatatccc ttcagggctt tactgcttta cagatgggaa atgaaaatgt acagcaactc
1441 ctccaagagg gtatctcatt aggtaattca gaggcagaca gacaattgct ggaagctgca
1501 aaggctggag atgtcgaaac tgtaaaaaaa ctgtgtactg ttcagagtgt caactgcaga
1561 gacattgaag ggcgtcagtc tacaccactt cattttgcag ctgggtataa cagagtgtcc
1621 gtggtggaat atctgctaca gcatggagct gatgtgcatg ctaaagataa aggaggcctt
1681 gtacctttgc acaatgcatg ttcttatgga cattatgaag ttgcagaact tcttgttaaa
1741 catggagcag tagttaatgt agctgattta tggaaattta cacctttaca tgaagcagca
1801 gcaaaaggaa aatatgaaat ttgcaaactt ctgctccagc atggtgcaga ccctacaaaa
1861 aaaaacaggg atggaaatac tcctttggat cttgttaaag atggagatac agatattcaa
1921 gatctgctta ggggagatgc agctttgcta gatgctgcca agaagggttg tttagccaga
1981 gtgaagaagt tgtcttctcc tgataatgta aattgccgcg atacccaagg cagacattca
2041 acacctttac atttagcagc tggttataat aatttagaag ttgcagagta tttgttacaa
2101 cacggagctg atgtgaatgc ccaagacaaa ggaggactta ttcctttaca taatgcagca
2161 tcttacgggc atgtagatgt agcagctcta ctaataaagt ataatgcatg tgtcaatgcc
2221 acggacaaat gggctttcac acctttgcac gaagcagccc aaaagggacg aacacagctt
2281 tgtgctttgt tgctagccca tggagctgac ccgactctta aaaatcagga aggacaaaca
2341 cctttagatt tagtttcagc ggatgatgtc agcgctcttc tgacagcagc catgccccca
2401 tctgctctgc cctcttgtta caagcctcaa gtgctcaatg gtgtgagaag cccaggagcc
2461 actgcagatg ctctctcttc aggtccatct agcccatcaa gcctttctgc agccagcagt
2521 cttgacaact tatctgggag tttttcagaa ctgtcttcag tagttagttc aagtggaaca
2581 gagggtgctt ccagtttgga gaaaaaggag gttccaggag tagattttag cataactcaa
2641 ttcgtaagga atcttggact tgagcaccta atggatatat ttgagagaga acagatcact
2701 ttggatgtat tagttgagat ggggcacaag gagctgaagg agattggwat caatgcttat
2761 ggacataggc acaaactaat taaaggagtc gagagactta tctccggaca acaaggtctt
2821 aacccatatt taactttgaa cacctctggt agtggaacaa ttcttataga tctgtctcct
2881 gatgataaag agtttcagtc tgtggaggaa gagatgcaaa gtacagttcg agagcacaga
2941 gatggaggtc atgcaggtgg aatcttcaac agatacaata ttctcaagat tcagaaggtt
3001 tgtaacaaga aactatggga aagatacact caccggagaa aagaagtttc tgaagaaaac
3061 cacaaccatg ccaatgaacg aatgctattt catgggtctc cttttgtgaa tgcaattatc
3121 cacaaaggct ttgatgaaag gcatgcgtac ataggtggta tgtttggagc tggcatttat
3181 tttgctgaaa actcttccaa aagcaatcaa tatgtatatg gaattggagg aggtactggg
3241 tgtccagttc acaaagacag atcttgttac atttgccaca ggcagctgct cttttgccgg
3301 gtaaccttgg gaaagtcttt cctgcagttc agtgcaatga aaatggcaca ttctcctcca
3361 ggtcatcact cagtcactgg taggcccagt gtaaatggcc tagcattagc tgaatatgtt
3421 atttacagag gagaacaggc ttatcctgag tatttaatta cttaccagat tatgaggcct
3481 gaaggtatgg tcgatggata a
//