LOCUS AF340151 4676 bp mRNA linear HUM 17-APR-2001
DEFINITION Homo sapiens fovea-associated SH3 domain binding protein (FASH3)
mRNA, complete cds.
ACCESSION AF340151
VERSION AF340151.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4676)
AUTHORS Bowes Rickman,C., Yarovinsky,T.O., McKay,B.S., Stone,E.M.,
Ritter,R., Rickman,D.W. and Edwards,A.O.
TITLE Characterization of a Novel Candidate Gene, FASH3, Expressed in the
Primate Fovea and Linked to the Disease Gene, ELOVL4, Associated
with Stargardt-like Dominant Progressive Macular Dystrophy
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4676)
AUTHORS Bowes Rickman,C. and Yarovinsky,T.O.
TITLE Direct Submission
JOURNAL Submitted (24-JAN-2001) Ophthalmology and Cell Biology, Duke
University, Box 3802 DUMC, Durham, NC 27710, USA
FEATURES Location/Qualifiers
source 1..4676
/db_xref="H-InvDB:HIT000077992"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q14"
gene 1..4676
/gene="FASH3"
CDS 180..503
/gene="FASH3"
/note="expressed in retina; highly similar to SH3BGRL: SH3
domain binding glutamic acid-rich protein-like"
/codon_start=1
/product="fovea-associated SH3 domain binding protein"
/protein_id="AAK37526.1"
/translation="MVIRVFIASSSGFVAIKKKQQDVVRFLEANKIEFEEVDITMSEE
QRQWMYKNVPPEKKPTQGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLKPRLA
SKAEP"
BASE COUNT 1392 a 866 c 960 g 1458 t
ORIGIN
1 ccgggcggcg ctgggctttt atctgcggac ccgccgggag ggagccagat cccagcgatc
61 ttccccgacg gcagcgcttt acccagaggc tgccggcggc tcgtagctgg gttcagctct
121 gcgtccacgc cagcccggag cccggggggc aaggggtctg tcccgggcgc agcgagagga
181 tggtcatccg cgtgttcatc gcctcttcct cgggcttcgt ggcgataaag aagaagcagc
241 aagatgtggt tagatttctg gaagccaaca agatagagtt tgaggaggtg gatatcacaa
301 tgtcagaaga acagaggcaa tggatgtaca aaaacgtccc cccggaaaag aaacccactc
361 agggcaaccc cctgccacct cagatattta atggcgaccg atactgtgga gattatgaca
421 gtttttttga atccaaggaa agcaacacag tcttttcatt tttaggcctg aaaccacggt
481 tggcatcaaa ggcagaacct tagagaagaa gagtggaaga tgacggagat gcattttgaa
541 gcacccctgg tactcagcac acacatgctt acctaatgca tcactgtgac aaaagccaca
601 cgcattatca gtaactttgc ttgccacgga aaaggtgttt ttgaaagatg tggctataat
661 gagaattgca tgattgcttt aaaccaaatc aggtggtgga tttttttttt cttattctat
721 ttgcctgcag ttgcctcact cacctggaaa taccgtcacc tgttacaggt gtactttctt
781 aatgactgaa agataagtgg gtagcaccgt cagagagaaa atgttggatc tgccctaggt
841 tatagtagat gccggaattg cgtaaaccca cttctcttta agctgcctgg attgcacctt
901 tgaaatatgt ctgccaagtt gttagaatct ttgaatcaga aggaaaaaaa gcagcgctgg
961 ttgacaaagg gtgttgaaga tttttgctgc agaatcagtt acaaacatca cagttcccat
1021 gctttgtaat aacacctggt gaaaaagtta gatattctag acttgtttta gtaatggaaa
1081 ctcttacctc cacatattat cttacagatg tttccagaaa tccctgttgt aacatcaagt
1141 gatcagaact aagttactgg gatgacaata attgctattt gaaatatatg cttctttatt
1201 tcttgcaagg ggcaagtttc acccaaatgc ctgagactgc ttgaaagata tattttaagt
1261 ggtgcactaa ttagtgaata tataggaaaa ttatctgacg agtatctgaa ggcattttca
1321 gctctagcaa tttatttata atatataagt tcatatattt tttaatccag ctcccctaac
1381 agacagctgc tgcttctatt ttgtgaaggg actatatttt ttgagaaagg aaaatctcag
1441 ttagatatat tttgtgaacc cttgattaga catattaaaa tataccaatg ttgtagtaaa
1501 atttaatttt tccttttgtt acttttcatt tgcctctaat tttgcttgct catatttctg
1561 gccaatgtac agcctcatat ttttcagagt aatacagata cttgttctca ttccgtatat
1621 gagcacaagt aaggtttcag agcaacacac atgagaaaga gagtaacccg gaattgtact
1681 tgtcaagcaa aatctatact cctattggag tggatgctga tgaacatcga acatatctac
1741 ttcattagag cagaggctat ttttctgcat tcttgtccct ataacaggga tgcttaattt
1801 tttttttaac ttagagtttt aaattgccaa acatgggaac agccttgaat aggataaatt
1861 ttcagagggc tgcctaaaat attttatttc tagcatcctg attctggact tttcattata
1921 attctgagca ggaaatttat aagaaattga aagagcagaa gaattacagc cctgtcacat
1981 gtgcccagca ctccgcccca tgccttgcta aatgtagact aaagaacttg ttgaatgcta
2041 aggctgaaat cccaacctga gatttgtagt ccaggattac aaccagaagg aaagtatgac
2101 agatttctac ttaactagaa tggacacatg atccacaatt ttctcttcag gggaagctgt
2161 tgtcaaatta tggatattac tggttagttg tcattaagta agatccaggt caaattccat
2221 ttgacaaatc ccagggacta tccaggaatt tttttttaac tggatattgt gtttgagtat
2281 gtgagtcttc tgataaaact cagaatttct ttttaagcag ttgtaaaaat tgtcatgttg
2341 taattcatta ctcagctaac atttagtcta ctcttgctag tgagtgccaa gaaccaactt
2401 ggtaaggttg aggctttgca agttaactgc tggggttata ggatcaatac catacttgct
2461 agacaaagct acccagattt gtcttatatt ataatttttg agttaaccgt agtataccta
2521 ttatgattat agtaaacaga ctagtgggta gtaatgctaa attaccatca cagttatgtg
2581 ccatctcccc accccatttt tttttttttt tttttgatca gcaaagaaat acaggagacc
2641 agtctcgagt ggtgctgtac ttgttatgag tggggcagca gcacagtgtg tggcatttac
2701 atggtaccca ggctccacag agtaccaaga tgttgccctc tgggaccaca cttagctcag
2761 agaatatggg gtccttactt gtattctgtt atcagctgat tttgaaacat ataataatga
2821 ttttcttgtt cccttcttta actagctgcc tttagatttt gataatcaca gtcttaaaat
2881 actaggaaag aagtggatgg gaattgtagg catagatttc atatcaaggg catttcaaga
2941 cagaattttt atttcctgta gtaggcttgc tggagcaaag gaaatgtgct gctaaaaatc
3001 aacttatgcc attttaaaat tagataaaat atggagtgcc atcctgctag gtgagtacag
3061 accagaagaa aatttagttg ggaaaatact tgtttttcca aattccggtg ttttattaca
3121 atcaaagaag aggaaagcaa ggtatttttt cacctcagat tctaatatat tctagatttg
3181 tttctgtttt atagatttaa ttcaatacct ccacatagat gtttttatat tacatgaatt
3241 taataataaa ctaaactttt ttttgtctcc cgttattgaa aagtaccaaa gcttctttct
3301 gttgtgtttg attttactat aggggttttg ctttttctag agatactttt catttaacag
3361 cttttgttaa gtgtcaggct gcactttgct ccatataatt attgttttca gatttcaact
3421 tgtatgtgtt tgtctcttaa agcattggtg aaatcacata ttttatattc agcataaagg
3481 agaataaatt ccagaaaaca catattctga aaatggagtg tttgttccct gccatttttc
3541 acacctctct taattttagt tctgtttagt tgagaggctg tgattttact cttgcctgtg
3601 aacctcatgc atgaaagcag cacattaaat tgtaaaaata caaacagatc gtgtgatcat
3661 tcaaggagcc agacatgagg tcctgcacga gggtgttggg aggacaccac agattcatct
3721 cagacagtga tcaggactga ggatggagtt aaatcactca gcccctgggt ggggtggggt
3781 ggttcaaatg gatgactgat ctcctgagta cactgaagcc acaggctggt ggccatgttc
3841 tctgaattgg gtgcagaaga caagggcaga gtggctgcgg cccctattac ctttgtagca
3901 gccacatcag aaagcagaag aaaacagtat ttctgaaggc attgtttgag gttgatctca
3961 gcactgaacg atttcaagcc ctacgcacca gaacagaagg agggtggagg aagtgatcag
4021 agggaacgag ctgtaggttt gcagaaatgt gtgaaaccaa aatgatcact gcctacttgt
4081 gattcaaatc ttcagagttt tcctagttct tctagaaata catgtcaggt ttgtttgttc
4141 atcctttctg tcagcatgga tcaagcccct aaaatgtggt aagtgttgtc agagcagggc
4201 aatatctcta ctctcaagta tgaggggaat agaaacaaag cagcagtttt agccagggtt
4261 caatgataga gtggaggtaa attaagagcc tccaggctgt gattcaccat ttgagacatt
4321 atacataatt tgtttttgtt ataagccatt tgaattttta aaaaatttca tacatgcaat
4381 ggaatataga tatgtatata cacatataat atatatgcta aagtataaag agtaataata
4441 atgacaataa acaaacccct gtgtgcctac cacccacctt attgcctttc ctttgaggta
4501 ccgtgtgcgg tttcctgaac ctatctctat ccctgtctga tagagggaac ccctgtactg
4561 aactttgtgt tgaccatagc cttcttgtct ttcatcactt tatctccatg tatgtatcct
4621 taaagaataa taaatggaat taaactcaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//