LOCUS AF336981 2784 bp mRNA linear HUM 01-OCT-2001
DEFINITION Homo sapiens neprilysin-like metallopeptidase 2 mRNA, complete cds.
ACCESSION AF336981
VERSION AF336981.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2784)
AUTHORS Bonvouloir,N., Lemieux,N., Crine,P., Boileau,G. and
DesGroseillers,L.
TITLE Molecular cloning, tissue distribution, and chromosomal
localization of MMEL2, a gene coding for a novel human member of
the neutral endopeptidase-24.11 family
JOURNAL DNA Cell Biol. 20 (8), 493-498 (2001)
PUBMED 11560781
REFERENCE 2 (bases 1 to 2784)
AUTHORS Bonvouloir,N., Lemieux,N., Crine,P., Boileau,G. and
DesGroseillers,L.
TITLE Direct Submission
JOURNAL Submitted (15-JAN-2001) Biochemistry, University of Montreal, P. O.
Box 6128, Station Centre Ville, Montreal, Quebec H3C 3J7, Canada
FEATURES Location/Qualifiers
source 1..2784
/db_xref="H-InvDB:HIT000077853"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36"
CDS 65..2377
/note="NEP-like 2; zinc metallopeptidase"
/codon_start=1
/product="neprilysin-like metallopeptidase 2"
/protein_id="AAL08942.1"
/translation="MVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGK
QLPRLASRLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEP
CDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKAR
TLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQF
NRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVA
TLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQ
FGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVW
RLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREA
FPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEE
MNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFY
SPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMM
DWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGGVRQAYKAY
LKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVL
GSLQNLAAFADTFHCARGTPMHPKERCRVW"
BASE COUNT 669 a 789 c 841 g 485 t
ORIGIN
1 aaaggttcct gcggtgctct cccgtccaga gccctgctga tggggaagtc cgaaggccgt
61 ggggatggtg gagagcgccg gccgtgcagg gcagaagcgc ccggggttcc tggagggggg
121 gctgctgctg ctgctgctgc tggtgaccgc tgccctggtg gccttgggtg tcctctacgc
181 cgaccgcaga gggaagcagc tgccacgcct tgctagccgg ctgtgcttct tacaggagga
241 gaggaccttt gtaaaacgaa aaccccgagg gatcccagag gcccaagagg tgagcgaggt
301 ctgcaccacc cctggctgcg tgatagcagc cgccaggatc ctccagaaca tggacccgac
361 cacggaaccg tgtgacgact tctaccagtt tgcatgcgga ggctggctgc ggcgccacgt
421 gatccctgag accaactcaa gatacagcat ctttgacgtc ctccgcgacg agctggaggt
481 catcctcaaa gcggtgctgg agaattcgac tgccaaggac cggccggctg tggagaaggc
541 caggacgctg taccgctcct gcatgaacca gagtgtgata gagaagcgag gctctcagcc
601 cctgctggac atcttggagg tggtgggagg ctggccggtg gcgatggaca ggtggaacga
661 gaccgtagga ctcgagtggg agctggagcg gcagctggcg ctgatgaact cacagttcaa
721 caggcgcgtc ctcatcgacc tcttcatctg gaacgacgac cagaactcca gccggcacat
781 catctacata gaccagccca ccttgggcat gccctcccga gagtactact tcaacggcgg
841 cagcaaccgg aaggtgcggg aagcctacct gcagttcatg gtgtcagtgg ccacgttgct
901 gcgggaggat gcaaacctgc ccagggacag ctgcctggtg caggaggaca tggtgcaggt
961 tctggagctg gagacacagc tggccaaggc cacggtaccc caggaggaga gacacgacgt
1021 catcgccttg taccaccgga tgggactgga ggagctgcaa agccagtttg gcctgaaggg
1081 atttaactgg actctgttca tacaaactgt gctatcctct gtcaaaatca agctgctgcc
1141 agatgaggaa gtggtggtct atggcatccc ctacctgcag aaccttgaaa acatcatcga
1201 cacctactca gccaggacca tacagaacta cctggtctgg cgcctggtgc tggaccgcat
1261 tggtagccta agccagagat tcaaggacac acgagtgaac taccgcaagg cgctgtttgg
1321 cacaatggtg gaggaggtgc gctggcgtga atgtgtgggc tacgtcaaca gcaacatgga
1381 gaacgccgtg ggctccctct acgtcaggga ggcgttccct ggagacagca agagcatggt
1441 cagagaactc attgacaagg tgcggacagt gtttgtggag acgctggacg agctgggctg
1501 gatggacgag gagtccaaga agaaggcgca ggagaaggcc atgagcatcc gggagcagat
1561 cgggcaccct gactacatcc tggaggagat gaacaggcgc ctggacgagg agtactccaa
1621 tctgaacttc tcagaggacc tgtactttga gaacagtctg cagaacctca aggtgggcgc
1681 ccagcggagc ctcaggaagc ttcgggaaaa ggtggaccca aatctctgga tcatcggggc
1741 ggcggtggtc aatgcgttct actccccaaa ccgaaaccag attgtattcc ctgccgggat
1801 cctccagccc cccttcttca gcaaggagca gccacaggcc ttgaactttg gaggcattgg
1861 gatggtgatc gggcacgaga tcacgcacgg ctttgacgac aatggccgga acttcgacaa
1921 gaatggcaac atgatggatt ggtggagtaa cttctccacc cagcacttcc gggagcagtc
1981 agagtgcatg atctaccagt acggcaacta ctcctgggac ctggcagacg aacagaacgt
2041 gaacggattc aacacccttg gggaaaacat tgctgacaac ggaggggtgc ggcaagccta
2101 taaggcctac ctcaagtgga tggcagaggg tggcaaggac cagcagctgc ccggcctgga
2161 tctcacccat gagcagctct tcttcatcaa ctatgcccag gtgtggtgcg ggtcctaccg
2221 gcccgagttc gccatccaat ccatcaagac agacgtccac agtcccctga agtacagggt
2281 actggggtcg ctgcagaacc tggccgcctt cgcagacacg ttccactgtg cccggggcac
2341 ccccatgcac cccaaggagc gatgccgcgt gtggtagcca aggccctgcc gcgctgtgcg
2401 gcccacgccc acccgctgct cggaggcatc tgtgcgaagg tgcagctagc ggcgacccag
2461 tgtacgtccc gccccggcca accatgccaa gcctgcctgc caggcctctg cgcctggcct
2521 agggtgcagc cacctgcctg acacccaggg atgagcagtg tccagtgcag tacctggacc
2581 ggagccccct tcacagacac ccgcggggct cagtgccccc gtcacaactc tgtagagaca
2641 atcaactgtg tcctgcccac ccttcaaggt gcattgtctt ccagtatcta cagcttcaga
2701 acttgagcta agtaaatgct ttcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaa
//