LOCUS AF336304 1897 bp mRNA linear HUM 12-MAY-2001
DEFINITION Homo sapiens macroH2A2 mRNA, complete cds.
ACCESSION AF336304
VERSION AF336304.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1897)
AUTHORS Chadwick,B.P. and Willard,H.F.
TITLE Histone H2A variants and the inactive X chromosome: identification
of a second macroH2A variant
JOURNAL Hum. Mol. Genet. 10 (10), 1101-1113 (2001)
PUBMED 11331621
REFERENCE 2 (bases 1 to 1897)
AUTHORS Chadwick,B.P. and Willard,H.F.
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2001) Genetics, Case Western Reserve University,
2109 Adelbert Road, BRB 701, Cleveland, OH 44106, USA
FEATURES Location/Qualifiers
source 1..1897
/db_xref="H-InvDB:HIT000077830"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q22.3"
CDS 192..1310
/note="H2A-variant; enriched in inactive X chromosome
chromatin"
/codon_start=1
/product="macroH2A2"
/protein_id="AAK52471.1"
/translation="MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVG
APVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIAS
GGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKATSGKKGGKKSKAAKPRTSKKS
KPKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHP
TTAEIDLKEDIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHC
HIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAI
SAHFDDSSASSLKNVYFLLFDSESIGIYVQEMAKLDAK"
BASE COUNT 521 a 480 c 519 g 377 t
ORIGIN
1 tgacacgcac agatagaacc caaagaaagg caaagagtcc tgcccggcac cggcgccgcg
61 tgggccaaac ctgcgcccgt ggaggggcgc gcagagggca ccgggcgccg ggagcaggcg
121 gcgcagcacc agcattgtgt tagtgccggg aggccactgt gtcagcaagc tgagagggaa
181 actgaagcaa gatgtcgggc cggagtggga agaagaaaat gtccaagctg tcccgttcag
241 ctagggcagg tgtcatcttt ccagtgggga ggctgatgcg ttatctgaag aaagggacgt
301 tcaagtaccg gatcagcgtg ggcgcccctg tctacatggc ggcagtcatt gagtacctgg
361 cagcggaaat tctagaattg gccggcaatg ccgcgaggga caacaagaag gcccggatag
421 ccccgagaca catcttgctg gcagttgcca atgacgagga gctcaaccag ctgctaaaag
481 gagtgaccat cgccagtgga ggcgtcctgc ccagaattca ccccgaactg ctggccaaaa
541 agcgagggac caaaggcaag tcggaaacga tcctctcccc acccccagag aaaagaggca
601 ggaaggccac gtcaggcaag aaggggggga agaaatccaa ggctgccaaa ccacggacgt
661 ccaaaaagtc caaaccaaag gacagcgata aagaaggaac ttcaaattcc acctctgaag
721 atgggccagg ggatggattc accattctgt cttctaagag ccttgttctg ggacagaagc
781 tgtccttaac ccagagtgac atcagccata ttggctccat gagagtggag ggcattgtcc
841 acccaaccac agccgaaatt gacctcaaag aagatatagg taaagccttg gaaaaggctg
901 ggggaaaaga gttcttggaa acggtaaagg agcttcgcaa atcccaaggc cctttggaag
961 tcgccgaagc cgccgtcagc caatccagtg gactcgcagc caaatttgtc atccactgtc
1021 acatccctca gtggggctcc gacaaatgtg aagaacagct tgaagagacc atcaaaaact
1081 gcctgtcagc ggcggaggac aagaagctaa agtccgtcgc gttcccgcct ttccccagcg
1141 gcagaaactg ctttcccaaa cagactgcgg cccaggtgac cctcaaagcc atctcagccc
1201 actttgatga ctcgagcgcg tcctcgctga agaacgtgta cttcctgctc ttcgacagcg
1261 agagcatcgg catctacgtg caggagatgg ccaagctcga cgccaagtag ccgccgcact
1321 ttccagcagg gatcggagga cgacccgagt cccaagagtg gggttttgct ttttaaaagg
1381 agagaggagg ggtgatggca ggggagtgga gggtggccgg gcaggtcctg ccggcgcagg
1441 gagccctctg cccttcacac tctcctccaa aagagcctcc atctgtaagg aagcaggtct
1501 ccgcgagggg tttctttcca tgtgttttcc tcctgttgtt aaaagaactt ttttaaaaaa
1561 acagacctcg ttttagattt atagcattga cttttacaca cattcacaca agaaaaaaat
1621 cctttcaaaa ttcttaaatc ttctgttcct cctttttcca agggaagagg gcaaaaagtg
1681 gcctgggctc tgttggtgtg cgtgttccgt ggcggagaga agaaaatggg aaagacatct
1741 cactggtgct tttctctttt gttttagtgc cccccgcccc catccctata atatctgtaa
1801 ctactcctaa aaaggttttg attcaggctt ttttttggtt tcattttgtt tttttaagaa
1861 aaagaaaatg aaaggaaaaa aaaaaaaaaa aaaaaaa
//