LOCUS AF332473 1669 bp mRNA linear HUM 09-APR-2001
DEFINITION Homo sapiens GalNAc-4-sulfotransferase 2 mRNA, complete cds,
alternatively spliced.
ACCESSION AF332473
VERSION AF332473.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1669)
AUTHORS Kang,H.G., Evers,M.R., Xia,G., Baenziger,J.U. and Schachner,M.
TITLE Molecular cloning and expression of an
N-acetylgalactosamine-4-O-sulfotransferase that transfers sulfate
to terminal and non-terminal beta 1,4-linked N-acetylgalactosamine
JOURNAL J. Biol. Chem. 276 (14), 10861-10869 (2001)
PUBMED 11139592
REFERENCE 2 (bases 1 to 1669)
AUTHORS Kang,H.-G., Evers,M.R., Xia,G., Baenziger,J.U. and Schachner,M.
TITLE Direct Submission
JOURNAL Submitted (27-DEC-2000) Pathology, Washington University, 660 S.
Euclid Ave., St. Louis, MO 63130, USA
FEATURES Location/Qualifiers
source 1..1669
/db_xref="H-InvDB:HIT000077734"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q11.2"
CDS 113..1189
/function="transfers sulfate to internal beta1,4-linked
GalNAc in chondroitin and dermatan"
/note="GalNAc-4-O-sulfotransferase (Met86); alternatively
spliced; N-acetylgalactosamine-4-O-sulfotransferase-2;
GalNAc-4-ST2; does not contain a transmembrane domain;
does not transfer sulfate to terminal beta1,4-linked
GalNAc on N-linked oligosaccharides"
/codon_start=1
/product="GalNAc-4-sulfotransferase 2"
/protein_id="AAK30370.1"
/translation="MPEDVREKKENLLLNSERSTRLLTKTSHSQGGDQALSKSTGSPT
EKLIEKRQGAKTVFNKFSNMNWPVDIHPLNKSLVKDNKWKKTEETQEKRRSFLQEFCK
KYGGVSPPQSHLFHTVSRIYVEDKHKILYCEVPKAGCSNWKRILMVLNGLASSAYNIS
HNAVHYGKHLKKLDSFDLKGIYTRLNTYTKAVFVRDPMERLVSAFRDKFEHPNSYYHP
VFGKAIIKKYRPNACEEALINGSGVKFKEFIHYLLDSHRPVGMDIHWEKVSKLCYPCL
INYDFVGKFETLEEDANYFLQMIGAPKELKFPNFKDRHSSDERTNAQVVRQYLKDLTR
TERQLIYDFYYLDYLMFNYTTPFL"
BASE COUNT 563 a 295 c 331 g 480 t
ORIGIN
1 aagcttggca cgagggggag agtggagaag agaagagaac aaaaagtaac ttcaggatgg
61 ggaccagtga agtacttgcg gcctgtaccc agaatcaaac cccaagtttc acatgcctga
121 ggatgtacga gaaaaaaagg aaaatcttct actcaattct gagagatcta ctaggctctt
181 aacaaagacc agtcattcac aaggagggga tcaagcttta agtaagtcca cagggtcacc
241 aacagagaag ttgattgaaa aacgtcaagg agctaagact gtttttaaca agttcagcaa
301 catgaattgg ccagtggaca ttcacccttt aaacaaaagt ttagtcaaag ataataaatg
361 gaagaaaact gaggagaccc aagagaaacg aaggtctttc cttcaggagt tttgcaagaa
421 atacggtggg gtgagtcctc ctcagtcaca tctttttcat acagtatcca gaatctatgt
481 agaagataaa cacaaaatct tatattgtga ggtacctaag gctggctgtt ccaattggaa
541 aagaattctg atggtactaa atggattggc ttcctctgca tacaacatct cccacaatgc
601 tgtccactac gggaagcatt tgaagaagct agatagcttt gacctaaaag ggatatatac
661 ccgcttaaat acttacacca aagctgtgtt tgttcgtgat cccatggaaa gattagtatc
721 agcctttagg gacaaatttg aacaccccaa tagttattac catccagtat tcggaaaggc
781 aattatcaag aaatatcgac caaatgcctg tgaagaagca ttaattaatg gatctggagt
841 caagttcaaa gagtttatcc actacttgct ggattcccac cgtccagtag gaatggacat
901 tcactgggaa aaggtcagca aactctgcta tccgtgtttg atcaactatg attttgtagg
961 gaaatttgag actttggaag aagatgccaa ttacttttta cagatgatcg gtgctccaaa
1021 ggagctgaaa tttcccaact ttaaggatag gcactcttcc gatgaaagaa ccaatgctca
1081 agtcgtgaga cagtatttaa aggatctgac tagaactgag agacaattaa tctatgactt
1141 ttattacttg gactatttaa tgtttaatta tacaactcca tttttgtagt ttgcattcat
1201 tttctaaaac cctgtatata cttaatgatg ataagttcaa atcagctgta atttttctat
1261 aattctctgt atgacagaaa tttaaccaag tgcagttgtc ttgatttaat gtagattttt
1321 accaaatagt atgacaccaa ttggcacaaa gttataggaa aatcacctac aggagatgta
1381 aacaacttga gttgctctaa aatgtttgga aaagagctgc ttttgcatta tgaattatat
1441 tgttgaagca ataacctagc cagctgttgc attagctaaa gcagcctctt gcaatggtag
1501 gaaaaaagga tctcaaatag catgagtgta tgtctatatc ctgaaattta ttgtctaaaa
1561 tgcatgaata tatttttagc agtctgtggc atattaatca aactgttgaa ttgttttctt
1621 acaccctgga aatctttcta tcaactataa tgataaatcc attttgaag
//