LOCUS AF331520 3786 bp mRNA linear HUM 02-JUL-2001
DEFINITION Homo sapiens ubiquitin-fusion degradation protein 2 mRNA, complete
cds.
ACCESSION AF331520
VERSION AF331520.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3786)
AUTHORS Mahoney,J.A., Odin,J.A., Shaffer,D., Koff,A., Casciola-Rosen,L. and
Rosen,A.
TITLE A human homolog of yeast UFD2p is cleaved by caspase 6 and granzyme
B during apoptosis
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3786)
AUTHORS Mahoney,J.A., Odin,J.A., Casciola-Rosen,L. and Rosen,A.
TITLE Direct Submission
JOURNAL Submitted (21-DEC-2000) Medicine, Johns Hopkins University School
of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..3786
/db_xref="H-InvDB:HIT000077666"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36"
/cell_line="HeLa"
CDS 48..3569
/note="UFD2; possible splice variant compared to sequence
encoded by GenBank Accession Number AF043117"
/codon_start=1
/product="ubiquitin-fusion degradation protein 2"
/protein_id="AAK69622.1"
/translation="MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAA
SAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSR
SQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQ
LVCKIFRVSWKDRDRDVIFLSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRD
ENPFASLTATSQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGG
ASNWDSYSDHFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQ
CISHTALVLQGSLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFI
PILQGLALAAKECSLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSP
GCGRELQRLSYLGAFFSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGR
QELFKILHSILLNGETREAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQ
QLSTKIKLETVDPTYIFHPRCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKF
PTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHRE
MLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPL
NSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRN
PYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLSTKLLVPSLMKFYTDVEHTGATSE
FYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSGKQFVRYINMLINDTTFLLDESLE
SLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLALATETVDMFHILT
KQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDIY
LQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLAEKVEEIVAK
NARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDPFNRQTL
TESMLEPVPELKEQIQAWMREKQNSDH"
BASE COUNT 1019 a 964 c 897 g 906 t
ORIGIN
1 aacagaagga tctctcctta acgcctttca ccattaagag gaaagcgatg gaggagctga
61 gcgctgatga gattcgacgg aggcgccttg cacgacttgc tggtggacag acctctcagc
121 caaccacccc actcacctct ccccagaggg agaaccctcc ggggcctccc atagcggcat
181 cagccccagg accctctcag agtcttggtc tcaatgtcca caacatgacc ccagctacct
241 ccccaatagg tgcatcagga gtagcccatc gaagccagag cagtgaagga gtcagttctc
301 tcagcagctc gccctctaat agccttgaaa cgcaatctca gtctctctca cgttcccaga
361 gcatggatat cgatggtgtc tcatgtgaga aaagcatgtc ccaggtggat gtggattcag
421 gaattgaaaa catggaggtt gatgaaaatg atcgaagaga aaagcggagc ctcagtgata
481 aggagccttc ctcgggccct gaagtgtctg aagagcaggc cttacagctg gtctgtaaga
541 tcttccgtgt ctcttggaag gaccgggaca gagatgtcat ctttctttct tctctttctg
601 cacagtttaa gcagaaccca aaagaagtat tctccgattt taaggacttg attggccaga
661 ttttaatgga agtgctaatg atgtccactc agaccagaga tgaaaaccca tttgccagtc
721 tgacagccac atcacagcca attgctgcag cagcacggtc accagacaga aatctcttgc
781 taaacactgg ctccaatcca ggaacaagcc ccatgttctg cagcgtggct tcctttggtg
841 ccagctcttt gtctagtttg ggagcctctg gtggagcaag taattgggat tcctacagtg
901 accatttcac cattgaaacc tgcaaagaga cagatatgct gaactacctc atcgagtgtt
961 tcgaccgagt tggaatagag gaaaaaaaag caccaaagat gtgcagccag ccagcagtca
1021 gccagcttct gagcaacatc cgctcacagt gcatatccca tactgcttta gtactacaag
1081 gctccctaac acagcccagg tccttgcagc agccgtcctt cctagtgccg tatatgctgt
1141 gtaggaatct cccatatggc ttcattcagg aactggtgag aaccactcac caggatgaag
1201 aagtgttcaa gcagatattt atccccattt tacaaggcct ggctcttgct gccaaagagt
1261 gctccctcga cagtgactac tttaaatacc ccctcatggc actaggtgag ctctgtgaaa
1321 ccaagtttgg gaagacacac cctgtgtgca atttggttgc ttctttgcgg ttgtggttgc
1381 cgaaatcctt aagtcctggc tgtgggcggg agctgcagag actctcttac ttaggggctt
1441 tctttagctt ctcagtcttt gcagaagatg atgttaaagt ggttgaaaaa tacttctcag
1501 ggcctgccat taccctggaa aacactcgtg tggttagcca atcattgcag cattacttag
1561 agctcggaag gcaagagctt tttaagattc tgcatagtat tttgttaaat ggcgaaaccc
1621 gtgaggctgc tctcagttac atggcggctg tcgtcaatgc caatatgaag aaagcacaga
1681 tgcagacaga tgatagattg gtgtctacag atggatttat gctgaatttc ctttgggtac
1741 tgcagcagct aagtacaaaa atcaagttag aaacagttga tcccacgtat atttttcacc
1801 caagatgtcg gattactctt cccaatgatg agacgcgtgt gaatgcaacg atggaagatg
1861 tgaatgactg gctgactgaa ctctatggcg atcagcctcc attttctgag ccgaaattcc
1921 ctacggagtg cttctttctc accctgcatg ctcaccacct ctctattctg cctagttgcc
1981 gtcgctatat ccgcagactc cgggctatcc gggagctcaa tagaactgta gaagatttga
2041 aaaataatga aagccaatgg aaagattccc cactggcaac tagacaccgc gaaatgctga
2101 agcgctgtaa aactcagctt aagaaactgg tacggtgcaa ggcctgtgct gatgctggcc
2161 tacttgacga gagcttcctg agaagatgtc tgaattttta tggccttctc attcagctgc
2221 tgctccgcat cctggacccc gcatatcccg atataacact gcctttaaat tcagatgtcc
2281 ccaaggtatt tgcagcgttg cctgagtttt atgtagaaga tgttgcagaa tttttatttt
2341 ttattgtaca atactctccc caggcgcttt atgagccctg tactcaggat attgtgatgt
2401 tccttgttgt gatgttgtgc aaccagaact acatccgaaa cccatatttg gtggccaaac
2461 tggtagaagt catgtttatg accaaccctg ctgttcagcc acgaacccag aagttttttg
2521 aaatgattga gaaccatcct ctctccacca agttgttggt accttccctg atgaagttct
2581 atacagatgt tgagcatacc ggagccacca gcgagtttta tgacaagttc acaattcgct
2641 atcacattag caccattttt aaaagccttt ggcaaaacat agctcaccat ggcaccttta
2701 tggaggagtt caactccggg aagcagtttg ttcgctatat aaacatgttg ataaacgaca
2761 cgacgttttt gctcgatgaa agtctggagt ctctgaagcg aatccatgaa gtgcaggaag
2821 agatgaagaa caaagaacag tgggaccagt tgccccggga tcagcagcag gctcgtcagt
2881 ctcagcttgc tcaggatgag cgtgtgtccc gctcttacct cgccctggcc accgaaaccg
2941 tggacatgtt ccacatcctc acgaagcagg tccagaagcc cttcctcaga ccggagcttg
3001 gaccccgatt ggctgcaatg ctgaacttta atcttcagca actttgtggc cccaagtgcc
3061 gtgacctgaa agttgaaaac cctgagaaat acggctttga accaaagaag ctgttggacc
3121 aactgacgga tatttactta cagctggact gtgctcggtt cgcgaaagcc attgctgacg
3181 accagagatc ctacagtaag gaattgtttg aagaagttat ttcaaagatg cggaaggcag
3241 ggatcaaatc cacaatagca atagaaaaat ttaagctgct cgccgagaaa gtggaggaga
3301 tagtggccaa gaacgcacgc gcagaaatcg actacagcga cgctcctgat gagttcagag
3361 accctctgat ggacaccctc atgacagacc ccgtgcggct gccctctggc accatcatgg
3421 accgctccat catcctgcgg cacctgctca actcccccac ggaccccttc aaccggcaga
3481 cgctgacaga gagcatgctg gaaccagtgc cagaactgaa agagcagatt caggcgtgga
3541 tgagagagaa acagaacagc gatcactaaa ccgttccgcc gcccaccctc tgctagacac
3601 agccaaggcc aacgaggcaa gcagaagcag cggccgcagc gaagctgctg ttcatgtgtt
3661 ggaggccaaa tgtggcaaac caaccccagg cccacccaga gcgagcaaac gctgagacct
3721 gaaaggacat ggatgagaag aggagcccgc ttcctgtaca tatatttaag tgacaaacac
3781 ggtcaa
//