LOCUS AF331033 5085 bp mRNA linear HUM 13-AUG-2002
DEFINITION Homo sapiens AH-related protein mRNA, complete cds, alternatively
spliced.
ACCESSION AF331033
VERSION AF331033.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5085)
AUTHORS Reed,B.Y., Gitomer,W.L., Heller,H.J., Hsu,M.C., Lemke,M.,
Padalino,P. and Pak,C.Y.
TITLE Identification and characterization of a gene with base
substitutions associated with the absorptive hypercalciuria
phenotype and low spinal bone density
JOURNAL J. Clin. Endocrinol. Metab. 87 (4), 1476-1485 (2002)
PUBMED 11932268
REFERENCE 2 (bases 1 to 5085)
AUTHORS Reed,B.Y., Gitomer,W.L., Heller,H.J., Hsu,M., Lemke,M.,
Padalino,P.K. and Pak,C.Y.C.
TITLE Direct Submission
JOURNAL Submitted (21-DEC-2000) Center for Mineral Metabolism and Clinical
Research, UT Southwestern Medical Center at Dallas, 5323 Harry
Hines Blvd., Dallas, TX 75390-8885, USA
FEATURES Location/Qualifiers
source 1..5085
/db_xref="H-InvDB:HIT000077660"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24"
/tissue_type="intestine"
CDS 499..5055
/note="alternatively spliced at the 5' end of exon 5"
/codon_start=1
/product="AH-related protein"
/protein_id="AAL57036.1"
/translation="MSLSEGDALLALWRVERKQLKNIITVVIKCSLEIHGLFETQEWE
EGLDIRVKIGLAAGHISMLVFGDETHSHFLVIGQAVDDVRLAQNMAQMNDVILSPNCW
QLCDRSMIEIESVPDQRAVKVNFLKPPPNFNFDEFFTKCTTFMHYYPSGEHKNLLRLA
CTLKPDPELEMSLQKYVMESILKQIDNKQLQGYLSELRPVTIVFVNLMFEDQDKAEEI
GPAIQDAYMHITSVLKIFQGQINKVFMFDKGCSFLCVFGFPGEKVPDELTHALECAMD
IFDFCSQVHKIQTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNLAARMMMYYPGIVT
CDSVTYNGSNLPAYFFKELPKKVMKGVADSGPLYQYWGRTEKVMFGMACLICNRKEDY
PLLGRNKEINYFMYTMKKFLISNSSQVLMYEGLPGYGKSQILMKIEYLAQGKNHRIIA
ISLNKISFHQTFYTIQMFMANVLGLDTCKHYKERQTNLRNKVMTLLDEKFYCLLNDIF
HVQFPISREISRMSTLKKQKQLEILFMKILKLIVKEERIIFIIDEAQFVDSTSWRFME
KLIRTLPIFIIMSLCPFVNIPCAAARAVIKNRNTTYIVVGAVQPNDISNKICLDLNVS
CISKELDSYLGEGSCGIPFYCEELLKNLEHHEVLVFQQTESEEKTNRTWNNLFKYSIK
LTEKLNMVTLHSDKESEEVCHLTSGVRLKNLSPPTSLKEISLIQLDSMRLSHQMLVRC
AAIIGLTFTTELLFEILPCWNMKMMIKTLATLVESNIFYCFRNGKELQKALKQNDPSF
EVHYRSLSLKPSEGMDHGEEEQLRELENEVIECHRIRFCNPMMQKTAYELWLKDQRKA
MHLKCARFLEEDAHRCDHCRGRDFIPYHHFTVNIRLNALDMDAIKKMAMSHGFKTEEK
LILSNSEIPETSAFFPENRSPEEIREKILNFFDHVLTKMKTSDEDIIPLESCQCEEIL
EIVILPLAHHFLALGENDKALYYFLEIASAYLIFCDNYMAYMYLNEGQKLLKTLKKDK
SWSQTFESATFYSLKGEVCFNMGQIVLAKKMLRKALKLLNRIFPYNLISLFLHIHVEK
NRHFHYVNRQAQESPPPGKKRLAQLYRQTVCLSLLWRIYSYSYLFHCKYYAHLAVMMQ
MNTALETQNCFQIIKAYLDYSLYHHLAGYKGVWFKYEVMAMEHIFNLPLKGEGIEIVA
YVAETLVFNKLIMGHLDLAIELGSRALQMWALLQNPNRHYQSLCRLSRCLLLNSRYPQ
LIQVLGRLWELSVTQEHIFSKAFFYFVCLDILLYSGFVYRTFEECLEFIHQYENNRIL
KFHSGLLLGLYSSVAIWYARLQEWDNFYKFSNRAKNLLPRRTMTLTYYDGISRYMEGQ
VLHLQKQIKEQSENAQASGEELLKNLENLVAQNTTGPVFCPRLYHLMAYVCILMGDGQ
KCGLFLNTALRLSETQGNILEKCWLNMNKESWYSTSELKEDQWLQTILSLPSWEKIVA
GRVNIQDLQKNKFLMRANTVDNHF"
BASE COUNT 1479 a 1118 c 1126 g 1362 t
ORIGIN
1 gacagacatg gcgcttcagc tgtcttcaga ataatgtcac ccggcctcct ctcctgtctt
61 ctgcagtctt aaaagaccta gtccctaact gaggtctggc ttttcctcag ccctggatga
121 agtggagaag acctatttgg agactgcttc ctgtcaccat aaaatcctga acatttgtct
181 tgaacatgaa cactccaaaa gaagaattcc aggactggcc catagtcaga atagcagctc
241 atttaccaga cctcattgtc tatggacatt tctccccaga gcgacccttt atggattatt
301 ttgacggagt cctgatgttt gttgatattt caggttttac tgcaatgact gagaagttca
361 gcagtgccat gtacatggac agaggggctg agcagttggt ggagatcctc aactaccaca
421 taagtgcaat agtggagaaa gtgttgattt ttggaggaga catcctgaaa tttgcagggc
481 aggtcaaaag cccgcggcat gtctctctct gaaggtgatg cactgctagc cctgtggagg
541 gtggagcgaa agcagctgaa aaacattatc acagtggtaa ttaaatgtag cctggagatc
601 catggattgt ttgagaccca ggagtgggaa gaaggcctag acatccgagt caagatagga
661 ctggctgctg gccacatcag catgttggtc tttggagatg aaacacacag ccactttctg
721 gtgattggtc aggcagtgga cgatgtgcgc cttgcccaga acatggctca gatgaatgat
781 gttattctgt caccaaactg ctggcagctc tgtgaccgga gcatgattga aattgagagt
841 gttccagatc agagagcagt taaggttaac ttcttaaaac caccccccaa ttttaatttt
901 gatgaatttt tcacaaagtg tacgaccttc atgcattatt atccttctgg tgagcacaaa
961 aacctcctga ggcttgcatg cacgctgaag cctgatcctg aactggagat gtccctacaa
1021 aagtatgtga tggaaagcat tttgaagcag attgataaca aacagcttca gggctattta
1081 tctgagcttc gcccagtgac gattgtgttt gtgaacctga tgtttgaaga ccaagacaaa
1141 gcagaagaga taggcccagc catccaggat gcctatatgc acatcacttc tgtcctgaag
1201 atcttccaag gccaaatcaa taaagtcttc atgtttgaca agggctgctc tttcctctgt
1261 gtctttggct tccctgggga aaaggtacct gacgagctca ctcatgctct ggaatgtgct
1321 atggatatat ttgacttctg ctctcaagtc cacaaaatcc aaactgtatc catcggcgtt
1381 gccagtggga ttgtcttctg tgggatcgtt ggacacactg tgagacacga gtacacagtc
1441 attggtcaaa aagtcaactt agctgccagg atgatgatgt actacccagg aattgtgacc
1501 tgcgactctg tcacctacaa tgggagcaac ctaccagcgt acttttttaa agagcttcca
1561 aagaaagtta tgaaaggtgt tgcagattct ggaccattgt atcagtattg gggccgtact
1621 gagaaagtca tgtttggtat ggcgtgcctc atctgcaaca gaaaggagga ttaccctttg
1681 ctgggacgta ataaagagat caactacttc atgtatacta tgaagaaatt tttgatatct
1741 aacagcagcc aagtcttaat gtatgaggga ttaccaggat atggaaaaag ccagatactt
1801 atgaaaattg agtacctggc ccaaggtaag aatcacagga ttattgccat ttcattgaat
1861 aagatcagct tccatcaaac tttctatacc atccagatgt tcatggccaa tgtcctaggc
1921 ctagacactt gtaaacatta taaagaacga cagaccaacc ttcgaaataa agtcatgaca
1981 ctgttggatg aaaagttcta ctgtcttctt aatgacattt tccatgttca gttccctatt
2041 tctcgggaga tttccaggat gagcaccttg aaaaagcaaa aacaattgga aatattgttt
2101 atgaagatct tgaagctgat agtgaaagag gaaaggatta tttttatcat tgatgaggcc
2161 cagtttgtgg attcgacctc ctggagattc atggagaagc ttatccggac tcttcctatc
2221 ttcatcatta tgtccctgtg tcccttcgtt aacattccct gtgcagctgc cagggccgta
2281 ataaagaaca ggaacaccac ctacattgtc gttggtgcag tacagcctaa cgacatctcc
2341 aacaagatct gtcttgacct caatgtgagc tgcatctcca aagaactgga ctcgtacctg
2401 ggggagggaa gctgtgggat tccattttac tgtgaagaat tgcttaaaaa cctggaacat
2461 catgaggtac tcgttttcca acaaacggag tctgaggaaa agacaaatag gacctggaat
2521 aacctgttca agtattccat taagctaaca gagaagttaa acatggttac tctccatagt
2581 gataaggaaa gtgaagaagt ctgtcacctc acaagtggcg tcagactgaa aaacctgtca
2641 cctccaacgt cattaaaaga aatctctctg atccagctgg atagcatgag actttcccac
2701 caaatgctgg tgagatgtgc tgccatcatt ggcctgacct tcaccactga gttgttgttt
2761 gagattctcc cctgttggaa tatgaagatg atgatcaaga ccctggcaac cctagtggaa
2821 tctaacattt tttattgttt ccggaatggc aaggagcttc aaaaggccct gaaacagaat
2881 gatccctcat ttgaggtgca ctatcgttcc ttgtctctga agcccagtga agggatggat
2941 cacggtgaag aggaacagct tcgtgaactg gagaatgagg tgatcgagtg ccacaggatc
3001 cgattctgta accctatgat gcagaaaaca gcctacgagc tgtggctcaa ggaccagaga
3061 aaagccatgc acttgaaatg tgcccgcttt ttagaagaag atgcccacag atgtgaccac
3121 tgccgaggca gggacttcat tccctatcat cacttcacag tgaatattcg gctcaacgct
3181 ttagacatgg atgccattaa aaagatggct atgtctcatg gatttaaaac tgaagaaaag
3241 cttatcttgt ccaactcaga gattcctgag acatctgcat tttttcctga aaatcgcagt
3301 cctgaagaaa taagagaaaa gatcttgaat ttctttgacc acgttttaac aaaaatgaag
3361 acatctgacg aagacattat ccctctggaa tcttgccagt gtgaagaaat cctagagatt
3421 gtcatcttgc ctctggccca ccattttctg gctttgggag aaaatgacaa agccttatat
3481 tacttcttag aaattgcatc tgcttatctc atcttttgtg ataactacat ggcatacatg
3541 tatttgaatg aaggacagaa gttgctaaaa actctcaaga aggacaaatc ttggagccag
3601 acatttgagt ctgccacctt ttacagcctc aaaggtgagg tctgtttcaa tatgggccag
3661 atagtgcttg ccaagaaaat gctgaggaag gcactgaagc tcctcaaccg aatctttcct
3721 tacaacttaa tctccttgtt tctccatatc catgtcgaga aaaacagaca ctttcattat
3781 gtgaatcggc aggcccaaga gagcccacct ccagggaaga agaggctggc acaactttac
3841 cggcaaactg tctgcctttc cttgctgtgg cgcatctata gctacagtta tctttttcac
3901 tgcaagtatt atgcccacct ggcagttatg atgcaaatga atactgcact ggaaactcaa
3961 aattgtttcc agatcattaa ggcttaccta gactattcgc tataccacca cctggctggc
4021 tacaaaggtg tgtggttcaa atatgaagtc atggccatgg agcacatctt caacctcccc
4081 ctgaaaggcg agggcattga aatcgtggca tacgtggctg agacactggt cttcaacaag
4141 ctcataatgg gacacctgga tttggccatt gagttaggct cccgagccct tcagatgtgg
4201 gcactgctcc agaatcccaa ccgacattat cagtccctct gcagacttag cagatgtctc
4261 cttctgaaca gcagataccc gcaattgatc caggtgctgg ggcggctgtg ggagctttct
4321 gtaacacagg aacacatctt cagcaaggca tttttctatt ttgtctgctt ggacatcctg
4381 ctttattctg gttttgttta tagaacattt gaagaatgtt tggaattcat acaccaatac
4441 gaaaacaaca gaatcctcaa gttccacagt ggactcctcc tgggacttta ttcctctgta
4501 gctatctggt atgccagact tcaggaatgg gacaactttt acaaattttc caatagagct
4561 aaaaatcttt tgccaagaag aaccatgaca cttacttact atgacggaat atctaggtac
4621 atggaggggc aagttcttca ccttcaaaaa caaatcaaag aacagtcaga gaatgcccaa
4681 gccagtgggg aggagctact caagaacttg gagaatctgg tggctcaaaa taccactggc
4741 cctgtctttt gcccaaggct ctaccacctg atggcttacg tctgtatatt aatgggagat
4801 gggcagaaat gtggcctctt cctgaacaca gccttgcggc tctctgaaac acaggggaat
4861 atactggaga aatgctggct gaacatgaac aaagaatcat ggtactcaac ctctgagtta
4921 aaagaagacc aatggcttca gacgatcttg agtctcccat catgggaaaa aattgtagca
4981 ggcagggtaa acattcagga tcttcaaaaa aacaaattcc tgatgagagc taataccgtg
5041 gacaatcatt tctaacatgt caaagaaaaa agattttaat aagct
//