LOCUS AF328788 1896 bp mRNA linear HUM 08-NOV-2001
DEFINITION Homo sapiens amnionless mRNA, complete cds.
ACCESSION AF328788
VERSION AF328788.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1896)
AUTHORS Kalantry,S., Manning,S., Haub,O., Tomihara-Newberger,C., Lee,H.G.,
Fangman,J., Disteche,C.M., Manova,K. and Lacy,E.
TITLE The amnionless gene, essential for mouse gastrulation, encodes a
visceral-endoderm-specific protein with an extracellular
cysteine-rich domain
JOURNAL Nat. Genet. 27 (4), 412-416 (2001)
PUBMED 11279523
REFERENCE 2 (bases 1 to 1896)
AUTHORS Kalantry,S. and Lacy,E.
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2000) Program in Molecular Biology, Memorial
Sloan-Kettering Cancer Center, 1275 York Ave. RRL 937, New York, NY
10021, USA
FEATURES Location/Qualifiers
source 1..1896
/db_xref="H-InvDB:HIT000077575"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q32.3; 102 mb; between TRAF3 and CDC42BPB"
CDS 23..1384
/note="visceral endoderm-specific type 1 transmembrane
protein; AMN"
/codon_start=1
/product="amnionless"
/protein_id="AAK28532.1"
/translation="MGVLGRVLLWLQLCALTQAVSKLWVPNTDFDVAANWSQNRTPCA
GGAVEFPADKMVSVLVQEGHAVSDMLLPLDGELVLASGAGFGVSDVGSHLDCGAGEPA
VFRDSDRFSWHDPHLWRSGDEAPGLFFVDAERVPCRHDDVFFPPSASFRVGLGPGASP
VRVRSISALGRTFTRDEDLAVFLASRAGRLRFHGPGALSVGPEDCADPSGCVCGNAEA
QPWICAALLQPLGGRCPQAACHFALRPQGQCCDLCGAVVLLTHGPAFDLERYRARILD
TFLGLPQYHGLQVAVSKVPRSSRLREADTEIQVVLVENGPETGGAGRLARALLADVAE
NGEALGVLEATMRESGAHVWGSSAAGLAGGVAAAVLLALLVLLVAPPLLRRAGRLRWR
RHEAAAPAGAPLGFRNPVFDVTASEELPLPRRLSLVPKAAADSTSHSYFVNPLFAGAE
AEA"
misc_feature 635..781
/note="Region: extracellular cysteine-rich domain"
misc_feature 1097..1159
/note="Region: transmembrane domain"
BASE COUNT 247 a 644 c 692 g 313 t
ORIGIN
1 gggtgcaagg agccgaggcg agatgggcgt cctgggccgg gtcctgctgt ggctgcagct
61 ctgcgcactg acccaggcgg tctccaaact ctgggtcccc aacacggact tcgacgtcgc
121 agccaactgg agccagaacc ggaccccgtg cgccggcggc gccgttgagt tcccggcgga
181 caagatggtg tcagtcctgg tgcaagaagg tcacgccgtc tcagacatgc tcctgccgct
241 ggatggggaa ctcgtcctgg cttcaggagc cggattcggc gtctcagacg tgggctcgca
301 cctggactgt ggcgcgggcg aacctgccgt cttccgcgac tctgaccgct tctcctggca
361 tgacccgcac ctgtggcgct ctggggacga ggcacctggc ctcttcttcg tggacgccga
421 gcgcgtgccc tgccgccacg acgacgtctt ctttccgcct agtgcctcct tccgcgtggg
481 gctcggccct ggcgctagcc ccgtgcgtgt ccgcagcatc tcggctctgg gccggacgtt
541 cacgcgcgac gaggacctgg ctgttttcct ggcgtcccgc gcgggccgcc tacgcttcca
601 cgggccgggc gcgctgagcg tgggccccga ggactgcgcg gacccgtcgg gctgcgtctg
661 cggcaacgcg gaggcgcagc cgtggatctg cgcggccctg ctccagcccc tgggcggccg
721 ctgtccccag gccgcctgcc actttgccct ccggccccag gggcagtgct gtgacctctg
781 tggagccgtt gtgttgctga cccacggccc cgcatttgac ctggagcggt accgggcgcg
841 gatactggac accttcctgg gtctgcctca gtaccacggg ctgcaggtgg ccgtgtccaa
901 ggtgccacgc tcgtcccggc tccgtgaggc cgatacggag atccaggtgg tgctggtgga
961 gaatgggccc gagacaggcg gagcggggcg gctggcccgg gccctcctgg cggacgtcgc
1021 cgagaacggc gaggccctcg gcgtcctgga ggcgaccatg cgggagtcgg gcgcacacgt
1081 ctggggcagc tccgcggctg ggctggcggg cggcgtggcg gctgccgtgc tgctggcgct
1141 gctggtcctg ctggtggcgc cgccgctgct gcgccgcgcg gggaggctca ggtggaggag
1201 gcacgaggcg gcggccccgg ctggagcgcc cctcggcttc cgcaacccgg tgttcgacgt
1261 gacggcctcc gaggagctgc ccctgccgcg gcggctcagc ctggttccga aggcggccgc
1321 agacagcacc agccacagtt acttcgtcaa ccctctgttc gccggggccg aggccgaggc
1381 ctgagcggcc gcctgaccgt cgaccttggg gctctccacc ccctctggcc ccagtcgaac
1441 tgggggctag ccacctcctc gtccagcccc caaacctccc cttcctttcc ccctcctccg
1501 ggggccaagg acagggtggc cttactcagt aaaggtgttt cctgcacctg ctgtcagcct
1561 ggctatgccg ccaccggccc cgcccatgag gactaggagc ccagccttgc gccgcattcg
1621 cactggggga catgggaggg gtctagctgg ccactgctgg aggcagcgct ggtcgtcacc
1681 tgggcggcca gaggctggga tctgcgaagt tgaacccaga actaggagtg gggcttcccc
1741 cgccttccgg tgaggggagg gtgaggagct ggagggaggg gcgggagaga ggcaaggggt
1801 ggacggagcc aaaggccgtg cctggtgggg cggacggaaa aggggtgggc atccctcctg
1861 gtaccaagct gctgggtgcg aaggcagatc atatgg
//