LOCUS AF328787 6704 bp mRNA linear HUM 06-SEP-2001
DEFINITION Homo sapiens ABC transporter member 7 (ABCA7) mRNA, complete cds.
ACCESSION AF328787
VERSION AF328787.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6704)
AUTHORS Broccardo,C., Osorio,J., Luciani,M.-F., Schriml,L.M., Prades,C.,
Shulenin,S., Arnould,I., Naudin,L., Lafargue,C., Rosier,M.,
Jordan,B., Mattei,M.G., Dean,M., Denefle,P. and Chimini,G.
TITLE Comparative analysis of the promoter structure and genomic
organization of the human and mouse ABCA7 gene encoding a novel
ABCA transporter
JOURNAL Cytogenet. Cell Genet. 92 (3-4), 264-270 (2001)
PUBMED 11435699
REFERENCE 2 (bases 1 to 6704)
AUTHORS Broccardo,C., Osorio,J., Luciani,M.-F., Lynn,S., Prades,C.,
Shulenin,S., Arnould,I., Naudin,L., Lafargue,C., Rosier,M.,
Jordan,B., Mattei,M.G., Dean,M., Denefle,P. and Chimini,G.
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2000) EGC, Aventis-Pharma, 2 Rue Gaston Cremieux,
EVRY, 91 91000, France
FEATURES Location/Qualifiers
source 1..6704
/db_xref="H-InvDB:HIT000077574"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13.3"
gene 1..6704
/gene="ABCA7"
CDS 117..6557
/gene="ABCA7"
/note="ABCA7 protein"
/codon_start=1
/product="ABC transporter member 7"
/protein_id="AAK00959.1"
/translation="MAFWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRH
SHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQLTPGEEPGRLSNFNDSLV
SRLLADARTVLGGASAHRTLAGLGKLIATLRAARSTAQPQPTKQSPLEPPMLDVAELL
TSLLRTESLGLALGQAQEPLHSLLEAAGDLAQELLALRSLVELRALLQRPRGTSGPLE
LLSEALCSVRGPSSTVGPSLNWYEASDLMELVGQEPESALPDSSLSPACSELIGALDS
HPLSRLLWRRLKPLILGKLLFAPDTPFTRKLMAQVNRTFEELTLLRDVREVWEMLGPR
IFTFMNDSSNVAMLQRLLQMQDEGRRQPRPGGRDHMEALRSFLDPGSGGYSWQDAHAD
VGHLVGTLGRVTECLSLDKLEAAPSEAALVSRALQLLAEHRFWAGVVFLGPEDSSDPT
EHPTPDLGPGHVRIKIRMDIDVVTRTNKIRDRFWDPGPAADPLTDLRYVWGGFVYLQD
LVERAAVRVLSGANPRAGLYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTLTV
KAVVREKETRLRDTMRAMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSH
PGVVFLFLAAFAVATVTQSFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLP
AGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADVFSLAQVSGLLLLD
AALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYWCGPRPPKSPAPCPTPLDPKVLVEE
APPGLSPGVSVRSLEKRFPGSPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSG
LFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLKGLSAA
VVGPEQDRLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDP
ASRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLG
SGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPG
ARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKV
VEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSG
PDAVGRVQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPP
FGHYPALRLSPTMYGAQVSFFSEDAPGDPGRARLLEALLQEAGLEEPPVQHSSHRFSA
PEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPPPPQAVTGSGEV
VQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSV
EELWALLSPLPGGALDRVLKNLTAWAHSLDAQDSLKIWFNNKGWHSMVAFVNRASNAI
LRAHLPPGPARHAHSITTLNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPAS
FTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAY
VAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFV
LELFSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDRQFQSPLR
WEVVGKNLLAMVIQGPLFLLFTLLLQHRSQLLPQPRVRSLPLLGEEDEDVARERERVV
QGATQGDVLVLRNLTKVYRGQRMPAVDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTG
DTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFELLTGREHLELLARLRGVPEA
QVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDP
SARRFLWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRF
AAGHTLTLRVPAARSQPAAAFVAAEFPGSELREAHGGRLRFQLPPGGRCALARVFGEL
AVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRV
SQFLDDPSTAETVL"
BASE COUNT 1117 a 2176 c 2152 g 1259 t
ORIGIN
1 gtgggataaa ggaatgaggt tcagaaaggg gcagggagtt gcccgcagcc gcaccgcacg
61 tcttcagccc gaccgttgtc ctgacctctc tgtcccgtcc cctgcccagt ctcaccatgg
121 ccttctggac acagctgatg ctgctgctct ggaagaattt catgtatcgc cggagacagc
181 cggtccagct cctggtcgaa ttgctgtggc ctctcttcct cttcttcatc ctggtggctg
241 ttcgccactc ccacccgccc ctggagcacc atgaatgcca cttcccaaac aagccactgc
301 catcggcggg caccgtgccc tggctccagg gtctcatctg taatgtgaac aacacctgct
361 ttccgcagct gacaccgggc gaggagcccg ggcgcctgag caacttcaac gactccctgg
421 tctcccggct gctagccgat gcccgcactg tgctgggagg ggccagtgcc cacaggacgc
481 tggctggcct agggaagctg atcgccacgc tgagggctgc acgcagcacg gcccagcctc
541 aaccaaccaa gcagtctcca ctggaaccac ccatgctgga tgtcgcggag ctgctgacgt
601 cactgctgcg cacggaatcc ctggggttgg cactgggcca agcccaggag cccttgcaca
661 gcttgttgga ggccgctggg gacctggccc aggagctcct ggcgctgcgc agcctggtgg
721 agcttcgggc actgctgcag agaccccgag ggaccagcgg ccccctggag ttgctgtcag
781 aggccctctg cagtgtcagg ggacctagca gcacagtggg cccctccctc aactggtacg
841 aggctagtga cctgatggag ctggtggggc aggagccaga atccgccctg ccagacagca
901 gcctgagccc cgcctgctcg gagctgattg gagccctgga cagccacccg ctgtcccgcc
961 tgctctggag acgcctgaag cctctgatcc tcgggaagct actctttgca ccagatacac
1021 cttttacccg gaagctcatg gcccaggtga accggacctt cgaggagctc accctgctga
1081 gggatgtccg ggaggtgtgg gagatgctgg gaccccggat cttcaccttc atgaacgaca
1141 gttccaatgt ggccatgctg cagcggctcc tgcagatgca ggatgaagga agaaggcagc
1201 ccagacctgg aggccgggac cacatggagg ccctgcgatc ctttctggac cctgggagcg
1261 gtggctacag ctggcaggac gcacacgctg atgtggggca cctggtgggc acgctgggcc
1321 gagtgacgga gtgcctgtcc ttggacaagc tggaggcggc accctcagag gcagccctgg
1381 tgtcgcgggc cctgcaactg ctcgcggaac atcgattctg ggccggcgtc gtcttcttgg
1441 gacctgagga ctcttcagac cccacagagc acccaacccc agacctgggc cccggccacg
1501 tgcgcatcaa aatccgcatg gacattgacg tggtcacgag gaccaataag atcagggaca
1561 ggttttggga ccctggccca gccgcggacc ccctgaccga cctgcgctac gtgtggggcg
1621 gcttcgtgta cctgcaagac ctggtggagc gtgcagccgt ccgcgtgctc agcggcgcca
1681 acccccgggc cggcctctac ctgcagcaga tgccctatcc gtgctatgtg gacgacgtgt
1741 tcctgcgtgt gctgagccgg tcgctgccgc tcttcctgac gctggcctgg atctactccg
1801 tgacactgac agtgaaggcc gtggtgcggg agaaggagac gcggctgcgg gacaccatgc
1861 gcgccatggg gctcagccgc gcggtgctct ggctaggctg gttcctcagc tgcctcgggc
1921 ccttcctgct cagcgccgca ctgctggttc tggtgctcaa gctgggagac atcctcccct
1981 acagccaccc gggcgtggtc ttcctgttct tggcagcctt cgcggtggcc acggtgaccc
2041 agagcttcct gctcagcgcc ttcttctccc gcgccaacct ggctgcggcc tgcggcggcc
2101 tggcctactt ctccctctac ctgccctacg tgctgtgtgt ggcttggcgg gaccggctgc
2161 ccgcgggtgg ccgcgtggcc gcgagcctgc tgtcgcccgt ggccttcggc ttcggctgcg
2221 agagcctggc tctgctggag gagcagggcg agggcgcgca gtggcacaac gtgggcaccc
2281 ggcctacggc agacgtcttc agcctggccc aggtctctgg ccttctgctg ctggacgcgg
2341 cgctctacgg cctcgccacc tggtacctgg aagctgtgtg cccaggccag tacgggatcc
2401 ctgaaccatg gaattttcct tttcggagga gctactggtg cggacctcgg ccccccaaga
2461 gtccagcccc ttgccccacc ccgctggacc caaaggtgct ggtagaagag gcaccgcccg
2521 gcctgagtcc tggcgtctcc gttcgcagcc tggagaagcg ctttcctgga agcccgcagc
2581 cagccctgcg ggggctcagc ctggacttct accagggcca catcaccgcc ttcctgggcc
2641 acaacggggc cggcaagacc accaccctgt ccatcttgag tggcctcttc ccacccagtg
2701 gtggctctgc cttcatcctg ggccacgacg tccgctccag catggccgcc atccggcccc
2761 acctgggcgt ctgtcctcag tacaacgtgc tgtttgacat gctgaccgtg gacgagcacg
2821 tctggttcta tgggcggctg aagggtctga gtgccgctgt agtgggcccc gagcaggacc
2881 gtctgctgca ggatgtgggg ctggtctcca agcagagtgt gcagactcgc cacctctctg
2941 gtgggatgca acggaagctg tccgtggcca ttgcctttgt gggcggctcc caagttgtta
3001 tcctggacga gcctacggct ggcgtggatc ctgcttcccg ccgcggtatt tgggagctgc
3061 tgctcaaata ccgagaaggt cgcacgctga tcctctccac ccaccacctg gatgaggcag
3121 agctgctggg agaccgtgtg gccgtggtgg caggtggccg cttgtgctgc tgtggctccc
3181 cactcttcct gcgccgtcac ctgggctccg gctactacct gacgctggtg aaggcccgcc
3241 tgcccctgac caccaatgag aaggctgaca ctgacatgga gggcagtgtg gacaccaggc
3301 aggaaaagaa gaatggcagc cagggcagca gagtcggcac tcctcagctg ctggccctgg
3361 tacagcactg ggtgcccggg gcacggctgg tggaggagct gccacacgag ctggtgctgg
3421 tgctgcccta cacgggtgcc catgacggca gcttcgccac actcttccga gagctagaca
3481 cgcggctggc ggagctgagg ctcactggct acgggatctc cgacaccagc ctcgaggaga
3541 tcttcctgaa ggtggtggag gagtgtgctg cggacacaga tatggaggat ggcagctgcg
3601 ggcagcacct atgcacaggc attgctggcc tagacgtaac cctacggctc aagatgccgc
3661 cacaggagac agcgctggag aacggggaac cagctgggtc agccccagag actgaccagg
3721 gctctgggcc agacgccgtg ggccgggtac agggctgggc actgacccgc cagcagctcc
3781 aggccctgct tctcaagcgc tttctgcttg cccgccgcag ccgccgcggc ctgttcgccc
3841 agatcgtgct gcctgccctc tttgtgggcc tggccctcgt gttcagcctc atcgtgcctc
3901 ctttcgggca ctacccggct ctgcggctca gtcccaccat gtacggtgct caggtgtcct
3961 tcttcagtga ggacgcccca ggggaccctg gacgtgcccg gctgctcgag gcgctgctgc
4021 aggaggcagg actggaggag cccccagtgc agcatagctc ccacaggttc tcggcaccag
4081 aagttcctgc tgaagtggcc aaggtcttgg ccagtggcaa ctggacccca gagtctccat
4141 ccccagcctg ccagtgtagc cggcccggtg cccggcgcct gctgcccgac tgcccggctg
4201 cagctggtgg tccccctccg ccccaggcag tgaccggctc tggggaagtg gttcagaacc
4261 tgacaggccg gaacctgtct gacttcctgg tcaagaccta cccgcgcctg gtgcgccagg
4321 gcctgaagac taagaagtgg gtgaatgagg tcagatacgg aggcttctcg ctggggggcc
4381 gagacccagg cctgccctcg ggccaagagt tgggccgctc agtggaggag ttgtgggcgc
4441 tgctgagtcc cctgcctggc ggggccctcg accgtgtcct gaaaaacctc acagcctggg
4501 ctcacagcct ggatgctcag gacagtctca agatctggtt caacaacaaa ggctggcact
4561 ccatggtggc ctttgtcaac cgagccagca acgcaatcct ccgtgctcac ctgcccccag
4621 gcccggcccg ccacgcccac agcatcacca cactcaacca ccccttgaac ctcaccaagg
4681 agcagctgtc tgaggctgca ctgatggcct cctcggtgga cgtcctcgtc tccatctgtg
4741 tggtctttgc catgtccttt gtcccggcca gcttcactct tgtcctcatt gaggagcgag
4801 tcacccgagc caagcacctg cagctcatgg ggggcctgtc ccccaccctc tactggcttg
4861 gcaactttct ctgggacatg tgtaactact tggtgccagc atgcatcgtg gtgctcatct
4921 ttctggcctt ccagcagagg gcatatgtgg cccctgccaa cctgcctgct ctcctgctgt
4981 tgctactact gtatggctgg tcgatcacac cgctcatgta cccagcctcc ttcttcttct
5041 ccgtgcccag cacagcctat gtggtgctca cctgcataaa cctctttatt ggcatcaatg
5101 gaagcatggc cacctttgtg cttgagctct tctctgatca gaagctgcag gaggtgagcc
5161 ggatcttgaa acaggtcttc cttatcttcc cccacttctg cttgggccgg gggctcattg
5221 acatggtgcg gaaccaggcc atggctgatg cctttgagcg cttgggagac aggcagttcc
5281 agtcacccct gcgctgggag gtggtcggca agaacctctt ggccatggtg atacaggggc
5341 ccctcttcct tctcttcaca ctactgctgc agcaccgaag ccaactcctg ccacagccca
5401 gggtgaggtc tctgccactc ctgggagagg aggacgagga tgtagcccgt gaacgggagc
5461 gggtggtcca aggagccacc cagggggatg tgttggtgct gaggaacttg accaaggtat
5521 accgtgggca gaggatgcca gctgttgacc gcttgtgcct ggggattccc cctggtgagt
5581 gttttgggct gctgggtgtg aatggagcag ggaagacgtc cacgtttcgc atggtgacgg
5641 gggacacatt ggccagcagg ggcgaggctg tgctggcagg ccacagcgtg gcccgggaac
5701 ccagtgctgc gcacctcagc atgggatact gccctcaatc cgatgccatc tttgagctgc
5761 tgacgggccg cgagcacctg gagctgcttg cgcgcctgcg cggtgtcccg gaggcccagg
5821 ttgcccagac cgctggctcg ggcctggcgc gtctgggact ctcatggtac gcagaccggc
5881 ctgcaggcac ctacagcgga gggaacaaac gcaagctggc gacggccctg gcgctggttg
5941 gggacccagc cgtggtgttt ctggacgagc cgaccacagg catggacccc agcgcgcggc
6001 gcttcctttg gaacagcctt ttggccgtgg tgcgggaggg ccgttcagtg atgctcacct
6061 cccatagcat ggaggagtgt gaagcgctct gctcgcgcct agccatcatg gtgaatgggc
6121 ggttccgctg cctgggcagc ccgcaacatc tcaagggcag attcgcggcg ggtcacacac
6181 tgaccctgcg ggtgcccgcc gcaaggtccc agccggcagc ggccttcgtg gcggccgagt
6241 tccctgggtc ggagctgcgc gaggcacatg gaggccgcct gcgcttccag ctgccgccgg
6301 gagggcgctg cgccctggcg cgcgtctttg gagagctggc ggtgcacggc gcagagcacg
6361 gcgtggagga cttttccgtg agccagacga tgctggagga ggtattcttg tacttctcca
6421 aggaccaggg gaaggacgag gacaccgaag agcagaagga ggcaggagtg ggagtggacc
6481 ccgcgccagg cctgcagcac cccaaacgcg tcagccagtt cctcgatgac cctagcactg
6541 ccgagactgt gctctgagcc tccctcccct gcggggccgc ggggaggccc tgggaatggc
6601 aagggcaagg tagagtgcct aggagccctg gactcaggct ggcagagggg ctggtgccct
6661 ggagaaaata aagagaaggc tggagagaag ccgtggtggt gaaa
//