LOCUS AF326917 5972 bp mRNA linear HUM 02-DEC-2001
DEFINITION Homo sapiens autism-related protein 1 (AUTS2) mRNA, complete cds.
ACCESSION AF326917
VERSION AF326917.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5972)
AUTHORS Sultana,R., Yu,J., Yu,C.E., Hua,W., Cortes,F., de la Barra,F.,
Haider,S.T., Trask,B.J., Green,E.D., Raskind,W.H., Disteche,C.M.,
Schellenberg,G.D., Storm,D.R. and Villacres,E.C.
TITLE A candidate gene for autism on chromosome 7
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5972)
AUTHORS Sultana,R., Yu,J., Yu,C.E., Hua,W., Cortes,F., de la Barra,F.,
Haider,S.T., Trask,B.J., Green,E.D., Raskind,W.H., Disteche,C.M.,
Schellenberg,G.D., Storm,D.R. and Villacres,E.C.
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2000) Psychiatry & Behavioral Sciences,
University of Washington, 325 9th Ave. Box 359896, Seattle, WA
98104-2499, USA
FEATURES Location/Qualifiers
source 1..5972
/db_xref="H-InvDB:HIT000077507"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q11.2"
gene 1..5972
/gene="AUTS2"
CDS 322..4101
/gene="AUTS2"
/note="autism susceptibility"
/codon_start=1
/product="autism-related protein 1"
/protein_id="AAL37411.1"
/translation="MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTR
ALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEAL
EKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQ
HLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTG
YFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLER
SQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQP
PPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS
AYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQP
PAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSA
DRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDK
YPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTV
PHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGL
KPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAH
LEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHR
TPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPS
PAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEG
HLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYE
NPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTG
IHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRD
PLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERG
GHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQ
NGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR"
BASE COUNT 1466 a 1819 c 1450 g 1237 t
ORIGIN
1 ctgtgtgttc agccattact ttgctcggcg ctgctcccag gcatctccga ccctcggtgc
61 tgtggggagc cccacacttg ggctcctcgc ctctcgccct cgctccccgt ccctcctccc
121 ctctctccgc cccttccccc ttttctttct cctctctttc ttcccctctc tcccttcttt
181 cggccgccgt ctcccccgcg ccctcctcgg ggcggaggga agccgtgaag ggggagggag
241 ggctcggtgt caattttttt ttgtgtggct gcggccgtag cctgtggcgg gcaagcgggg
301 agaccccggc gcagcagaac catggatggc ccgacgcggg gccatggact ccgcaaaaag
361 cggcggtcgc ggtcgcagcg agaccgggag aggcgctccc ggggcgggct gggggccggc
421 gcggccggcg gcggcggggc tggccggacc cgggcgctct cactcgcctc gtcgtcgggc
481 tccgacaagg aagacaatgg gaagcccccg tcctccgccc cgtcccggcc cagacccccg
541 cggaggaagc ggagagagtc cacctcggca gaagaggaca tcattgatgg atttgccatg
601 accagctttg tcacttttga agcgctggag aaagatgtag cacttaagcc tcaggaacgt
661 gtggagaaac gccagacgcc cctgaccaag aagaaacgag aagcacttac caatggcttg
721 tcctttcatt caaagaagag cagactcagc cacccacacc actacagctc agatcgagaa
781 aatgaccgca atctctgcca gcaccttggg aagagaaaga aaatgccgaa ggcactcaga
841 cagctcaagc caggacagaa cagctgcagg gacagtgaca gtgaaagtgc cagtggagaa
901 tccaagggct tccaccggag cagctctcgg gaaaggctca gtgatagttc agctccttcc
961 agcttgggaa caggctactt ctgtgacagt gacagtgacc aggaagagaa ggcatcagat
1021 gccagctctg aaaaactctt caacactgtt attgtaaaca aagatccgga gttaggtgtt
1081 ggcacgctac cagaacatga cagccaggat gcagggccga ttgtccccaa gatatcgggt
1141 ctagagagaa gccaggagaa gagccaggac tgttgcaaag agccaatctt tgagcctgtg
1201 gtgcttaaag acccctgccc tcaggtcgca cagccaatac cccagccgca gacggagccc
1261 caactccgag ctccttctcc ggaccctgac ttggtgcagc gcacagaggc cccacctcaa
1321 cccccacctc tgagtacaca gccaccacag ggccctcctg aggcccagct ccagcctgcc
1381 ccgcagcctc aggtgcagag gccacccagg ccacagtccc ccacccagct gctccatcag
1441 aacctcccac ctgtgcaggc ccacccctct gctcagagcc tctcccagcc attgtcagcc
1501 tacaacagca gtagcttaag cctcaacagt ttaagcagca gcagaagcag cactccagcg
1561 aagactcagc ccgccccacc tcacatctcc caccacccct ctgcctcccc gttccccctc
1621 tccctgccca accacagccc cctgcacagc ttcacaccca ccctccagcc ccccgcacac
1681 tcacatcacc ccaatatgtt tgcccctccc actgctctgc ctcctccacc accactgaca
1741 tcaggaagtc tgcaggtggc cggacacccg gccgggagca cttactcaga gcaagacatc
1801 ttgcgacagg aactgaacac tcgttttttg gcctctcaga gtgctgaccg cggggcttcc
1861 ctgggccctc cgccctacct gcggaccgag ttccatcagc accagcacca gcaccagcac
1921 acccaccagc acacgcacca gcacaccttc acgccgttcc cccacgccat cccacccacc
1981 gccatcatgc cgacgccagc acctcccatg tttgacaaat accctacaaa agttgaccca
2041 ttctaccggc acagtctctt ccattcctat cctcctgcag tgtcgggcat cccccctatg
2101 atcccaccca ctggcccttt tggttcacta caaggagcat ttcagccgaa gacatccaac
2161 cctatcgatg tcgctgctcg gcctgggaca gtcccacaca ctttactcca aaaggacccg
2221 aggttgacag atcctttcag acctatgtta aggaaaccag ggaagtggtg tgctatgcat
2281 gttcacatcg cctggcagat ttaccaccac caacagaaag tcaagaaaca gatgcagtca
2341 gacccacata agctggactt tggactgaaa cctgagttcc tgagccgccc tccaggcccc
2401 agtctttttg gagccatcca ccacccccat gacctggcac ggccttcaac tttgttctct
2461 gccgctggtg ctgcacaccc aactgggacc ccttttgggc cacctcctca tcacagcaac
2521 ttcctcaacc ctgctgccca cctagagcct tttaatcggc cgtctacatt cacaggccta
2581 gcagcagttg gtggcaatgc cttcggggga cttggaaatc cttccgttac acccaactca
2641 atgttcggcc acaaggatgg ccccagtgtg cagaacttta gcaaccctca cgaaccctgg
2701 aaccggctgc accgaacgcc tccgtcgttc ccgacccctc cgccctggct gaagccaggg
2761 gagctggagc gcagcgcgtc cgctgcagct catgacagag atagagatgt agataaacga
2821 gactcatctg ttagtaaaga tgacaaagaa agggaaagcg tcgagaagag acactccagc
2881 cacccttcac cagcacctgt cctcccggtg aatgccctgg gacatacccg cagctccact
2941 gaacagatcc gggctcatct gaacactgag gctcgggaga aggacaaacc caaagagagg
3001 gagagagacc actcggaatc ccgcaaggac ctggccgccg acgagcacaa ggcgaaagag
3061 ggccacctgc ccgagaagga cgggcacggc cacgaggggc gcgccgcggg cgaagaggcc
3121 aagcagctgg cccgggtgcc gtctccctac gtgcggaccc cggtggtgga gagtgccagg
3181 cccaacagca cctcgagccg ggaggccgag ccgcgcaagg gtgagccggc ctacgagaac
3241 cccaagaaga gctccgaggt caaggtgaag gaggagcgga aggaagacca tgacctgcct
3301 ccagaggccc cgcagaccca ccgggcctcg gagccgccgc ctcccaactc ctcgtccagc
3361 gtgcacccgg ggcccctggc ctcgatgccc atgacggtgg gggtgacggg cattcacccc
3421 atgaacagca tcagcagcct ggacaggact cgcatgatga cccccttcat gggcatcagc
3481 cccctcccgg gcggagagcg cttcccgtac ccttctttcc actgggaccc catccgggac
3541 cccttgaggg atccttaccg agaacttgac attcaccgga gagacccgct gggcagggac
3601 ttcctgctaa ggaacgaccc gctccaccgg ctctcgactc cccggctgta cgaagccgac
3661 cgctccttca gggaccggga gcctcacgac tacagccacc accaccacca ccaccaccac
3721 ccgctgtctg tggaccctcg gcgggagcac gagcggggag gccacctgga cgagcgggag
3781 cgcttgcaca tgctcagaga agactacgag cacacgcggc tccactccgt gcaccccgcc
3841 tccctcgacg gacacctccc ccaccccagc ctcatcaccc cgggactccc cagcatgcac
3901 tatccccgca tcagccccac cgcgggcaac cagaacggac tcctcaacaa gacccctccg
3961 acagcagcgc tgagcgcacc tcccccgctc atctccacgc tggggggccg cccggtctct
4021 cccagaagga cgactcctct gtccgcagag ataagggaga ggcccccttc ccacacgctg
4081 aaggatatcg aggcccgata agccgagaac aggagcaaga acgaggaaga agaaacccta
4141 ggcagacacc aggccaggct tgagagacag aactcctgca tggctcacac agactggggg
4201 ggaaagcccc accccttccc cttgtaaaaa atgtatagac tcagtgcaca ttttgaaatg
4261 ttttgtatat tatatgttga gatttttcag atcttttagc ccagtcatat gttctcacgt
4321 ctcctacttt ttgtttctcg tataaaactt tttgatttga accaaaacag tgaagatgac
4381 aacacacacc aattggatga taattgtagc gggggcggtg ggggggagaa gtccacgcca
4441 tccatcatgc aaaattcttt cagatgaggt gggaaggccg tgtacatagt tatgtaaaaa
4501 gagattgctt catgagctaa tggttcatat atgcaaaagg gtaagatgaa agctttactt
4561 tgtacaaatg taaatagata aagtaacata atacattaat acttcttaaa atgtgctatt
4621 tgcaaactta cttaatatca gtgaacacag tcggctaaag ctgtgttccc atatattgtt
4681 atagacagct aaacccttca actatgcaat gaatgttcgg gcttttcaca aaagcccgcc
4741 taactcaaag gagccttttc aaatccattt acagcatact taaggtcata ttttccctga
4801 acaagcgctt acgtgatatg actctgtttt ccttgcttgt tttttttcaa acggagaaac
4861 atcctgtttt gcaaattgga ccccaggctg gaacttagca tctgaagttg ccgcttgtgg
4921 gctctggggg aaagtgtagc cccggagagg taactgagga catgagcaac cagtgccagg
4981 gagggtggga tttgccagat gccaaaatca ggggacgggt ggtggtgtct gtcagacaca
5041 cacaggtcgc cagtgacttc acacacacct catgtgagaa ccatgccttt tttagtgtgt
5101 cctatttcat acctgtacac acttcctcgt tttgtaatga gatttactta cacccaaaca
5161 gatcctgaaa gaaagcttca agttttctca gatgatggat atgttttcac tgtattcaat
5221 aactgacgga tgtaaggtgc acgtttcctg atgtgacgca ctgtattcca gctggtgatc
5281 aagtctggga acagccgtaa caggtcaacc ttgtggagcc atcgcgagtt agagggtgaa
5341 agatggcaga aaaaaaagtc ttgtgtgtga gtgtgttttt tgagtttgca tcaatcttaa
5401 tgtctcttca taatactttt ataatacatt aagcctcttg tctacatatt tggagagaat
5461 atgactttac tagcagagaa atacaatata tcttgtctac tggactgtaa aatatatgta
5521 tgaaataaaa ttagttccat ttggtcttct agtatattaa agtgctatct gacgttgtta
5581 tcctgttttt gcaaaaaaaa aaaaaaaaaa aagttaacta cagaccattg tttctaataa
5641 gcagagagat ctattttagt agtaaactga aggtttagtt gtgagcttca gattttgtga
5701 actccagatg ttgtgcggtg tttttttttt tttttaagac aacaactaaa aaaatgcaag
5761 gaatatgtac actggaactg tagtggtagc tttcagtatt gtaaagagat tgttctatac
5821 ggaccttttt gctgtttatc ctgtatgtaa taaagtcctt tctagatcct atgtgaaaag
5881 aaaagtgaag caactgaatc ttcagcatgt tctcatcggc ggagccttct tgtgtaatgt
5941 aaactgtgcc atgttattaa aaaatgtgaa ct
//