LOCUS AF325549 1791 bp mRNA linear HUM 12-DEC-2001
DEFINITION Homo sapiens skeletal myosin light chain kinase mRNA, complete cds.
ACCESSION AF325549
VERSION AF325549.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1791)
AUTHORS Davis,J.S., Hassanzadeh,S., Winitsky,S., Lin,H., Satorius,C.,
Vemuri,R., Aletras,A.H., Wen,H. and Epstein,N.D.
TITLE The overall pattern of cardiac contraction depends on a spatial
gradient of myosin regulatory light chain phosphorylation
JOURNAL Cell 107 (5), 631-641 (2001)
PUBMED 11733062
REFERENCE 2 (bases 1 to 1791)
AUTHORS Hassanzadeh,S.
TITLE Direct Submission
JOURNAL Submitted (01-DEC-2000) Molecular Physiology, Cardiology, NHLBI,
NIH, Bethesda, MD 20892-1760, USA
FEATURES Location/Qualifiers
source 1..1791
/db_xref="H-InvDB:HIT000077480"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q13.31"
/tissue_type="skeletal muscle"
CDS 1..1791
/codon_start=1
/product="skeletal myosin light chain kinase"
/protein_id="AAK15494.1"
/translation="MATENGAVELGIQNPSTDKAPKGPTGERPLAAGKDPGPPDPKKA
PDPPTLKKDAKAPASEKGDGTLAQPSTSSQGPKGEGDRGGGPAEGSAGPPAALPQQTA
TPETSVKKPKAEQGASGSQDPGKPRVGKKAAEGQAAARRGSPAFLHSPSCPAIISSSE
KLLAKKPPSEASELTFEGVPMTHSPTDPRPAKAEEGKNILAESQKEVGEKTPGQAGQA
KMQGDTSRGIEFQAVPSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRT
GNVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVM
NQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICD
GILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLS
PEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEA
VSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMK
RRWKKNFIAVSAANRFKKISSSGALMALGV"
BASE COUNT 467 a 497 c 526 g 301 t
ORIGIN
1 atggcgacag aaaatggagc agttgagctg ggaattcaga acccatcaac agacaaggca
61 cctaaaggtc ccacaggtga aagacccctg gctgcaggga aagaccctgg ccccccagac
121 ccaaagaaag ctccggatcc acccaccctg aagaaagatg ccaaagcccc tgcctcagag
181 aaaggggatg gtaccctggc ccaaccctca actagcagcc aaggccccaa aggagagggt
241 gacaggggcg gggggcccgc ggagggcagt gctgggcccc cggcagccct gccccagcag
301 actgcgacac ctgagaccag cgtcaagaag cccaaggctg agcagggagc ctcaggcagc
361 caggatcctg gaaagcccag ggtgggcaag aaggcagcag agggccaagc agcagccagg
421 aggggctcac ctgcctttct gcatagcccc agctgtcctg ccatcatctc cagttctgag
481 aagctgctgg ccaagaagcc cccaagcgag gcatcagagc tcacctttga aggggtgccc
541 atgacccaca gccccacgga tcccaggcca gccaaggcag aagaaggaaa gaacatcctg
601 gcagagagcc agaaggaagt gggagagaaa accccaggcc aggctggcca ggctaagatg
661 caaggggaca cctcgagggg gattgagttc caggctgttc cctcagagaa atccgaggtg
721 gggcaggccc tctgtctcac agccagggag gaggactgct tccagatttt ggatgattgc
781 ccgccacctc cggccccctt ccctcaccgc atggtggagc tgaggaccgg gaatgtcagc
841 agtgaattca gtatgaactc caaggaggcg ctcggaggtg gcaagtttgg ggcagtctgt
901 acctgcatgg agaaagccac aggcctcaag ctggcagcca aggtcatcaa gaaacagact
961 cccaaagaca aggaaatggt gttgctggag attgaggtca tgaaccagct gaaccaccgc
1021 aatctgatcc agctgtatgc agccatcgag actccgcatg agatcgtcct gttcatggag
1081 tacatcgagg gcggagagct cttcgagagg attgtggatg aggactacca tctgaccgag
1141 gtggacacca tggtgtttgt caggcagatc tgtgacggga tcctcttcat gcacaagatg
1201 agggttttgc acctggacct caagccagag aacatcctgt gtgtcaacac caccgggcat
1261 ttggtgaaga tcattgactt tggcctggca cggaggtata accccaacga gaagctgaag
1321 gtgaactttg ggaccccaga gttcctgtca cctgaggtgg tgaattatga ccaaatctcc
1381 gataagacag acatgtggag tatgggggtg atcacctaca tgctgctgag cggcctctcc
1441 cccttcctgg gagatgatga cacagagacc ctaaacaacg ttctatctgg caactggtac
1501 tttgatgaag agacctttga ggccgtatca gacgaggcca aagactttgt ctccaacctc
1561 atcgtcaagg accagagggc ccggatgaac gctgcccagt gtctcgccca tccctggctc
1621 aacaacctgg cggagaaagc caaacgctgt aaccgacgcc ttaagtccca gatcttgctt
1681 aagaaatacc tcatgaagag gcgctggaag aaaaacttca ttgctgtcag cgctgccaac
1741 cgcttcaaga agatcagcag ctcgggggca ctgatggctc tgggggtctg a
//