LOCUS AF323540 3004 bp mRNA linear HUM 23-MAY-2001
DEFINITION Homo sapiens apolipoprotein L-I mRNA, splice variant B, complete
cds.
ACCESSION AF323540
VERSION AF323540.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3004)
AUTHORS Duchateau,P.N., Pullinger,C.R., Orellana,R.E., Kunitake,S.T.,
Naya-Vigne,J., O'Connor,P.M., Malloy,M.J. and Kane,J.P.
TITLE Apolipoprotein L, a new human high density lipoprotein
apolipoprotein expressed by the pancreas. Identification, cloning,
characterization, and plasma distribution of apolipoprotein L
JOURNAL J. Biol. Chem. 272 (41), 25576-25582 (1997)
PUBMED 9325276
REFERENCE 2 (bases 1 to 3004)
AUTHORS Duchateau,P.N., Pullinger,C.R., Cho,M.H., Eng,C. and Kane,J.P.
TITLE Apolipoprotein L gene family: tissue-specific expression, splicing,
promoter regions; discovery of a new gene
JOURNAL J. Lipid Res. 42 (4), 620-630 (2001)
PUBMED 11290834
REFERENCE 3 (bases 1 to 3004)
AUTHORS Duchateau,P.N., Pullinger,C.R., Cho,M.H., Eng,C. and Kane,J.P.
TITLE Direct Submission
JOURNAL Submitted (21-NOV-2000) Cardiovascular Research Institute,
University of California, San Francisco, 505 Parnassus Avenue, San
Francisco, CA 94143, USA
FEATURES Location/Qualifiers
source 1..3004
/db_xref="H-InvDB:HIT000077432"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q12.1-q13.1"
CDS 274..1518
/note="apoL-I; high density lipoprotein-associated
protein; splice variant B; minor form"
/codon_start=1
/product="apolipoprotein L-I"
/protein_id="AAG53690.1"
/translation="MRFKSHTVELRRPCSDMEGAALLRVSVLCIWMSALFLGVRVRAE
EAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLL
LLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEF
PRLKSKLEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEG
GSLVLLEPGMELGITAALTGITSSTIDYGKKWWTQAQAHDLVIKSLDKLKEVKEFLGE
NISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQV
ERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQ
ELEEKLNILNNNYKILQADQEL"
BASE COUNT 806 a 684 c 858 g 656 t
ORIGIN
1 gttgtgactt tccctttcga attcctcggt atatcttggg gactggagga cctgtctggt
61 tattatacag acgcataact ggaggtggga tccacacagc tcagaacagc tggatcttgc
121 tcagtctctg ccaggggaag attccttgac ttctggggtg atggagaaga aacaggctgt
181 gctgtgtccc taatgggaaa cgtggctgag acaggggagt gagaagggtg cgttgaagaa
241 tggtgcctgt ggcatgatgc cagctttgca atcatgagat tcaaaagcca cactgtggaa
301 ttgaggaggc cctgcagcga catggaggga gctgctttgc tgagagtctc tgtcctctgc
361 atctggatga gtgcactttt ccttggtgtg agagtgaggg cagaggaagc tggagcgagg
421 gtgcaacaaa acgttccaag tgggacagat actggagatc ctcaaagtaa gcccctcggt
481 gactgggctg ctggcaccat ggacccagag agcagtatct ttattgagga tgccattaag
541 tatttcaagg aaaaagtgag cacacagaat ctgctactcc tgctgactga taatgaggcc
601 tggaacggat tcgtggctgc tgctgaactg cccaggaatg aggcagatga gctccgtaaa
661 gctctggaca accttgcaag acaaatgatc atgaaagaca aaaactggca cgataaaggc
721 cagcagtaca gaaactggtt tctgaaagag tttcctcggt tgaaaagtaa gcttgaggat
781 aacataagaa ggctccgtgc ccttgcagat ggggttcaga aggtccacaa aggcaccacc
841 atcgccaatg tggtgtctgg ctctctcagc atttcctctg gcatcctgac cctcgtcggc
901 atgggtctgg cacccttcac agagggaggc agccttgtac tcttggaacc tgggatggag
961 ttgggaatca cagccgcttt gaccgggatt accagcagta ccatagacta cggaaagaag
1021 tggtggacac aagcccaagc ccacgacctg gtcatcaaaa gccttgacaa attgaaggag
1081 gtgaaggagt ttttgggtga gaacatatcc aactttcttt ccttagctgg caatacttac
1141 caactcacac gaggcattgg gaaggacatc cgtgccctca gacgagccag agccaatctt
1201 cagtcagtac cgcatgcctc agcctcacgc ccccgggtca ctgagccaat ctcagctgaa
1261 agcggtgaac aggtggagag ggttaatgaa cccagcatcc tggaaatgag cagaggagtc
1321 aagctcacgg atgtggcccc tgtaagcttc tttcttgtgc tggatgtagt ctacctcgtg
1381 tacgaatcaa agcacttaca tgagggggca aagtcagaga cagctgagga gctgaagaag
1441 gtggctcagg agctggagga gaagctaaac attctcaaca ataattataa gattctgcag
1501 gcggaccaag aactgtgacc acagggcagg gcagccacca ggagagatat gcctggcagg
1561 ggccaggaca aaatgcaaac tttttttttt ttctgagaca gagtcttgct ctgtcgccaa
1621 gttggagtgc aatggtgcga tctcagctca ctgcaagctc tgcctcccgt gttcaagcga
1681 ttctcctgcc ttggcctccc aagtagctgg gactacaggc gcctaccacc atgcccagct
1741 aatttttgta tttttaatag agatggggtt tcaccatgtt ggccaggatg gtctcgatct
1801 cctgacctct tgatctgccc accttggcct cccaaagtgc tgggattaca ggcgtgagcc
1861 atcgcttttg acccaaatgc aaacatttta ttagggggat aaagagggtg aggtaaagtt
1921 tatggaactg agtgttaggg actttggcat ttccatagct gagcacagca ggggaggggt
1981 taatgcagat ggcagtgcag caaggagaag gcaggaacat tggagcctgc aataagggaa
2041 aaatgggaac tggagagtgt ggggaatggg aagaagcagt ttactttaga ctaaagaata
2101 tattgggggg ccgggtgtag tggctcatgc ctgtaatccg agcactttgg gaggccaagg
2161 cgggcggatc acgaggtcag gagatcaaga ccatcctggc taacacagtg aaaccccgtc
2221 tctactaaaa atacaaaaaa ttagccgggc atggtgcggg cgcctgtagt tccagctaac
2281 tgggcggctg aggcaggaga atggcgtgaa cctgggaggt ggagcttgca gtgagccgag
2341 atatcgccac tgcactccag cctgggtgac agagcgagac tccatctcaa aaaaaaaaaa
2401 aaaaagaata tattgacgga agaatagaga ggaggcttga aggaaccagc aatgagaagg
2461 ccaggaaaag aaagagctga aaatggagaa agcccaagag ttagaacagt tggatacagg
2521 agaagaaaca gcggctccac tacagaccca gccccaggtt caatgtcctc cgaagaatga
2581 agtctttccc tggtgatggt cccctgccct gtctttccag catccactct cccttgtcct
2641 cctgggggca tatctcagtc aggcagcggc ttcctgatga tggtcgttgg ggtggttgtc
2701 atgtgatggg tccctccagg ttactaaagg gtgcatgtcc cctgcttgaa cactgaaggg
2761 caggtggtgg gccatggcca tggtccccag ctgaggagca ggtgtccctg agaacccaaa
2821 cttcccagag agtatgtgag aaccaaccaa tgaaaacagt cccatcgctc ttacccggta
2881 agtaaacagt cagaaaatta gcatgaaagc agtttagcat tgggaggaag ctcagatctc
2941 tagagctgtc ttgtcgccgc ccaggattga cctgtgtgta agtcccaata aactcaccta
3001 ctca
//