LOCUS AF322916 4428 bp mRNA linear HUM 15-FEB-2001
DEFINITION Homo sapiens uveal autoantigen mRNA, complete cds.
ACCESSION AF322916
VERSION AF322916.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4428)
AUTHORS Yamada,K., Senju,S., Nakatsura,T., Murata,Y., Ishihara,M.,
Nakamura,S., Ohno,S., Negi,A. and Nishimura,Y.
TITLE Identification of a novel autoantigen UACA in patients with
panuveitis
JOURNAL Biochem. Biophys. Res. Commun. 280 (4), 1169-1176 (2001)
PUBMED 11162650
REFERENCE 2 (bases 1 to 4428)
AUTHORS Yamada,K., Senju,S. and Nishimura,Y.
TITLE Direct Submission
JOURNAL Submitted (20-NOV-2000) Kumamoto University Graduate School of
Medical Sciences, Division of Immunogenetics, Department of
Neuroscience and Immunology, 2-2-1 Honjo, Kumamoto 860-0811, Japan
FEATURES Location/Qualifiers
source 1..4428
/db_xref="H-InvDB:HIT000077426"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 50..4300
/note="contains ankyrin repeats and coiled-coil domains"
/codon_start=1
/product="uveal autoantigen"
/protein_id="AAG49577.1"
/translation="MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAER
GDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGR
NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALQKKAMADCPSSIQLLCDHGASV
NAKDVKGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV
LIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRN
LTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEE
VMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKE
DMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMR
TFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYE
SEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQ
IKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLA
LSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHV
KPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEM
KNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSR
LETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMS
NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENT
QNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKK
ELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQEN
DKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEK
LVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQ
QTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKL
QSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVL
HAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNK
ITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQ
EVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC"
BASE COUNT 1707 a 727 c 1026 g 968 t
ORIGIN
1 gcactccgca gcctttaagg ttcgcgcggg ggccaggcaa gagttagcca tgaagagcct
61 caagtcccgc ctgaggaggc aggacgtgcc cggccccgcg tcgtctggcg ccgccgccgc
121 cagcgcgcat gcagcagatt ggaataaata tgatgaccga ttgatgaaag cagcagaaag
181 gggggatgta gaaaaagtga cctcaatcct tgctaaaaag ggggtcaatc caggcaaact
241 agatgtggaa ggcagatctg tcttccatgt tgtgacctca aaggggaatc ttgagtgttt
301 gaatgccatc cttatacatg gagttgatat tacaaccagt gacactgcag ggagaaatgc
361 tcttcacctg gctgctaagt atggacatgc attgtgccta caaaaacttc tacagtacaa
421 ttgtcccact gagcatgcag acctgcaggg aagaactgca cttcaaaaaa aagcaatggc
481 agattgtcct tctagcatac agctgctttg tgaccatggg gcctctgtga atgccaaaga
541 tgtaaaaggg cggacaccac ttgttctggc tactcagatg agtaggccaa caatatgtca
601 actgctgata gatagaggag cggatgttaa ttccagagac aaacaaaaca gaactgccct
661 catgctaggt tgcgaatatg gttgcagaga tgcagtagaa gtcttaatta aaaatggtgc
721 tgatataagc ttgctggatg cgcttggcca tgatagttct tactatgcaa gaattggtga
781 caatctggac attctaacct tgttgaagac tgcatcggaa aataccaaca aagggagaga
841 actttggaag aaaggaccat ctttgcaaca gcgaaatttg acacacatgc aagatgaagt
901 aaatgtgaag tcacatcaga gggagcatca aaatattcag gatttggaga ttgaaaatga
961 agatttgaaa gagaggttga gaaaaattca gcaagaacaa agaatacttt tggataaagt
1021 caatggttta cagttacagc tgaatgagga agttatggtt gctgatgatc tggaaagcga
1081 gagagaaaag ctgaagtccc ttttggcagc taaagaaaag caacatgaag aaagcttaag
1141 gactattgag gctctgaaaa atagatttaa atattttgag agtgatcatt taggatcagg
1201 aagtcatttc agtaaccgaa aagaagatat gcttcttaaa caaggtcaga tgtatatggc
1261 agactcacag tgtacttccc caggtatacc agcccatatg caaagcagat ctatgttaag
1321 acctctggaa ctatctttac ccagtcaaac gtcatactct gaaaatgaaa ttttaaagaa
1381 agagttagaa gcaatgcgaa ctttctgtga gtcagcaaaa caagaccgac tgaagctcca
1441 aaatgaactg gcacacaaag tggcagaatg caaagcttta gcattagaat gtgaaagggt
1501 caaggaggat tcagatgaac agataaagca attagaagat gcattaaaag atgtgcagaa
1561 gaggatgtat gagtcagaag gtaaagttaa acaaatgcag acccattttc ttgcccttaa
1621 agaacactta acaagtgaag cagcctcagg gaatcacaga ctaaccgagg aactgaagga
1681 tcagttgaaa gacttgaaag taaaatatga aggtgcttca gcagaagtgg ggaaattaag
1741 aaaccaaatc aaacaaaatg agatgatagt agaagagttt aagagggatg aaggcaagct
1801 gatagaagaa aataagcgat tacagaagga acttagtatg tgtgaaatgg agcgagagaa
1861 gaaaggaaga aaggtcacag agatggaagg ccaggcaaaa gaattgtcag cgaagttggc
1921 cctttccatt ccagctgaaa aatttgaaaa catgaagagc tcattatcaa atgaagtgaa
1981 tgagaaagca aaaaaattag tagaaatgga aagagaacat gaaaaatcac ttagtgaaat
2041 tagacagtta aagagagaac ttgagaatgt taaggccaag cttgctcagc acgtcaaacc
2101 agaggaacat gaacaggtta agagcagatt agaacagaaa tcaggagaac ttgggaagaa
2161 gatcactgag ttaacattga aaaatcagac actacaaaag gaaattgaaa aagtttattt
2221 ggataataag ctcctcaagg agcaagcaca taacttaaca attgaaatga aaaatcatta
2281 tgttccttta aaagtaagtg aagacatgaa aaagtcacat gatgcaatta ttgatgatct
2341 taatagaaag cttttagatg taacacaaaa atatacagaa aagaagttgg aaatggagaa
2401 attgctactg gaaaatgaca gcttaagtaa ggatgtaagc cgcctagaaa ctgtgtttgt
2461 acctcctgag aaacatgaaa aagagataat agctctgaaa tccaatattg ttgaacttaa
2521 gaaacagctg tctgaactta agaaaaaatg tggtgaagac caggagaaaa tacacgctct
2581 cacatctgaa aacactaact tgaagaagat gatgagtaat cagtatgtgc cagttaaaac
2641 ccatgaagag gttaaaatga cactgaatga cacgttagcc aaaactaaca gagaattatt
2701 agatgtgaag aaaaaatttg aagatataaa tcaggaattt gtaaaaataa aagataagaa
2761 tgaaatatta aaaagaaacc tggaaaacac tcagaaccaa ataaaagctg agtacatcag
2821 cctggcagag cacgaggcaa agatgagctc gctaagtcag agcatgagaa aggtgcagga
2881 tagtaatgct gaaatcttgg ccaactacag aaaaggccaa gaagagattg tgacactgca
2941 tgccgaaatt aaagcccaga agaaggagct cgacacaata caagaatgca ttaaggtaaa
3001 atatgcccca attgtcagct ttgaggagtg cgagagaaaa tttaaagcaa cagagaaaga
3061 actaaaagac cagttatcag agcagacaca aaagtatagt gtcagtgaag aagaagtcaa
3121 gaaaaacaag caagagaatg acaagttaaa gaaggagatt tttacccttc agaaagattt
3181 gagagataag acagttctca ttgagaagtc tcatgaaatg gaaagagcat taagcagaaa
3241 aacagacgag ctaaacaaac agttaaaaga cttgtcacag aaatacacgg aagtaaagaa
3301 tgtgaaagag aagctagtag aagaaaatgc caaacagact tctgagatac ttgcagtgca
3361 aaatcttttg caaaaacaac atgttccatt ggaacaggtt gaggctctga aaaaatctct
3421 taatggcaca attgaaaatc taaaggaaga actgaagagt atgcaaaggt gttacgagaa
3481 agagcagcag acagtgacca aactgcatca attgttggag aatcaaaaga actcttctgt
3541 acccctggca gagcatttgc agattaaaga agcatttgag aaagaagttg gaatcataaa
3601 agccagcttg agagaaaagg aagaagaaag ccaaaacaaa atggaagaag tctccaaact
3661 tcagtcggag gttcagaata ctaaacaagc attaaaaaaa ttagagacta gagaggtagt
3721 tgacttgtct aaatataaag caacaaaaag tgatttggag acacagattt ctagcttaaa
3781 tgaaaaattg gccaatctga atagaaagta tgaggaagta tgtgaggaag ttttgcatgc
3841 caaaaagaag gaaatatctg caaaagatga gaaggaatta ctgcatttca gcattgagca
3901 agaaattaag gatcagaagg aacgatgtga taagtcctta acaacaatca cagagttaca
3961 aagaagaata caagaatctg ctaaacaaat agaagcaaaa gataataaga taactgaact
4021 gcttaatgat gtggaaagat taaaacaggc actcaatggc ctttcccaac tcacctacac
4081 aagtgggaac cccaccaaga ggcagagcca gctgattgac actctgcagc accaagtgaa
4141 atctctggag caacagctgg ccgatgctga cagacagcac caagaagtaa ttgcaattta
4201 tcggacacac cttcttagtg ctgcacaggg tcacatggat gaagatgttc aggaggctct
4261 gctccagatc atacaaatgc ggcaggggct tgtgtgctag ccgttagcac tgactgccag
4321 tatctgtttt atcttgctgg tgctgaacat tctttgtgca actccatggt ctttctgggc
4381 cttactgtgc tggtataatt aaaataaaat atattttgtt ctgggtgt
//