LOCUS AF319995 3340 bp mRNA linear HUM 21-OCT-2002
DEFINITION Homo sapiens helicase B mRNA, complete cds.
ACCESSION AF319995
VERSION AF319995.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3340)
AUTHORS Taneja,P., Gu,J., Peng,R., Carrick,R., Uchiumi,F., Ott,R.D.,
Gustafson,E., Podust,V.N. and Fanning,E.
TITLE A dominant-negative mutant of human DNA helicase B blocks the onset
of chromosomal DNA replication
JOURNAL J. Biol. Chem. 277 (43), 40853-40861 (2002)
PUBMED 12181327
REFERENCE 2 (bases 1 to 3340)
AUTHORS Taneja,P. and Fanning,E.
TITLE Direct Submission
JOURNAL Submitted (07-NOV-2000) Molecular Biology, Vanderbilt University,
1161 21st Avenue South, Nashville, TN 37215, USA
FEATURES Location/Qualifiers
source 1..3340
/db_xref="H-InvDB:HIT000077343"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..3264
/codon_start=1
/product="helicase B"
/protein_id="AAM73554.1"
/translation="MARSSPYLRQLQGPLLPPRDLVEEDDDYLNDDVEEDEESVFIDA
EELCSGGVKAGSLPGCLRVSICDENTQETCKVFGRFPITGAWWRVKVQVKPVVGSRSY
QYQVQGFPSYFLQSDMSPPNQKHICALFLKECEVSSDDVNKFLTWVKEVSNYKNLNFE
NLRETLRTFHKETGRKDQKQPTQNGQEELFPDNEMSLPLENTIPFRNVMTALQFPKIM
EFLPVLLPRHFKWIIGSGSKEMLKEIEEILGTHPWKLGFSKITYREWKLLRCEASWIA
FCQCESLLQLMTDLEKNALIMYSRLKQICREDGHTYVEVNDLTLTLSNHMSFHAASES
LKFLKDIGVVTYEKSCVFPYDLYHAERAIAFSICDLMKKPPWHLCVDVEKVLASIHTT
KPENSSDDALNESKPDEVRLENPVDVVDTQDNGDHIWTNGENEINAEISEVQLDQDQV
EVPLDRDQVAALEMICSNPVTVISGKGGCGKTTIVSRLFKHIEQLEEREVKKACEDFE
QDQNASEEWITFTEQSQLEADKAIEVLLTAPTGKAAGLLRQKTGLHAYTLCQVNYSFY
SWTQTMMTTNKPWKFSSVRVLVVDEGSLVSVGIFKSVLNLLCEHSKLSKLIILGDIRQ
LPSIEPGNLLKDLFETLKSRNCAIELKTNHRAESQLIVDNATRISRRQFPKFDAELNI
SDNPTLPISIQDKTFIFVRLPEEDASSQSSKTNHHSCLYSAVKTLLQENNLQNAKTSQ
FIAFRRQDCDLINDCCCKHYTGHLTKDHQSRLVFGIGDKICCTRNAYLSDLLPENISG
SQQNNDLDASSEDFSGTLPDFAKNKRDFESNVRLCNGEIFFITNDVTDVTFGKRRSLT
INNMAGLEVTVDFKKLMKYCRIKHAWARTIHTFQGSEEQTVVYVVGKAGRQHWQHVYT
AVTRGRCRVYVIAEESQLRNAIMKNSFPRKTRLKHFLQSKLSSSGAPPADFPSPRKSS
GDSGGPSTPSASPLPVVTDHAMTNDVTWSEASSPDERTLTFAERWQLSSPDGVDTDDD
LPKSRASKRTCGVNDDESPSKIFMVGESPQVSSRLQNLRLNNLIPRQLFKPTDNQET"
BASE COUNT 1045 a 645 c 748 g 902 t
ORIGIN
1 atggccaggt cgagtccgta cctgcgtcaa cttcagggac ctctgctccc acccagggat
61 ctggtggagg aggacgacga ctacctaaac gacgacgtgg aggaggatga agagtccgtg
121 ttcatcgacg ccgaggagct ctgcagtggg ggcgtaaagg ctggcagcct ccccgggtgc
181 ctccgcgttt ctatttgtga tgaaaacaca caagagacat gtaaagtgtt tggacgtttt
241 ccgataacag gtgcttggtg gagagtgaag gtacaagtaa agcctgtggt gggatcaagg
301 agctatcaat atcaagttca aggatttccg tcttactttt tgcagtctga tatgtcacca
361 ccaaatcaaa aacatatctg tgctctcttt cttaaagagt gtgaggtctc cagtgatgat
421 gttaataaat ttttaacatg ggtaaaggag gtatcaaact acaaaaacct aaactttgaa
481 aatcttaggg aaacactaag aactttccac aaggaaactg gaaggaaaga tcaaaagcag
541 cctacacaga atggtcagga agagttgttc ccagacaatg agatgagtct tcctctggaa
601 aacacaattc catttagaaa tgtaatgaca gctttgcagt ttccgaagat aatggaattc
661 cttccagttc ttctgcctcg acactttaaa tggatcatag ggtcaggttc taaagagatg
721 ttgaaagaga tagaagagat tttaggtaca catccgtgga aacttggatt tagtaaaata
781 acctacagag agtggaaact cctgcgatgt gaggcaagtt ggatagcatt ttgtcagtgt
841 gagtctcttc tccagctgat gactgatttg gagaagaatg cattaataat gtattccaga
901 ctgaagcaga tatgtagaga agatgggcac acatatgttg aagtgaatga cttaactttg
961 acattgtcaa atcatatgtc atttcatgct gcttcagagt ctctgaagtt tttgaaggat
1021 attggtgtgg tgacatatga gaagtcctgt gtcttccctt atgaccttta ccatgctgaa
1081 agagccatcg ccttttcaat ttgtgacctg atgaagaaac ctccttggca tttatgtgtc
1141 gatgtcgaaa aggtgcttgc ctctattcac accacaaaac ctgagaattc aagcgatgat
1201 gcattgaatg agagcaaacc tgatgaagta agattagaaa atcctgtgga tgttgtggac
1261 acacaggaca atggtgacca tatttggact aatggtgaaa atgaaattaa tgcagaaata
1321 agtgaagttc agctggatca ggatcaggtt gaagttccac tggatcggga tcaggtggct
1381 gctttggaaa tgatttgctc caatcctgtg acagtcataa gtgggaaagg tggatgtggg
1441 aagaccacaa tcgttagccg tctttttaag catatagagc agttggaaga aagagaagta
1501 aaaaaagcct gtgaagattt tgaacaagac cagaatgctt cagaagaatg gattaccttt
1561 actgagcaaa gtcaactaga ggcggacaag gctatagaag ttttgctcac agcacctaca
1621 gggaaagcag ctggcttact aagacagaaa actggtcttc atgcctacac actgtgtcag
1681 gtcaattata gcttctattc atggactcaa acaatgatga ccacaaacaa accatggaaa
1741 ttttcttcgg ttagagttct ggttgtggat gaagggagtt tggtatctgt agggatcttc
1801 aaatcggtct taaatttatt gtgtgagcac tccaaacttt ctaagcttat tatccttggt
1861 gacattagac agttacccag tattgaacct ggtaacttgc tgaaagatct ttttgagact
1921 cttaagtcaa gaaattgtgc tattgagcta aagacaaacc atagagcaga atctcagctc
1981 attgtggaca atgctacaag aatctcaaga cgccaatttc caaaatttga tgcagaacta
2041 aatatctctg ataatccaac attacccatc tcaattcaag ataagacatt tatttttgtc
2101 aggctcccag aagaggatgc cagttctcag tcatctaaaa ctaatcatca ctcttgttta
2161 tattctgcag ttaaaacttt actacaagaa aataacttac aaaatgcaaa aacatcacaa
2221 tttattgcat ttagaaggca agactgtgat ctaattaatg actgctgctg caaacactac
2281 acaggccacc tcaccaaaga ccatcagagt agacttgttt ttggaattgg tgataaaatt
2341 tgttgtacca ggaatgcata cctctcagac ttactacctg aaaatatctc tggaagtcag
2401 caaaataatg atctagatgc cagtagtgaa gacttttctg gtacgcttcc tgattttgct
2461 aaaaataagc gtgactttga aagtaacgtt cgactgtgca atggagagat atttttcata
2521 acaaatgatg taactgatgt aacttttgga aagagaagat ctttgaccat taataatatg
2581 gctggcctgg aagtaactgt ggattttaag aaactaatga aatattgtcg cataaaacat
2641 gcatgggcaa gaactattca cacttttcag gggtccgagg agcaaacagt tgtctatgtg
2701 gtggggaagg cgggccgcca gcactggcag catgtctaca ccgccgtgac caggggccgc
2761 tgccgagtgt atgtgattgc agaggagtct cagctccgga atgccattat gaaaaacagt
2821 tttcctagaa aaactcgttt gaaacatttc ttgcaaagta agctctcctc tagcggcgca
2881 cctccagcag attttccgtc cccacggaag agctctggag acagtggagg acccagcaca
2941 ccgtcagcat ctccactccc tgtagtcaca gaccacgcca tgacaaatga tgtcacctgg
3001 agcgaggcct cttcgcctga tgagaggaca ctcacctttg ctgaaagatg gcaattatct
3061 tcacctgatg gagtagatac agatgatgat ttaccaaaat cgcgagcatc caaaagaacc
3121 tgtggtgtga atgatgatga aagtccaagc aaaattttta tggtgggaga atctccacaa
3181 gtgtcttcca gacttcagaa tttgagactg aataatttaa ttcccaggca acttttcaag
3241 cccaccgata atcaagaaac ttagttttat ttcaaattgt tccgagtaac tatgtttttc
3301 tattggagac aaaatgaaca tcgtaacgtc aaagtaccaa
//