LOCUS AF314090 1938 bp mRNA linear HUM 30-JAN-2001
DEFINITION Homo sapiens claudin 14 (CLDN14) mRNA, complete cds.
ACCESSION AF314090
VERSION AF314090.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1938)
AUTHORS Wilcox,E.R., Burton,Q.L., Naz,S., Riazuddin,S., Smith,T.N.,
Ploplis,B., Belyantseva,I., Ben-Yosef,T., Liburd,N.A., Morell,R.J.,
Kachar,B., Wu,D.K., Griffith,A.J., Riazuddin,S. and Friedman,T.B.
TITLE Mutations in the gene encoding tight junction claudin-14 cause
autosomal recessive deafness DFNB29
JOURNAL Cell 104 (1), 165-172 (2001)
PUBMED 11163249
REFERENCE 2 (bases 1 to 1938)
AUTHORS Wilcox,E.R., Burton,Q.L., Naz,S., Riazuddin,S., Smith,T.N.,
Ploplis,B., Belyantseva,I., Ben-Yosef,T., Liburd,N.A., Morell,R.J.,
Kachar,B., Wu,D.K., Griffith,A.J., Riazuddin,S. and Friedman,T.B.
TITLE Direct Submission
JOURNAL Submitted (16-OCT-2000) Laboratory of Molecular Genetics (LMG),
National Institute on Deafness and Other Communication Disorders
(NIDCD, NIH), 5 Lopa Court, 2A-19, Rockville, MD 20850, USA
FEATURES Location/Qualifiers
source 1..1938
/db_xref="H-InvDB:HIT000077093"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.1"
/tissue_type="liver"
gene 1..1938
/gene="CLDN14"
CDS 868..1587
/gene="CLDN14"
/codon_start=1
/product="claudin 14"
/protein_id="AAG60052.1"
/translation="MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAV
SYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGM
KCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEI
GQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYK
DNRAPSVTSATHSGYRLNDYV"
BASE COUNT 421 a 540 c 566 g 411 t
ORIGIN
1 cgccaggtgg tggctcagag gaggacacag tcgctgtggg caggtggtca gggcgcagga
61 gggaatgagc tgtggatttt tagtaatcta caacaatcag gcagttccag gacacaggga
121 agtgagtgtg aacagccaat ggacccggag ccgagagcct gggcaggcgt aggctggact
181 atggacgccc tgcaaccctg ccaggctggg aaggggaggc ttgatcctga gcgcgtgtta
241 ggaaggagat gcccaggttc aggtgtatcg tgcatttttt ttccacagtg cagaaatgac
301 atttctggtt ggtcttgaat gtctgctctg gccaagccac ctcctctcat gctagctaac
361 caagtggcac gtgtgcccac gcaggccgtt ctaaggaaca ctgtaattgt ctacacaatt
421 ttctctcaaa tactccgtcc tggaagcgtc tggttggcag aagagggaag gcaggagggt
481 ggcagcgtcc cggctgagtc ctcttgcaca tgggagctgg agtccagcca ggctccagag
541 cggctccggc tggcaaggga cctgaacagg aagatgagac tcgaggtttt ctgcatgcct
601 ggaagtgcac atgctcatct acagctttct tggaagaaga aagaaacaaa aactgagatt
661 tagaacacca ggtctgtttc cactggcggc cactcttggg cactggagac cagcaagagc
721 tttgttttta aaaggctctt ccatggcaga tattcgcaga ggcatcaggg ctacacttaa
781 atgaagggct ccggctggca cctgaggagc ggcgtgaccc cgagggccca gggagctgcc
841 cggctggcct aggcaggcag ccgcaccatg gccagcacgg ccgtgcagct tctgggcttc
901 ctgctcagct tcctgggcat ggtgggcacg ttgatcacca ccatcctgcc gcactggcgg
961 aggacagcgc acgtgggcac caacatcctc acggccgtgt cctacctgaa agggctctgg
1021 atggagtgtg tgtggcacag cacaggcatc taccagtgcc agatctaccg atccctgctg
1081 gcgctgcccc aagacctcca ggctgcccgc gccctcatgg tcatctcctg cctgctctcg
1141 ggcatagcct gcgcctgcgc cgtcatcggg atgaagtgca cgcgctgcgc caagggcaca
1201 cccgccaaga ccacctttgc catcctcggc ggcaccctct tcatcctggc cggcctcctg
1261 tgcatggtgg ccgtctcctg gaccaccaac gacgtggtgc agaacttcta caacccgctg
1321 ctgcccagcg gcatgaagtt tgagattggc caggccctgt acctgggctt catctcctcg
1381 tccctctcgc tcattggtgg caccctgctt tgcctgtcct gccaggacga ggcaccctac
1441 aggccctacc aggccccgcc cagggccacc acgaccactg caaacaccgc acctgcctac
1501 cagccaccag ctgcctacaa agacaatcgg gccccctcag tgacctcggc cacgcacagc
1561 gggtacaggc tgaacgacta cgtgtgagtc cccacagcct gcttctcccc tgggctgctg
1621 tgggctgggt ccccggcggg actgtcaatg gaggcagggg ttccagcaca aagtttactt
1681 ctgggcaatt tttgtatcca aggaaataat gtgaatgcga ggaaatgtct ttagagcaca
1741 gggacagagg gggaaataag aggaggagaa agctctctat accaaagact gaaaaaaaaa
1801 atcctgtctg tttttgtatt tattatatat atttatgtgg gtgatttgat aacaagttta
1861 atataaagtg acttgggagt ttggtcagtg gggttggttt gtgatccagg aataaacctt
1921 gcggatgtgg ctgtttat
//