LOCUS AF312230 3689 bp mRNA linear HUM 22-FEB-2001
DEFINITION Homo sapiens histamine receptor H4 subtype mRNA, complete cds.
ACCESSION AF312230
VERSION AF312230.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3689)
AUTHORS Liu,C., Ma,X.-J., Jiang,X., Wilson,S.J., Hofstra,C.L., Blevitt,J.,
Pyati,J., Li,X., Chai,W., Carruthers,N. and Lovenberg,T.W.
TITLE Cloning and pharmacological characterization of a fourth histamine
receptor (H(4)) expressed in bone marrow
JOURNAL Mol. Pharmacol. 59 (3), 420-426 (2001)
PUBMED 11179434
REFERENCE 2 (bases 1 to 3689)
AUTHORS Liu,C., Ma,X.-J., Jiang,X., Wilson,S.J., Hofstra,C.L., Blevitt,J.,
Pyati,J., Li,X., Chai,W., Carruthers,N. and Lovenberg,T.W.
TITLE Direct Submission
JOURNAL Submitted (10-OCT-2000) Molecular Pharmacology, R.W. Johnson
Pharmaceutical Research Institute, 3210 Merryfield Row, San Diego,
CA 92121, USA
FEATURES Location/Qualifiers
source 1..3689
/db_xref="H-InvDB:HIT000077033"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
CDS 101..1273
/note="G-protein coupled receptor"
/codon_start=1
/product="histamine receptor H4 subtype"
/protein_id="AAK12081.1"
/translation="MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDK
NLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASV
YNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDE
GSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTA
VSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKM
GSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATG
PKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS"
BASE COUNT 975 a 739 c 746 g 1229 t
ORIGIN
1 ggaagactac acattttagg tatgtgatta gaaaacatac ttgtcagaat tgtctggctg
61 gattaatttg ctaatttgac cttcttcatc atttgatgtg atgccagata ctaatagcac
121 aatcaattta tcactaagca ctcgtgttac tttagcattt tttatgtcct tagtagcttt
181 tgctataatg ctaggaaatg ctttggtcat tttagctttt gtggtggaca aaaaccttag
241 acatcgaagt agttattttt ttcttaactt ggccatctct gacttctttg tgggtgtgat
301 ctccattcct ttgtacatcc ctcacacgct gttcgaatgg gattttggaa aggaaatctg
361 tgtattttgg ctcactactg actatctgtt atgtacagca tctgtatata acattgtcct
421 catcagctat gatcgatacc tgtcagtctc aaatgctgtg tcttatagaa ctcaacatac
481 tggggtcttg aagattgtta ctctgatggt ggccgtttgg gtgctggcct tcttagtgaa
541 tgggccaatg attctagttt cagagtcttg gaaggatgaa ggtagtgaat gtgaacctgg
601 atttttttcg gaatggtaca tccttgccat cacatcattc ttggaattcg tgatcccagt
661 catcttagtc gcttatttca acatgaatat ttattggagc ctgtggaagc gtgatcatct
721 cagtaggtgc caaagccatc ctggactgac tgctgtctct tccaacatct gtggacactc
781 attcagaggt agactatctt caaggagatc tctttctgca tcgacagaag ttcctgcatc
841 ctttcattca gagagacaga ggagaaagag tagtctcatg ttttcctcaa gaaccaagat
901 gaatagcaat acaattgctt ccaaaatggg ttccttctcc caatcagatt ctgtagctct
961 tcaccaaagg gaacatgttg aactgcttag agccaggaga ttagccaagt cactggccat
1021 tctcttaggg gtttttgctg tttgctgggc tccatattct ctgttcacaa ttgtcctttc
1081 attttattcc tcagcaacag gtcctaaatc agtttggtat agaattgcat tttggcttca
1141 gtggttcaat tcctttgtca atcctctttt gtatccattg tgtcacaagc gctttcaaaa
1201 ggctttcttg aaaatatttt gtataaaaaa gcaacctcta ccatcacaac acagtcggtc
1261 agtatcttct taaagacaat tttctcacct ctgtaaattt tagtctcaat ctcacctaaa
1321 tgaatcaggt ctgcccttta tcttgccctt ttcattctac caacagatct gcactttgaa
1381 gtcaatggta aattactcca gtgaataata gcagtataat atgacttgat aatatttttg
1441 taaacttgta gtcataatag tactatattc ttcttagtcc tcacctcttc cttgtctttt
1501 agatcttaat ttcatgctga ttacaaaaat ccagttttgt tttctttcta tgttccatgc
1561 ataatacagt cttaagtgaa tttctctttt ttaattttat cgtaatagaa acttatccag
1621 tttgaaaatc attccctaaa gcatgcaata ggaaaaagaa cctcctggct gggactgccc
1681 aactctgttc tgatcagtgg gtgggtgagg tagggtttga gttggcaaga gcagggaacg
1741 ggcatgtgcc caggtgagct cctgtgtgtg tccagatttt atattcctaa tcccagtaag
1801 gaagaaagcg tagtgtggga gaggagagag ctgatgactg cagttctcaa aggtcctcag
1861 tgaagttatt ttggaggccc tggtggtcac aggatcagaa ggcaagggat aggcagtggt
1921 caccaatggt tgaaagtatg gcttgtccca tttcttcctg ttctcttttt ctagcttcca
1981 catcagcttc cttttttgag aacatataga agaagaaggc taagagatgg tgaagagact
2041 gcatgattaa actagataga cctggtatac agtcactgaa ctagtagatg tcaataatta
2101 ttatttttaa aaatttttat ttgttggccg ggcatggtgg ctcacgcctg aaatcccagc
2161 actttgggag gccaaggtgg gcggatcatg aggtcaggag atcgagacca tcctggccaa
2221 catggtgaaa ccccatctgt actaaaatac aaacaagtag ctggttgtgg cgccgcatgc
2281 ctgtagtccc agctactcgg gaggctgagg caggggaatt gcttgaaccc gggaggcgga
2341 gttttgccag cctggcaaca gagcaagact ctgtctaaaa agaaaaaaaa atttttttgt
2401 ttgagacagc atcttgctct gtctcccagg ctggagcgta gtaatgcaat catagctcac
2461 tgcagcctgg aactccttgg ctcaagcaat cctgctgcct tggcctccca agtatgtggg
2521 actacaggta ctcgccacca cacctggata attaaaaaat tatttctgta gagatgaagt
2581 ctcactgtgt tgcccagcct gggtgtcaat aattattttt taaaaaaaat ttttaaaaag
2641 gttttttgag acagattctt gctctgtcac ccaggctgga gtgcagtagc atgatcaggg
2701 atcactgcaa cctctgcctc ctgggttcaa gcgattcttg tgcctaagcc acctgagcag
2761 ctgggattgc aggtgcatgc caccatgcct ggctaatttt ggtattttta gtagagatga
2821 ggttttgcca ttttggtcag gctggaattt tttttttttt taattttgat aagacagggt
2881 attgccgtgt tggccagact ggtctcaaac tcctgggctg aaacaatcct cccgccttgg
2941 cctcccaaag tgctgggatt ataggcacaa gacaccacaa taattattgc ctgtatgtca
3001 attattattt taaaatattg ttgtatttac ttaatgtctt taatgcattt gcccaatatt
3061 ttacattgtt actgctcaga ggtattcctt tattatgtgg ttagcatagg ttatactttg
3121 ctgacgattc acattttatt agtttggtta tgttttgtcc ttttaaaaca ttttcttttg
3181 agatgggggt cttgctctgt tgcccacgca ggagtgcagt ggcatgctct cagctcactg
3241 cagccctgac tgcctaggct ccagcaatct tcttacgtca gcctccagag tagctgggac
3301 cgcaggcact tgccaccacg ccccactaaa aattttttaa attgttgcct ttcttgaagt
3361 gttctctgcc tgtctttgtc acaaaatttc atttttctca tagttaattt catctctccg
3421 gtaagatttt attggtgttt cttttataac tttgcagttc ttacaccgtt tggtgatttt
3481 catgtttctt agaaacttta aacctttaac ttcaaacatt aaaatacaag tcttttaagt
3541 acatgagtgc ttagaaatgt acataatgtt tatatacact tatgccttac attaaagtcc
3601 aatatgagaa atacatgttt aacattcaat aataatttta aaaatttgag aaataaactc
3661 tcataaatgc aaaaaaaaaa aaaaaaaaa
//