LOCUS AF311287 2132 bp mRNA linear HUM 10-JAN-2001
DEFINITION Homo sapiens caspase recruitment domain protein 9 mRNA, complete
cds.
ACCESSION AF311287
VERSION AF311287.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2132)
AUTHORS Bertin,J., Guo,Y., Wang,L., Srinivasula,S.M., Jacobson,M.D.,
Poyet,J.-L., Merriam,S., Du,M.Q., Dyer,M.J.S., Robison,K.E.,
DiStefano,P.S. and Alnemri,E.S.
TITLE CARD9 is a novel caspase recruitment domain-containing protein that
interacts with BCL10/CLAP and activates NF-kappa B
JOURNAL J. Biol. Chem. 275 (52), 41082-41086 (2000)
PUBMED 11053425
REFERENCE 2 (bases 1 to 2132)
AUTHORS Bertin,J.
TITLE Direct Submission
JOURNAL Submitted (05-OCT-2000) Neurobiology, Millennium Pharmaceuticals,
Inc., 640 Memorial Drive, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..2132
/db_xref="H-InvDB:HIT000077003"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 128..1738
/function="binds to Bcl10/CLAP and activates NF-kB"
/note="CARD9"
/codon_start=1
/product="caspase recruitment domain protein 9"
/protein_id="AAG28790.1"
/translation="MSDYENDDECWNVLEGFRVTLTSVIDPSRITPYLRQCKVLNPDD
EEQVLSDPNLVIRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYKKVTGKEPARV
FSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQER
VQRLKEECEAGSRELKRCKEENYDLAMRLAHQSEEKGAALMRNRDLQLEIDQLKHSLM
KAEDDCKVERKHTLKLRHAMEQRPSQELLWELQQEKALLQARVQELEASVQEGKLDRS
SPYIQVLEEDWRQALRDHQEQANTIFSLRKDLRQGEARRLRCMEEKEMFELQCLALRK
DSKMYKDRIEAILLQMEEVAIERDQAIATREELHAQHARGLQEKDALRKQVRELGEKA
DELQLQVFQCEAQLLAVEGRLRRQQLETLVLSSDLEDGSPRRSQELSLPQDLEDTQLS
DKGCLAGGGSPKQPFAALHQEQVLRNPHDAGLSSGEPPEKERRRLKESFENYRRKRAL
RKMQKGWRQGEEDRENTTGSDNTDTEGS"
BASE COUNT 500 a 641 c 697 g 294 t
ORIGIN
1 ccacgcgtcc ggctcctccc tccctgcagc cccgggcagc atctcccaga ggctccgcgg
61 cccaggctcc tggtgtgtct gcagtgcagg tggctcctgg aagaccctca gcctgcctgc
121 tgaggccatg tcggactacg agaacgatga cgagtgctgg aacgtcctgg agggcttccg
181 ggtgacgctc acctcggtca tcgacccctc acgcatcaca ccttacctgc ggcagtgcaa
241 ggtcctgaac cctgatgatg aggagcaggt gctcagcgac cccaacctgg tcatccgcaa
301 acggaaagtg ggtgtgctcc tggacatcct gcagcggacc ggccacaagg gctacgtggc
361 cttcctcgag agcctggagc tctactaccc gcagctgtac aagaaggtca caggcaagga
421 gccagcccgc gtcttctcca tgatcatcga cgcgtccggg gagtcaggcc tgactcagct
481 gctgatgact gaggtcatga agctgcagaa gaaggtgcag gacctgaccg cgctgctgag
541 ctccaaagat gacttcatca aggagctgcg ggtgaaggac agcctgctgc gcaagcacca
601 ggagcgtgtg cagaggctca aggaggagtg cgaggccggc agccgcgagc tcaagcgctg
661 caaggaggag aactacgacc tggccatgcg cctggcgcac cagagtgagg agaagggcgc
721 cgcgctcatg cggaaccgtg acctgcagct ggagattgac cagctcaagc acagcctcat
781 gaaggccgag gacgactgca aggtggagcg caagcacacg ctgaagctca ggcacgccat
841 ggagcagcgg cccagccagg agctgctgtg ggagctgcag caggagaagg ccctgctcca
901 ggcccgggtg caggagctgg aggcctccgt ccaggagggg aagctggaca ggagcagccc
961 ctacatccag gtactggagg aggactggcg gcaggcgctg cgggaccacc aggagcaggc
1021 caacaccatc ttctccctgc gcaaggacct ccgccagggc gaggcccgac gcctccggtg
1081 catggaggag aaggagatgt tcgagctgca gtgcctggca ctacgtaagg actccaagat
1141 gtacaaggac cgcatcgagg ccatcctgct gcagatggag gaggtcgcca ttgagcggga
1201 ccaggccata gccacgcggg aggagctgca cgcacagcac gcccggggcc tgcaggagaa
1261 ggacgcgctg cgcaagcagg tgcgggagct gggcgagaag gcggatgagc tgcagctgca
1321 ggtgttccag tgtgaggcgc agctactggc cgtggagggc aggctcaggc ggcagcagct
1381 ggagacgctc gtcctgagct ccgacctgga agatggctca cccaggaggt cccaggagct
1441 ctcactcccc caggacctgg aggacaccca gctctcagac aaaggctgcc ttgccggcgg
1501 ggggagcccg aaacagccct ttgcagctct gcaccaggag caggttttgc ggaaccccca
1561 tgacgcaggc ctgagcagcg gggagccgcc cgagaaggag cggcggcgcc tcaaagagag
1621 ttttgagaac taccgcagga agcgcgccct caggaagatg cagaaaggat ggcggcaggg
1681 ggaggaggac cgggagaaca ccacgggcag cgacaacacc gacactgagg gctcctagcc
1741 gcagcagcgc aggccccgac cagggcacac ccaccggccc ggcctgccac ccgggggtgc
1801 cgacgccctg gggcgcagac ttccccgagc cgtcgctgac ttggcctgga acgaggaatc
1861 tggtgccctg aaaggcccag ccggactgcc gggcattggg gccgtttgtt aagcggcact
1921 cattttgcgg aggccatgcg ggtgctcacc acccccatgc acacgccatc tgtgtaactt
1981 caggatctgt tctgtttcac catgtaacac acaatacatg catgcactgt attagtgtta
2041 gaaaacacag ctgcgtaaat aaacagcacg ggtgacccgc aaaaaaaaaa aaaaaaaaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//