LOCUS AF305428 2208 bp mRNA linear HUM 12-APR-2002
DEFINITION Homo sapiens apolipoprotein L1 precursor (APOL1) mRNA, complete
cds.
ACCESSION AF305428
VERSION AF305428.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2208)
AUTHORS Monajemi,H., Fontijn,R.D., Pannekoek,H. and Horrevoets,A.J.
TITLE The apolipoprotein L gene cluster has emerged recently in evolution
and is expressed in human vascular tissue
JOURNAL Genomics 79 (4), 539-546 (2002)
PUBMED 11944986
REFERENCE 2 (bases 1 to 2208)
AUTHORS Monajemi,H., Fontijn,R.D., Pannekoek,H. and Horrevoets,A.J.G.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2000) Biochemistry, Academic Medical Center,
Meibergdreef 15, Amsterdam 1105 AZ, The Netherlands
FEATURES Location/Qualifiers
source 1..2208
/db_xref="H-InvDB:HIT000076753"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q13.1"
/note="endothelial cells"
gene 1..2208
/gene="APOL1"
CDS 148..1344
/gene="APOL1"
/note="HDL-associated after secretion"
/codon_start=1
/product="apolipoprotein L1 precursor"
/protein_id="AAL09358.1"
/translation="MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDT
GDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAE
LPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRA
LADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITA
ALTGITSSTIDYGKKWWTQAQAHDLVIKSLDKLKEVKEFLGENISNFLSLAGNTYQLT
RGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVK
LTDVAPVGFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNMLNNNYKIL
QADQEL"
BASE COUNT 657 a 507 c 594 g 450 t
ORIGIN
1 attcctcggt atatcttggg gactggagga cctgtctggt tattatacag acgcataact
61 ggaggtggga tccacacagc tcagaacagc tggatcttgc tcagtctctg ccaggggaag
121 attccttgga ggaggccctg cagcgacatg gagggagctg ctttgctgag agtctctgtc
181 ctctgcatct ggatgagtgc acttttcctt ggtgtgggag tgagggcaga ggaagctgga
241 gcgagggtgc aacaaaacgt tccaagtggg acagatactg gagatcctca aagtaagccc
301 ctcggtgact gggctgctgg caccatggac ccagagagca gtatctttat tgaggatgcc
361 attaagtatt tcaaggaaaa agtgagcaca cagaatctgc tactcctgct gactgataat
421 gaggcctgga acggattcgt ggctgctgct gaactgccca ggaatgaggc agatgagctc
481 cgtaaagctc tggacaacct tgcaagacaa atgatcatga aagacaaaaa ctggcacgat
541 aaaggccagc agtacagaaa ctggtttctg aaagagtttc ctcggttgaa aagtgagctt
601 gaggataaca taagaaggct ccgtgccctt gcagatgggg ttcagaaggt ccacaaaggc
661 accaccatcg ccaatgtggt gtctggctct ctcagcattt cctctggcat cctgaccctc
721 gtcggcatgg gtctggcacc cttcacagag ggaggcagcc ttgtactctt ggaacctggg
781 atggagttgg gaatcacagc agctttgacc gggattacca gcagtaccat agactacgga
841 aagaagtggt ggacacaagc ccaagcccac gacctggtca tcaaaagcct tgacaaattg
901 aaggaggtga aggagttttt gggtgagaac atatccaact ttctttcctt agctggcaat
961 acttaccaac tcacacgagg cattgggaag gacatccgtg ccctcagacg agccagagcc
1021 aatcttcagt cagtaccgca tgcctcagcc tcacgccccc gggtcactga gccaatctca
1081 gctgaaagcg gtgaacaggt ggagagagtt aatgaaccca gcatcctgga aatgagcaga
1141 ggagtcaagc tcacggatgt ggcccctgta ggcttctttc ttgtgctgga tgtagtctac
1201 ctcgtgtacg aatcaaagca cttacatgag ggggcaaagt cagagacagc tgaggagctg
1261 aagaaggtgg ctcaggagct ggaggagaag ctaaacatgc tcaacaataa ttataagatt
1321 ctgcaggcgg accaagaact gtgaccacag ggcagggcag ccaccaggag agatatgcct
1381 ggcaggggcc aggacaaaat gcaaactttt ttttttctga gacggagtct tgctctgtcg
1441 ccaaggtgga gcttgcagtg agccgagata tcgccactgc actccagcct gggtgacaga
1501 gcgagactcc gtctcaaaaa aaaaaaaaaa aaagaatata ttgacggaag aatagagagg
1561 aggcttgaag gaaccagcaa tgagaaggcc aggaaaagaa agagctgaaa atggagaaag
1621 cccaagagtt agaacagttg gatacaggag aagaaacagc ggctccacta cagacccagc
1681 cccaggttca atgtcctccg aagaatgaag tctttccctg gtgatggtcc cctgccctgt
1741 ctttccagca tccactctcc cttgtcctcc tgggggcaca tctcagtcag gcagcggctt
1801 cctgatgatg gtcgttgggg tggttgtcat gtgatgggtc ccctccaggt tactaaaggg
1861 tgcatgtccc ctgcttgaac actgaagggc aggtggtggg ccatggccat ggtccccagc
1921 tgaggagcag gtgtccctga gaacccaaac ttcccagaga gtatgtgaga accaaccaat
1981 gaaaacagtc ccatcgctct tacccggtaa gtaaacagtc agaaaattag catgaaagca
2041 gtttagcatt gggaggaagc tcagatctct agagctgtct tgtcgccgcc caggattgac
2101 ctgtgtgtaa gtcccaataa actcacctac tcatcaaaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//