LOCUS AF305239 4356 bp mRNA linear HUM 25-OCT-2000
DEFINITION Homo sapiens Fas-interacting serine/threonine kinase 3 (FIST3)
mRNA, complete cds.
ACCESSION AF305239
VERSION AF305239.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4356)
AUTHORS Rochat-Steiner,V., Becker,K., Micheau,O., Schneider,P., Burns,K.
and Tschopp,J.
TITLE FIST/HIPK3: a Fas/FADD-interacting serine/threonine kinase that
induces FADD phosphorylation and inhibits fas-mediated Jun
NH(2)-terminal kinase activation
JOURNAL J. Exp. Med. 192 (8), 1165-1174 (2000)
PUBMED 11034606
REFERENCE 2 (bases 1 to 4356)
AUTHORS Rochat-Steiner,V., Schneider,P. and Tschopp,J.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2000) University of Lausanne, Institute of
Biochemistry, 155, ch. des Boveresses, Epalinges 1066, Switzerland
FEATURES Location/Qualifiers
source 1..4356
/db_xref="H-InvDB:HIT000076751"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
gene 1..4356
/gene="FIST3"
CDS 34..3618
/gene="FIST3"
/note="FIST3; protein kinase"
/codon_start=1
/product="Fas-interacting serine/threonine kinase 3"
/protein_id="AAG25990.1"
/translation="MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSSCVFQERNYPRTY
VNGRNFGNSHPPTKGSAFQTKIPFKRPRGHNFSLQTSAVVLKNTAGATKVIAAQAQQA
HVQAPQIGAWRNRLHFLEGPQRCGLKRKSEELDNHSSAMQIVDELSILPAMLQTNMGN
PVTVVTATTGSKQNCTTGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRG
TNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFE
MLEQNLYDFLKQNKFSPLPLKVIRPILQQVATALKKLKSLGLIHADLKPENIMLVDPV
RQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAEL
FLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCKETDMSHSGWRLKTLE
EHEAETGMKSKEARKYIFNSLDDVAHVNTVMDLEGSDLLAEKADRREFVSLLKKMLLI
DADLRITPAETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSHLNSCDTNNHNKTSL
LRPVASSSTATLTANFTKIGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFQQTL
IICPPAIQGIPATHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQTWSGRTQQM
LVPAWQQVTPLAPATTTLTSESVAGSHRLGDWGKMISCSNHYNSVMPQPLLTNQITLS
APQPVSVGIAHVVWPQPATTKKNKQCQNRSNSLQNTNIPHSAFISPKIINGKDVEEVS
CIETQDNQNSEGEARNCCETSIRQDSDSSVSDKQRQTIIIADSPSPAVSVITISSDTD
EEETSQRHSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPN
SMSDEEQESSCDTVDGSPTSDSSGHDSPFAESTFVEDTHENTELVSSADTETKPAVCS
VVVPPVELENGLNADEHMANTDSICQPLIKGRSAPGRLNQPSAVGTRQQKLTSAFQQQ
HLNFSQVQHFGSGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGN
THLGGQPTLLPYPSSATLSSAAPVAHLLASPCTSRPMLKHPTYNISHPSGIVHQVPVG
LNPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM"
BASE COUNT 1299 a 916 c 923 g 1218 t
ORIGIN
1 cgaagaggag agagcgcggg cctctaggaa ggtatggcct cacaagtctt ggtctaccca
61 ccatatgttt atcaaactca gtcaagtgcc ttttgtagtg tgaagaaact caaagtagag
121 ccaagcagtt gtgtattcca ggaaagaaac tatccacgga cctatgtgaa tggtagaaac
181 tttggaaatt ctcatcctcc cactaagggt agtgcttttc agacaaagat accatttaag
241 agacctcgag gacacaactt ttcattgcag acaagtgctg ttgttttgaa aaacactgca
301 ggtgctacaa aggtcatagc agctcaggca cagcaagctc acgtgcaggc acctcagatt
361 ggggcgtggc gaaacagatt gcatttccta gaaggccccc agcgatgtgg attgaagcgc
421 aagagtgagg agttggataa tcatagcagc gcaatgcaga ttgtcgatga attgtccata
481 cttcctgcaa tgttgcaaac caacatggga aatccagtga cagttgtgac agctaccaca
541 ggatcaaaac agaattgtac cactggagaa ggtgactatc agttagtaca gcatgaagtc
601 ttatgctcca tgaaaaatac ttacgaagtc cttgattttc ttggtcgagg cacgtttggc
661 caggtagtta aatgctggaa aagagggaca aatgaaattg tagcaatcaa aattttgaag
721 aatcatcctt cttatgcccg tcaaggtcaa atagaagtga gcatattagc aaggctcagt
781 actgaaaatg ctgatgaata taactttgta cgagcttatg aatgctttca gcaccgtaac
841 catacttgtt tagtctttga gatgctggaa caaaacttgt atgactttct gaaacaaaat
901 aaatttagtc ccctgccact aaaagtgatt cggcccattc ttcaacaagt ggccactgca
961 ctgaaaaaat tgaaaagtct tggtttaatt catgctgatc tcaagccaga gaatattatg
1021 ttggtggatc ctgttcggca gccttacagg gttaaagtaa tagactttgg gtcggccagt
1081 catgtatcaa agactgtttg ttcaacatat ctacaatctc ggtactacag agctccagag
1141 attatattgg ggttgccatt ttgtgaagcc atagacatgt ggtcattggg atgtgtgatt
1201 gcagaattat ttcttggatg gccgctctac ccaggagcct tggagtatga tcagattcga
1261 tacatttctc agactcaagg tttgccagga gaacagttgt taaatgtggg tactaaatcc
1321 acaagatttt tttgcaaaga aacagatatg tctcattctg gttggagatt aaagacattg
1381 gaagagcatg aggcagagac aggaatgaag tctaaagaag ccagaaaata cattttcaac
1441 agtctggatg atgtagcgca tgtgaacaca gtgatggatt tggaaggaag tgatcttttg
1501 gctgagaaag ctgatagaag agaatttgtt agtctgttga agaaaatgtt gctgattgat
1561 gcagatttaa gaattactcc agctgagacc ctgaaccatc cttttgttaa tatgaaacat
1621 cttctagatt tccctcatag caaccatgta aagtcctgtt ttcatattat ggatatttgt
1681 aagtcccacc taaattcatg tgacacaaat aatcacaaca aaacttcact tttaagacca
1741 gttgcttcaa gcagtactgc tacactgact gcaaatttta ctaaaatcgg aacattaaga
1801 agtcaggcat tgaccacatc tgctcattca gttgtgcacc atggaatacc tctgcaggca
1861 ggaactgctc agtttggttg tggtgatgct tttcagcaga cattgattat ctgtccccca
1921 gctattcaag gtattcctgc aacacatggt aaacccacca gttattcaat aagggtagat
1981 aatacagttc cacttgtaac tcaggcccca gctgtgcagc cactacagat ccgaccagga
2041 gttctttctc agacgtggtc tggtagaaca cagcagatgc tggtgcctgc ctggcaacag
2101 gtgacacccc tggctcctgc tactactaca ctaacttctg agagtgtggc tggttcacac
2161 aggcttggag actgggggaa gatgatttca tgcagcaatc attataactc agtgatgccg
2221 cagcctcttc tgaccaatca gataacttta tctgcccctc agccagttag tgtggggatt
2281 gcacatgttg tctggcctca gcctgccact accaagaaaa ataaacagtg ccagaacagg
2341 agtaattcat tacagaatac caatatccca cattcagcat ttatttctcc aaagataatt
2401 aatgggaaag atgtcgagga agtaagttgt atagaaacac aggacaatca gaactcagaa
2461 ggagaggcaa gaaattgctg tgaaacatct atcagacagg actctgattc atcagtttca
2521 gacaaacagc ggcaaaccat cattattgcc gactccccga gtcctgcagt gagtgtcatc
2581 actatcagca gtgacactga tgaggaagag acttcccaga gacattcact cagagaatgt
2641 aaaggtagtc tagattgtga agcttgccag agcactttga atattgatcg gatgtgttca
2701 ttaagtagtc ctgatagtac tctgagtacc agctcctcag ggcagtccag cccatccccc
2761 tgcaagagac cgaatagtat gtcagatgaa gagcaagaaa gtagttgtga tacggtggat
2821 ggctctccga catctgactc ttccgggcat gacagtccat ttgcagagag cacttttgtg
2881 gaggacactc atgaaaacac agaattggta tcctctgctg acacagaaac caagccagct
2941 gtctgttctg ttgtggtgcc accagtggaa ctagaaaatg gcttaaatgc cgatgagcat
3001 atggcaaaca cagattctat atgccagcca ttaataaaag gacgatctgc ccctggaaga
3061 ttaaaccagc cttctgcagt gggtactcgt cagcaaaaat tgacatcagc attccagcag
3121 cagcatttga acttcagtca ggttcagcac tttggatctg ggcatcaaga gtggaatgga
3181 aactttgggc acagaagaca gcaagcttat attcctacta gtgttaccag taatccattc
3241 actctttctc atggaagtcc caatcacaca gcagtgcatg cccacctggc tggaaataca
3301 cacctcggag gacagcctac tctacttcca tacccatcat cagccaccct cagtagtgct
3361 gcaccagtgg cccacctgtt agcctctccg tgtacctcaa gacctatgtt aaagcatcca
3421 acttataata tctcccatcc cagtggcata gttcaccaag tcccagtggg cttaaatccc
3481 cgtctgttac catccccaac cattcatcag actcagtaca aaccaatctt cccaccacat
3541 tcttacattg cagcatcacc tgcatatact ggatttccac tgagtccaac aaaactcagc
3601 cagtatccat atatgtgaaa aacagtatat tggggaagct caatgataca aacatttgat
3661 taaaaataaa aacatggtat ttaatattag ccatggcaca agaaaattat ttttggaatc
3721 atgtagactt gggtgcaatt taaacaactt tgagctttaa aaactcactt ttgatgtgtt
3781 ttgcacattt ggtataactt gtctttggtc atgttatctt cttatgtagt aactctagac
3841 aggtgactta tgggagcaga agtccagttt tgctcctgct attttttata aattgccttc
3901 taactagtgc aagacacgtc tacatttggg aagccattct gtgtacagac ttagagcaac
3961 agatgcacat atgtcagaat tacagcatac aagtgaattg tattatccgt gtcttagtgt
4021 ataaatgttg ggtcacttac ctaagaaatt gagctattgt tctttacatt tgcatgtgtc
4081 ttttgcatgg gcaaaatgtt gcctagactt tgctcttaaa tgttgttcta ataatctcag
4141 ctgcattgta aaccgttcct acacatagtg ccttaaatat ttgaggttgt taatgttatt
4201 acctatatat aaatgttgag gactgcagca cttaaaattc agacctacta tttagtttcc
4261 ttttgatagc gtaatgttca tttttgtttt tgtgtggtat gatttcaggt agtagctgtt
4321 tttttcctta ttaagagggc agcatgtttg ctatag
//