LOCUS AF305210 2209 bp mRNA linear HUM 22-JAN-2001
DEFINITION Homo sapiens concentrative Na+-nucleoside cotransporter hCNT3
(CNT3) mRNA, complete cds.
ACCESSION AF305210
VERSION AF305210.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2209)
AUTHORS Ritzel,M.W.L., Ng,A.M.L., Yao,S.Y.M., Graham,K., Loewen,S.K.,
Smith,K.M., Ritzel,R.G., Mowles,D.A., Carpenter,P., Chen,X.-Z.,
Karpinski,E., Hyde,R.J., Baldwin,S.A., Cass,C.E. and Young,J.D.
TITLE Molecular identification and characterization of novel human and
mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3
and mCNT3) broadly selective for purine and pyrimidine nucleosides
(system cib)
JOURNAL J. Biol. Chem. 276 (4), 2914-2927 (2001)
PUBMED 11032837
REFERENCE 2 (bases 1 to 2209)
AUTHORS Ritzel,M.W.L., Ng,A.M.L., Yao,S.Y.M., Graham,K., Loewen,S.K.,
Smith,K.M., Ritzel,R.G., Mowles,D.A., Carpenter,P., Chen,X.-Z.,
Karpinski,E., Hyde,R.J., Baldwin,S.A., Cass,C.E. and Young,J.D.
TITLE Direct Submission
JOURNAL Submitted (12-SEP-2000) Physiology, University of Alberta, 7-25
Medical Sciences Building, Edmonton, AB T6G2H7, Canada
FEATURES Location/Qualifiers
source 1..2209
/db_xref="H-InvDB:HIT000076746"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q22.2"
/cell_line="myeloid HL-60"
gene 1..2209
/gene="CNT3"
CDS 93..2168
/gene="CNT3"
/note="broad substrate specificity for purines and
pyrimidines (system cib)"
/codon_start=1
/product="concentrative Na+-nucleoside cotransporter
hCNT3"
/protein_id="AAG22551.1"
/translation="MELRSTAAPRAEGYSNVGFQNEENFLENENTSGNNSIRSRAVQS
REHTNTKQDEEQVTVEQDSPRNREHMEDDDEEMQQKGCLERRYDTVCGFCRKHKTTLR
HIIWGILLAGYLVMVISACVLNFHRALPLFVITVAAIFFVVWDHLMAKYEHRIDEMLS
PGRRLLNSHWFWLKWVIWSSLVLAVIFWLAFDTAKLGQQQLVSFGGLIMYIVLLFLFS
KYPTRVYWRPVLWGIGLQFLLGLLILRTDPGFIAFDWLGRQVQTFLEYTDAGASFVFG
EKYKDHFFAFKVLPIVVFFSTVMSMLYYLGLMQWIIRKVGWIMLVTTGSSPIESVVAS
GNIFVGQTESPLLVRPYLPYITKSELHAIMTAGFSTIAGSVLGAYISFGVPSSHLLTA
SVMSAPASLAAAKLFWPETEKPKITLKNAMKMESGDSGNLLEAATQGASSSISLVANI
AVNLIAFLALLSFMNSALSWFGNMFDYPQLSFELICSYIFMPFSFMMGVEWQDSFMVA
RLIGYKTFFNEFVAYEHLSKWIHLRKEGGPKFVNGVQQYISIRSEIIATYALCGFANI
GSLGIVIGGLTSMAPSRKRDIASGAVRALIAGTVACFMTACIAGILSSTPVDINCHHV
LENAFNSTFPGNTTKVIACCQSLLSSTVAKGPGEVIPGGNHSLYSLKGCCTLLNPSTF
NCNGISNTF"
BASE COUNT 560 a 515 c 532 g 602 t
ORIGIN
1 ctaaatgaag agcgcttggg acctgaacaa ccagcagcga tacccaggta caaaggacct
61 ccagaccaga gccagccagc agcaaaaaga gcatggagct gaggagtaca gcagccccca
121 gagctgaggg ctacagcaac gtgggcttcc agaatgaaga aaactttctt gagaacgaga
181 acacatcagg aaacaactca ataagaagca gagctgtgca aagcagggag cacacaaaca
241 ccaaacagga tgaagaacag gtcacagttg agcaggattc tccaagaaac agagaacaca
301 tggaggatga tgatgaggag atgcaacaaa aagggtgttt ggaaaggagg tatgacacag
361 tatgtggttt ctgtaggaaa cacaaaacaa ctcttcggca catcatctgg ggcattttat
421 tagcaggtta tctggttatg gtgatttcgg cctgtgtgct gaactttcac agagcccttc
481 ctctttttgt gatcaccgtg gctgccatct tctttgttgt ctgggatcac ctgatggcca
541 aatacgaaca tcgaattgat gagatgctgt ctcctggcag aaggcttcta aacagccatt
601 ggttctggct gaagtgggtg atctggagct ccctggtcct agcagttatt ttctggttgg
661 cctttgacac tgccaaattg ggtcaacagc agctggtgtc cttcggtggg ctcataatgt
721 acattgtcct gttatttcta ttttccaagt acccaaccag agtttactgg agacctgtct
781 tatggggaat cgggctacag tttcttcttg ggctcttgat tctaaggact gaccctggat
841 ttatagcttt tgattggttg ggcagacaag ttcagacttt tctggagtac acagatgctg
901 gtgcttcatt tgtctttggt gagaaataca aagaccactt ctttgcattt aaggtcctgc
961 cgatcgtggt tttcttcagc actgtgatgt ccatgctgta ctacctggga ctgatgcagt
1021 ggattattag aaaggttgga tggatcatgc tagttactac gggatcatct cctattgaat
1081 ctgtagttgc ttctggcaat atatttgttg gacaaacgga gtctccactg ctggtccgac
1141 catatttacc ttacatcacc aagtctgaac tccacgccat catgaccgcc gggttctcta
1201 ccattgctgg aagcgtgcta ggtgcataca tttcttttgg ggttccatcc tcccacttgt
1261 taacagcgtc agttatgtca gcacctgcgt cattggctgc tgctaaactc ttttggcctg
1321 agacagaaaa acctaaaata accctcaaga atgccatgaa aatggaaagt ggtgattcag
1381 ggaatcttct agaagctgca acacagggag catcctcctc catctccctg gtggccaaca
1441 tcgctgtgaa tctgattgcc ttcctggccc tgctgtcttt tatgaattca gccctgtcct
1501 ggtttggaaa catgtttgac tacccacagc tgagttttga gctaatctgc tcctacatct
1561 tcatgccctt ttccttcatg atgggagtgg aatggcagga cagctttatg gttgccagac
1621 tcataggtta taagaccttc ttcaatgaat ttgtggctta tgagcacctc tcaaaatgga
1681 tccacttgag gaaagaaggt ggacccaaat ttgtaaacgg tgtgcagcaa tatatatcaa
1741 ttcgttctga gataatcgcc acttacgctc tctgtggttt tgccaatatc gggtccctag
1801 gaatcgtgat cggcggactc acatccatgg ctccttccag aaagcgtgat atcgcctcgg
1861 gggcagtgag agctctgatt gcggggaccg tggcctgctt catgacagcc tgcatcgcag
1921 gcatactctc cagcactcct gtggacatca actgccatca cgttttagag aatgccttca
1981 actccacttt ccctggaaac acaaccaagg tgatagcttg ttgccaaagt ctgttgagca
2041 gcactgttgc caagggtcct ggtgaagtca tcccaggagg aaaccacagt ctgtattctt
2101 tgaagggctg ctgcacattg ttgaatccat cgacctttaa ctgcaatggg atctctaata
2161 cattttgagg tcagccactt ctccagtgga actctgaagt acagatgct
//