LOCUS AF303581 2994 bp mRNA linear HUM 16-APR-2001
DEFINITION Homo sapiens SPIN90 mRNA, complete cds.
ACCESSION AF303581
VERSION AF303581.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2994)
AUTHORS Lim,C.S., Park,E.S., Kim,D.J., Song,Y.H., Eom,S.H., Chun,J.S.,
Kim,J.H., Kim,J.K., Park,D. and Song,W.K.
TITLE SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor
protein that is developmentally regulated during cardiac myocyte
differentiation
JOURNAL J. Biol. Chem. 276 (16), 12871-12878 (2001)
PUBMED 11278500
REFERENCE 2 (bases 1 to 2994)
AUTHORS Lim,C.S., Park,E.S. and Song,W.K.
TITLE Direct Submission
JOURNAL Submitted (08-SEP-2000) Life Science, Kwangju Institute of Science
and Technology, 1 Oryong-dong, Puk-gu, Kwangju 500-712, South Korea
FEATURES Location/Qualifiers
source 1..2994
/db_xref="H-InvDB:HIT000076712"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21"
CDS 66..2234
/note="adaptor protein; SH3 protein interacting with Nck;
90 kDa"
/codon_start=1
/product="SPIN90"
/protein_id="AAK09094.1"
/translation="MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGE
TGYVPPAYLRRLQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKE
TLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGL
YQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSV
SSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEV
ATGTTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAELMELVRRNTGLSHELCRVA
IGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARR
KDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQM
EHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALIL
AMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLP
AADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGS
PATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPD
LQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS"
misc_feature 75..224
/note="Region: SH3 domain"
misc_feature 576..611
/note="proline-rich Nck-binding"
misc_feature 795..812
/note="proline-rich Nck-binding"
BASE COUNT 666 a 958 c 808 g 562 t
ORIGIN
1 tccgggcctg gcgttgtggc gccgcagccc ttgccacctt ccctgcacct gccctgcccg
61 gcctcatgta ccgcgcgctg tacgcgttcc gctcggcgga gcccaacgcg ctggcgttcg
121 ccgcgggcga gaccttcctg gtgctagagc gaagcagcgc gcactggtgg ctggccgcgc
181 gggcgcgcag tggtgagacg ggctacgtgc cgccagccta cctgcgccgc ctgcagggcc
241 tggagcagga tgtcctccag gccattgacc gggccatcga ggctgtacac aacacagcca
301 tgcgggatgg tggcaagtac agcctggaac agcgtggagt cctccagaag ctgatccacc
361 accggaaaga gaccctgtca cgcagaggcc cttcagcctc cagtgttgca gttatgacct
421 catcaaccag tgaccaccac ttggatgctg ctgcagccag gcagcccaat ggggtgtgtc
481 gagctgggtt cgagcggcag cacagcctac ccagttctga gcatcttggg gcagatggag
541 gcctctacca gatcccactt ccatcttccc agatcccacc acagcctcgc cgagcagcac
601 ccaccacacc gcccccacca gtgaagcgcc gagaccgcga ggccctgatg gcctctggga
661 gtggtggcca caacaccatg ccctccgggg gtaactctgt gtccagcggc tcctcagtca
721 gcagcacctc cctggacacg ctctatacca gctccagccc atctgaacca ggctccagct
781 gctcacccac acccccacct gtgccccgcc gaggcaccca caccaccgtg tcccaagtcc
841 agccccctcc ctccaaggca tcagcacctg aaccccctgc agaagaagaa gtggcaactg
901 gtacaacctc agcctctgat gacctggaag ccctgggtac actgagcctg gggaccacag
961 aggagaaggc agcagctgag gcggctgtgc ccaggaccat tggggccgag ctgatggagc
1021 tggtgcggag aaacactggc ctgagccacg aattatgccg ggtggccatc ggcatcatag
1081 tgggtcacat ccaggcctcg gtgccggcca gctcaccagt catggagcag gtcctcctct
1141 cactcgtaga gggcaaggac ctcagcatgg ccctgccctc agggcaggtc tgccacgacc
1201 agcagaggct ggaggtgatc tttgcagacc tggctcgccg gaaggacgac gcccagcagc
1261 gcagttgggc actatatgag gatgagggtg tcatccgctg ctacctagag gagctgctgc
1321 atattctgac tgatgcagac cctgaagttt gcaagaaaat gtgcaagaga aacgagttcg
1381 agtctgtcct ggccttggtg gcctattacc aaatggaaca ccgagcatca ctgcggctgc
1441 tgctcctcaa gtgctttggc gccatgtgca gcctggatgc agccatcatc tccacgcttg
1501 tgtcatccgt gctgcctgta gagctggcga gggacatgca gacagacacg caggaccacc
1561 agaaactctg ttactctgcc ctcatcctgg ccatggtctt ctccatggga gaggcagtgc
1621 cctatgcaca ctatgagcac ctgggcacgc ctttcgccca gttcctactg aacatcgtcg
1681 aggatgggct gcccttggac accacagagc agctgccgga cctctgcgtg aacctgcttc
1741 tggctctcaa cctgcacctg ccagctgctg accagaatgt catcatggct gccctgagca
1801 aacacgccaa tgtcaagatc ttctccgaga agctgttgtt gctcctgaac agaggggatg
1861 accctgtgcg catcttcaaa catgagccac agccaccaca ctctgtcctc aagttcctgc
1921 aggacgtgtt tggcagcccg gccacagctg ccatcttcta ccacacagac atgatggctc
1981 tcattgacat cactgtgcgg cacatcgcag acctgtcacc aggagacaag ctgcgcatgg
2041 agtacctctc cctgatgcat gctatagtcc gcaccacacc ctacctgcag caccgccacc
2101 ggctacccga cctgcaggcc atactgcgac gcatcctgaa tgaggaggag acctcacccc
2161 agtgccagat ggaccgcatg attgtccgag agatgtgcaa ggaattcctg gtgctggggg
2221 aggctcccag ctagcacctt gctgtcctcc cttccctgca gctccagtca gtgtgcaggg
2281 gactcagggg cttggcccta agaatgtttt gcactgacag tgggagggga taaggtggca
2341 gaaggaacct gagcaggacc cccacctgaa gtagaactta agagaggggc caagtgtagg
2401 attggggacc atggtctggg agctgttctg gggcaggggg aatatgcaag ctaaagcccc
2461 tctataccct ggtaggcttc ctcttcagca tgcccccctc ttcaccccac acccatgtgt
2521 acactcagag tcctgctgcc gctccaggct ggaccagacc cccatcccca cccctcctgg
2581 tctgtatcct gggcctcagc aagccatgcc cctggggtga ggggaggcat ctcccaccag
2641 ctctattctt tgccttagct ttgcagtgag tgctgctcat gtcctcccct ccacccgcac
2701 atgggggtcg ctgcccttca ctcctacccc cagaggcctt ggccaagctg ctgctttgaa
2761 agcgggatct tggagacagg ccatccatcc tggagcctca tggaacagga tgatggcact
2821 gagaaagcca atgaccgaat ctcttttctc tgtaaaaatg tagactgaaa agccatgtgt
2881 attttcctat gtgctgtagc tctcctttgg aaataaatca caggcatctg gaaaaaaaaa
2941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//