LOCUS AF300717 3113 bp mRNA linear HUM 05-JUN-2001
DEFINITION Homo sapiens NUB1 (NUB1) mRNA, complete cds.
ACCESSION AF300717
VERSION AF300717.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3113)
AUTHORS Kito,K., Yeh,E.T. and Kamitani,T.
TITLE NUB1, a NEDD8-interacting protein, is induced by interferon and
down-regulates the NEDD8 expression
JOURNAL J. Biol. Chem. 276 (23), 20603-20609 (2001)
PUBMED 11259415
REFERENCE 2 (bases 1 to 3113)
AUTHORS Kito,K., Yeh,E.T.H. and Kamitani,T.
TITLE Direct Submission
JOURNAL Submitted (28-AUG-2000) Cardiology, University of Texas, M.D.
Anderson Cancer Center, 1515 Fannin, Box 449, Houston, TX 77030,
USA
FEATURES Location/Qualifiers
source 1..3113
/db_xref="H-InvDB:HIT000076645"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="heart"
gene 1..3113
/gene="NUB1"
CDS 78..1883
/gene="NUB1"
/note="interferon-inducible nucleoprotein;
NEDD8-interacting protein; downregulates NEDD8 expression"
/codon_start=1
/product="NUB1"
/protein_id="AAK21001.1"
/translation="MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQ
YSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLE
TRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQ
SEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQ
TGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDT
VDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGK
EKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQE
ARLGLRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQ
QILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLA
AQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIP
EHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKKN"
BASE COUNT 911 a 693 c 776 g 733 t
ORIGIN
1 ccggaatgaa aacaaacggc ggccgctgcc gcatccgggc actctgctgg tcgcggcggg
61 agtggcgtgg cgcagggatg gcacaaaaga aatatcttca agcaaaattg acccagtttt
121 taagggaaga caggattcaa ctttggaaac ctccatatac agatgaaaat aaaaaagttg
181 gtttggcatt aaaggacctt gctaagcagt actctgacag actagaatgc tgtgaaaatg
241 aagtagaaaa ggtaatagaa gaaatacgtt gcaaggcaat tgagcgtgga acaggaaatg
301 acaattatag aacaacggga attgctacaa tcgaggtgtt tttaccacca agactaaaaa
361 aagataggaa aaacttgttg gagacccgat tgcacatcac tggcagagaa ctgaggtcca
421 aaatagctga aacctttgga cttcaagaaa attatatcaa aattgtcata aataagaagc
481 aactacaact agggaaaacc cttgaagaac aaggcgtggc tcacaatgtg aaagcgatgg
541 tgcttgaact aaaacaatct gaagaggacg cgaggaaaaa cttccagtta gaggaagagg
601 agcaaaatga ggccaaactc aaagaaaaac aaattcagag gaccaagaga ggactagaaa
661 tactggcaaa gagagcagca gagacagtgg tggatccaga aatgacaccg tacttagaca
721 tagctaacca gacaggcaga tcaatcagaa ttcccccatc agaaagaaaa gcccttatgt
781 tagctatggg atatcatgag aagggcagag ctttcctgaa aagaaaagaa tatggaatag
841 ccttgccatg tctgttggac gctgacaaat atttctgtga gtgttgcaga gagctgctgg
901 acacagtgga taactatgcc gtcctccagc tggatatagt gtggtgttac ttccgcctgg
961 aacagctgga atgccttgat gatgcagaaa aaaaattaaa cttggcccag aaatgcttta
1021 aaaattgtta cggagaaaat catcagagac tggtccacat aaaaggaaat tgtgggaaag
1081 agaaggtact gtttctaaga ctctacttac ttcaagggat ccgaaactat cacagtggaa
1141 atgatgtaga ggcttatgag tatcttaaca aggcacgtca gctctttaaa gagctatata
1201 ttgatccatc aaaagtggac aatttgttgc agttggggtt tactgcccag gaagcccggc
1261 ttggcctgag ggcgtgtgat gggaacgtgg atcatgcggc cactcatatt accaaccgca
1321 gagaggaact ggcccaaata aggaaggagg aaaaagagaa gaaaagacgc cgcctcgaga
1381 acatcaggtt tctgaaaggg atgggctact ccacgcacgc ggcccagcag attctgctca
1441 gcaatcctca gatgtggtgg ttaaatgatt ccaatcctga aaccgacaac cgtcaagaaa
1501 gtccttccca ggaaaacatt gaccgattgg tgtacatggg ttttgatgca ctcgtggccg
1561 aagctgcgct gagagtgttc agaggcaacg tccagctggc cgcccagacc cttgctcaca
1621 acggaggaag cctgcctccc gagctgccgc tgtcgccaga agactctttg tccccgccag
1681 ccacgtcccc ttctgactcc gcaggaacct ctagtgcctc aacagacgaa gacatggaga
1741 cagaggccgt caatgagata ctggaagaca ttccagagca tgaggaagac tatcttgact
1801 caactctgga agatgaagaa attattattg cagagtacct atcctatgta gaaaatagga
1861 agtcagcaac aaagaaaaac taaataatga acagaaatag cgctaatttt ctgcttataa
1921 atgctatcat tatgaaaagg ctaatgcagc tctttctgtt cttacttttt atctgaatta
1981 caagtcctct ttgggtgtag gagggggtgg gcaggggaca agtccaggag gggtcccagg
2041 gccttcatgc atggtctcgg ggaagaagct tcctctggcc tggcgcaggc cgttccatct
2101 gcctcccagg tctgcgtccc ataacccttt ccccagcttg gtgttttacc ccgaaacagg
2161 aaggaacagg ggtcctgtag aacaggggtc ctggggaagg tgtccagggc agggtcctgg
2221 gaagggtgtc ccgactgctt cctctccagc tgtggctcca tctgcccagc ttgcctgcct
2281 cctgcaccca ctgccctgac cttcctgctt cccacgctgc catctctgcc agggtgccac
2341 atgggttcct gtgccaccct ttccccgccc ctcaaatcgt cctttaagtc ttccttccaa
2401 gtgctgtggg gcataacgat gaggcgctgg ccttgggggc cacaccaggt cgcagcaaat
2461 ggcttcagcc tgggacgcca gtgttttatg ctcttagttc agtaaaatac gcccccgaaa
2521 ttcaagattg agtgtcaggc tttatatata ttcagcattc ctcattacag aaatcttcta
2581 ttgaatggga aaggtttaaa tgctaaccaa agcaatttat ttttaattaa tatttttaga
2641 ctctgtgctg tcatactgaa ctcactgcta gctaagagac ctatcagaga tttagatata
2701 ttttctccag gttttttgtg ggttttcttt gttgttgttg ttgttctagc catgtgacag
2761 aggctctttc taaaagtatg tagttcgctg tgtgtcggct ccagcagtaa ccgtcctcac
2821 tgcgccacgc actcctctgt agatgtgtgc ccagtgggag ttccttccag ccccaggacc
2881 gcagcagcag ccaggtgccg agtggattga gtgccaggtg catccaagac tttccctccc
2941 ttccagaagg cactgactga agacaggatg gatcatgcgg agccggctga aatgctccaa
3001 ctttttcaaa gtgtgggtgg tccagtttgg actgatggga atcttcttgt cattcttttt
3061 aaacggatga taccgatgga aataaaaggt gggaaatata ttcaaaaaaa aaa
//