LOCUS AF298880 5231 bp mRNA linear HUM 08-JAN-2002
DEFINITION Homo sapiens exportin 5 mRNA, complete cds.
ACCESSION AF298880
VERSION AF298880.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5231)
AUTHORS Brownawell,A.M. and Macara,I.G.
TITLE Exportin-5, a novel karyopherin, mediates nuclear export of
double-stranded RNA binding proteins
JOURNAL J. Cell Biol. 156 (1), 53-64 (2002)
PUBMED 11777942
REFERENCE 2 (bases 1 to 5231)
AUTHORS Brownawell,A.M. and Macara,I.G.
TITLE Direct Submission
JOURNAL Submitted (24-AUG-2000) Center for Cell Signaling, University of
Virginia, P.O. Box 800577, Charlottesville, VA 22908, USA
FEATURES Location/Qualifiers
source 1..5231
/db_xref="H-InvDB:HIT000076628"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
CDS 64..3678
/note="putative transport receptor; Ran-binding protein;
similar to Msn5p"
/codon_start=1
/product="exportin 5"
/protein_id="AAG17907.1"
/translation="MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKC
PICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGT
LNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRL
AEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQ
ANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAECLLIAVS
RKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLC
ALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLA
IIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLA
CRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTL
FLESVITQMFRTLNREEIPVNDGIELLQMVLNFDTKDPLILSCVLTNVSALFPFVTYR
PEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFD
MLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLS
QDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRARMSFCVYSILGVVKRTCWPTD
LEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEP
FTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGP
SMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLVLFCPPEHYEALVSP
ILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDL
ITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLI
TAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGLQMHGQHDG
CMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRR
KDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLATIFEP
"
BASE COUNT 1361 a 1262 c 1248 g 1360 t
ORIGIN
1 agctgtcgtg cctcgtggtc ccgggactgc agtggtgtgc gctctcggcg cgtggcgcta
61 ggcatggcga tggatcaagt aaacgcgctg tgcgagcagc tggtgaaagc ggtgacggtc
121 atgatggacc ccaactccac ccagcgctac cggctggaag ccctcaagtt ttgtgaggag
181 tttaaagaaa agtgtcctat ctgtgtcccc tgtggcttga ggttggctga gaaaacacaa
241 gttgccatcg tcagacattt tggccttcag atcctggaac acgttgtcaa gtttcggtgg
301 aacggcatgt ctcgattgga gaaggtgtat ctgaagaaca gtgtcatgga gctgattgca
361 aatggaacat tgaacatttt ggaagaggag aaccatatta aagatgctct gtctcgaatt
421 gtagtggaaa tgatcaagcg agagtggcca cagcattggc ctgacatgct aatagaattg
481 gacactcttt ccaaacaagg ggaaacacag acagaattgg tgatgtttat ccttttgcga
541 ctggcagagg atgtagtgac ttttcagaca cttccccctc aaagaagaag ggacatccag
601 caaacattaa cccagaacat ggaaaggatc ttcagttttc tgcttaacac acttcaagaa
661 aatgtaaaca agtatcagca agtgaagaca gatacttctc aggagtcaaa ggcgcaagca
721 aactgtcgag taggagttgc agcactgaat actctagcag gctatattga ctgggtgtct
781 atgagtcaca tcactgctga aaactgtaaa ctcctggaga tactgtgttt gctgttgaat
841 gaacaggaac ttcagttggg agccgctgag tgtcttctca ttgcagtcag cagaaaaggc
901 aagttggaag accggaagcc cttgatggtc ttatttggag atgttgccat gcattatata
961 ctctccgccg cacagactgc tgatggagga ggtttggtag aaaaacacta cgtctttctg
1021 aagaggctct gtcaggtgtt gtgtgcgctg ggcaatcagc tgtgtgcatt gctgggtgca
1081 gattctgatg tagaaacacc atcaaacttt ggaaaatacc tggaatcttt tcttgctttc
1141 acaacccatc caagtcagtt tctacgctct tcaactcaga tgacttgggg agccctcttc
1201 aggcatgaaa tcctgtcccg tgatcctttg ctattagcaa taataccaaa atatcttcgt
1261 gcttccatga ctaacttggt caagatgggc tttccttcta aaacagacag ccctagctgt
1321 gaatattctc ggtttgattt tgatagcgat gaggacttca atgctttctt caactcctcc
1381 cgagcacaac aaggagaggt gatgaggttg gcatgtcgtt tggatcccaa aactagcttc
1441 cagatggctg gggagtggct aaagtatcaa ctatcaactt ttcttgatgc tggttctgtg
1501 aattcttgtt ctgcagttgg aactggagaa ggaagcctct gttccgtctt ctcaccttca
1561 ttcgtgcagt gggaagccat gactcttttt ttggaaagtg ttatcaccca gatgtttcga
1621 acactaaata gagaagaaat tcctgttaat gatggaatag agctattgca gatggttctg
1681 aactttgata ccaaggatcc cctcatcctg tcctgcgtcc ttactaatgt ctctgcactc
1741 tttccatttg tcacctacag accagagttc ctgccccagg tcttctctaa gctattttca
1801 tctgtcactt ttgaaactgt tgaagaaagt aaggccccca gaacccgggc agtgaggaat
1861 gtgaggaggc atgcttgttc ctccatcatc aagatgtgtc gtgactaccc ccagcttgtg
1921 ctgcccaatt ttgacatgct ttataaccat gtgaagcaac tcctctccaa tgagctactc
1981 ctgacacaaa tggagaagtg tgccctcatg gaagccctgg ttctcattag caaccaattt
2041 aagaactacg agcgtcagaa ggtgttccta gaggagctga tggcaccagt ggccagcatc
2101 tggctttctc aagacatgca cagagtgctg tcagatgttg atgctttcat tgcgtatgtg
2161 ggtacagatc agaagagctg tgacccaggc ctggaggatc cgtgtggctt aaaccgtgca
2221 cgaatgagct tttgtgtata cagcattctg ggtgtggtga aacgaacttg ctggcccact
2281 gacctagaag aggccaaagc tgggggattt gtggtgggtt atacatccag tggaaatcca
2341 atcttccgta acccctgcac agagcagatt ctgaaacttc ttgacaattt gcttgcgctt
2401 ataagaaccc acaatacatt atatgcacca gaaatgctag ccaaaatggc agagcctttc
2461 accaaggctc tggatatgct tgacgcggaa aaatctgcta tattaggatt acctcaacct
2521 ctcttggaac tcaatgactc tcctgtcttc aaaaccgtct tggaaagaat gcagcgtttc
2581 ttctctaccc tctatgaaaa ctgttttcat atcctaggga aggcaggccc ttccatgcag
2641 caagacttct atactgtgga ggaccttgct acccagcttc tcagctcagc ctttgtcaac
2701 ttgaacaata ttcctgacta ccgactcaga cccatgcttc gtgtctttgt aaagcctctg
2761 gtgctcttct gtcccccaga gcactatgaa gccctggtat cccccatcct cggacctctt
2821 ttcacctacc tccatatgag gctttctcag aaatggcaag ttatcaacca aaggagcctg
2881 ctgtgtggag aagatgaggc tgcagatgaa aacccagagt ctcaagagat gctggaggag
2941 caactggtga ggatgttaac ccgagaagtc atggacctaa tcacggtttg ctgtgtttca
3001 aagaagggtg ctgaccacag tagtgctccc ccagcagatg gagacgatga agaaatgatg
3061 gccacagagg tcaccccctc agctatggca gagcttacag acctgggcaa atgtctgatg
3121 aagcatgagg atgtttgtac agcgctatta attacagcct tcaattccct ggcctggaaa
3181 gatactctgt cctgccagag gacaacctca cagctctgct ggcctctcct caaacaagtg
3241 ctgtcaggga cactgctcgc agatgcagtt acgtggcttt tcaccagtgt gctgaaaggc
3301 ttacagatgc acgggcagca cgacgggtgc atggcttccc tggtccatct ggccttccag
3361 atatatgagg cactgcgccc caggtacctg gagataagag ctgtaatgga gcaaatccct
3421 gaaatacaga aggactcact ggaccagttt gactgcaagc ttttaaaccc ctccctgcag
3481 aaagtggctg acaagcgccg aaaggaccaa ttcaaacgcc tcattgctgg ttgcattggg
3541 aaacccttgg gagagcagtt ccgaaaagaa gttcacatta agaatcttcc ctcacttttc
3601 aaaaaaacaa agccaatgct ggagacggag gtgctggaca atgatggggg tggcctggcc
3661 accatctttg aaccctgaat caagcttttg ggcatccttc ctcggccttt cttgtcatct
3721 cttctttccc tttgtagccg atctctaggc ccttcttgca ctgccacctc actttccacc
3781 actgtcagcc tggaaagaga tccaggtctg gagctggaga gaacaggccc tgtgcaggac
3841 cagaagtaat tatactaaag tatcaagaaa gggagttagg gcttaaacta ttctgtctag
3901 atgtcccaga tagttcccat tctacttgga gatttggctt ttccaagaaa agctagagca
3961 gagcagccct tctcccacaa gccctcccac ccccgtgcag ccacatacct gtacagaatg
4021 gtaactaagg gtgctgtgcc caaccctgcg actagcaagg ctcgcagcaa gagcacagcc
4081 ctcaactact tgtgccagag tttctcttgg accactccaa ctcccactga gcccttttgc
4141 tgctgggctg gcaggaaact ttccccactc cctaaggggc atgtctgggt taggtgctaa
4201 gtgctgaaga gaacttggtc agttctctca actttgcttt gggcaagaat ctggtcacct
4261 gatgggatcc atggtacagg ctactgctaa acttggcaca gtatcaagta tagtacctcc
4321 aaggaccagg gctgggaagt ctttagtgct aacatcccct ttagagttca cacatcttgc
4381 ccttccatga atgacccctc agtctggcct ccccagcctc aaggtccact caggcacaag
4441 agccacagta ccctagatag tgtcacatga caccgttgtc atccaaggat aatacagacc
4501 aactaggcta catctgtgat gagcagctag caaagccgct ggtcttctcc taggactaag
4561 tccaggtgcc ttccacaatc tcatggtctt tcaggtccct ggttactttt ctcaaaggcc
4621 atttccaaaa gaatacatgc cttcacatca caacctgtac tgtgagtcca ttctagaggt
4681 cactgaaagg ccctgtaaag agaggacatg gatacgggac ctggccctga ggttattact
4741 ggccgtaagg cagagttaat ccatacagaa accagtgtgt ccatgtgctc tgcacaaaaa
4801 cagacctgtt gtccatccag tccactgaca agagggtttc cccgagagcc gaagtggact
4861 gaagctacag tttttagctg gtgcgggcca caggcagggt cagattgaga agaagcaaag
4921 ctggggaagc agaagttggg agtcttgtgt tgctccctct tcctgtgtgg tgctctgggt
4981 ttctgtggat cgtgaaggcg atctcaagag tgtttccctc caaacctgat agctgcctat
5041 tcctgtctgg ttggggctgt ggaggatgta gttgtattta ttgcattgta atatttttaa
5101 catcctgtga cttcatgcta gaaattttct attgtttata gaaacttttt gtagaaacat
5161 taactctaaa gcacatctgc atgtcagtaa aaatctcagt ttcgtacaga aaaaaaaaaa
5221 aaaaaaaaaa a
//