LOCUS AF298591 2200 bp mRNA linear HUM 20-MAY-2001
DEFINITION Homo sapiens nonselective sodium potassium/proton exchanger (NHE7)
mRNA, complete cds.
ACCESSION AF298591
VERSION AF298591.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2200)
AUTHORS Numata,M. and Orlowski,J.
TITLE Molecular cloning and characterization of a novel (Na+,K+)/H+
exchanger localized to the trans-Golgi network
JOURNAL J. Biol. Chem. 276 (20), 17387-17394 (2001)
PUBMED 11279194
REFERENCE 2 (bases 1 to 2200)
AUTHORS Numata,M. and Orlowski,J.
TITLE Direct Submission
JOURNAL Submitted (23-AUG-2000) Physiology, McGill University, 3655
Promenade Sir-William-Osler, Montreal, QC H3G 1Y6, Canada
FEATURES Location/Qualifiers
source 1..2200
/db_xref="H-InvDB:HIT000076623"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp11.1-p11.4"
gene 1..2200
/gene="NHE7"
CDS 9..2186
/gene="NHE7"
/note="ion transporter; (Na+,K+)/H+ exchanger; similar to
Homo sapiens sequences presented in GenBank Accession
Numbers AA279477, AA648924, AL022165 and AL050307"
/codon_start=1
/product="nonselective sodium potassium/proton exchanger"
/protein_id="AAK54508.1"
/translation="MEPGDAARPGSGRATGAPPPRLLLLPLLLGWGLRVAAAASASSS
GAAAEDSSAMEELATEKEAEESHRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHET
GLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRAFSTLLVNVSGKFFEYTLKGEIS
PGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLG
TAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHA
DVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGS
FTMGAVTGVNANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGIT
QAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFV
AIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFALAIRDTASYARQM
MFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHWQYFRVGVDPDQD
PPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTL
PAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANGSSSSHTAS
TSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDNA"
BASE COUNT 490 a 595 c 570 g 545 t
ORIGIN
1 ccgggaccat ggagcctggt gacgcggcgc gccctggctc gggtcgggct accggggcgc
61 cgccgccgcg gctgctgctg ctgccgctgc tgctgggttg ggggctgcga gtcgcggccg
121 cggcctcggc ctcctcctct ggggcggcgg cggaggacag cagcgccatg gaggagctcg
181 ctactgagaa ggaggcggag gagagccacc ggcaagacag cgtgagcctg ctcaccttca
241 tcctgctgct cacgctcacc atcctcacca tctggctctt caagcaccgc cgggtgcgct
301 ttctgcacga gaccgggctg gccatgatct atgggctcat cgttggggtg atcctgaggt
361 atggtacccc tgctaccagt ggccgtgaca aatcactcag ctgcactcag gaagacaggg
421 ccttcagtac cttattagtg aatgtcagcg gaaagttctt cgaatacact ctgaaaggag
481 aaatcagtcc tggcaagatc aacagcgtag agcagaatga tatgctacgg aaggtaacat
541 tcgatccaga agtatttttc aacattcttc tgcctccaat tatttttcat gctggataca
601 gcttaaagaa gagacacttt ttcagaaatc ttggatctat actggcctat gccttcttgg
661 ggactgctgt ttcatgcttc attattggaa atctcatgta tggtgtggtg aagctcatga
721 agattatggg acagctctca gataaatttt actacacaga ttgtctcttt tttggagcaa
781 tcatctctgc cactgaccca gtgactgtgc tggcgatatt taatgaattg catgcagacg
841 tggatcttta cgcacttctt tttggagaga gcgtcctaaa tgatgctgtt gccattgtac
901 tgtcctcgtc tattgttgcc taccagccag cgggactgaa cactcacgcc tttgatgctg
961 ctgccttttt taagtcagtt ggcatttttc taggtatatt tagtggctct tttaccatgg
1021 gagctgtgac tggtgttaat gccaacgtga ctaagtttac caaactgcac tgcttccccc
1081 tgctggagac ggcgctgttc ttcctcatgt cctggagcac gtttctcttg gcagaagcct
1141 gcggatttac aggtgttgta gctgtccttt tctgtggaat cacacaagct cattacacct
1201 acaacaatct gtcggtggaa tcaagaagtc gaaccaagca gctctttgag gtgttacatt
1261 tcctggcaga gaacttcatc ttctcctaca tgggcctggc actgtttacc ttccagaagc
1321 acgttttcag ccccattttc atcatcggag cttttgttgc catcttcctg ggcagagccg
1381 cgcacatcta cccgctctcc ttcttcctca acttgggcag aaggcataag attggctgga
1441 attttcaaca catgatgatg ttttcaggcc tcaggggagc aatggcattt gcgttggcca
1501 tccgtgacac ggcatcctat gctcgccaga tgatgttcac gaccaccctt ctcattgtgt
1561 tcttcactgt ctggatcatt ggaggaggca cgacacccat gttgtcatgg cttaacatca
1621 gagttggcgt cgaggagccc tccgaagagg accagaatga acaccactgg cagtacttca
1681 gagttggtgt tgaccccgat caagacccac cacccaacaa cgacagcttt caagtcttac
1741 aaggggacgg cccagattct gccagaggaa accggacaaa acaggagagc gcatggatat
1801 tcaggctgtg gtacagcttt gatcacaatt acctgaagcc catcctcaca cacagtggtc
1861 ccccactaac caccacgctc cccgcctggt gtggcttact agctcgatgt ctgaccagtc
1921 cccaggtgta cgataaccaa gagccactga gagaggaaga ctctgatttc atcctgaccg
1981 aaggcgacct gacattgacc tacggggaca gcacagtgac tgcaaatggc tcctcaagtt
2041 cgcacaccgc ctccacgagt ctggagggca gccggagaac gaagagcagc tcggaggaag
2101 tgctggagcg agacctggga atgggagacc agaaggtttc gagccggggc acccgcctag
2161 tgtttcccct ggaagataat gcttgacttt ccccccaagc
//