LOCUS AF297866 4756 bp mRNA linear HUM 21-OCT-2000
DEFINITION Homo sapiens Hu-Claspin mRNA, complete cds.
ACCESSION AF297866
VERSION AF297866.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4756)
AUTHORS Kumagai,A. and Dunphy,W.G.
TITLE Claspin, a novel protein required for the activation of Chk1 during
a DNA replication checkpoint response in Xenopus egg extracts
JOURNAL Mol. Cell 6 (4), 839-849 (2000)
PUBMED 11090622
REFERENCE 2 (bases 1 to 4756)
AUTHORS Kumagai,A. and Dunphy,W.G.
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2000) Biology, California Institute of
Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA
FEATURES Location/Qualifiers
source 1..4756
/db_xref="H-InvDB:HIT000076614"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p34.1-p34.3"
CDS 81..4079
/codon_start=1
/product="Hu-Claspin"
/protein_id="AAG24515.1"
/translation="MTGEVGSEVHLEINDPNVISQEEADSPSDSGQGSYETIGPLSEG
DSDEEIFVSKKLKNRKVLQDSDSETEDTNASPEKTTYDSAEEENKENLYAGKNTKIKR
IYKTVADSDESYMEKSLYQENLEAQVKPCLELSLQSGNSTDFTTDRKSSKKHIHDKEG
TAGKAKVKSKRRLEKEERKMEKIRQLKKKETKNQEDDVEQPFNDSGCLLVDKDLFETG
LEDENNSPLEDEESLESIRAAVKNKVKKHKKKEPSLESGVHSFEEGSELSKGTTRKER
KAARLSKEALKQLHSETQRLIRESALNLPYHMPENKTIHDFFKRKPRPTCHGNAMALL
KSSKYQSSHHKEIIDTANTTEMNSDHHSKGSEQTTGAENEVETNALPVVSKETQIITG
SDESCRKDLVKNEELEIQEKQKQSDIRPSPGDSSVLQQESNFLGNNHSEECQVGGLVA
FEPHALEGEGPQNPEETDEKVEEPEQQNKSSAVGPPEKVRRFTLDRLKQLGVDVSIKP
RLGADEDSFVILEPETNRELEALKQRFWKHANPAAKPRAGQTVNVNVIVKDMGTDGKE
ELKADVVPVTLAPKKLDGASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDN
EDGSEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEGKEEEEEEEGNQETAEFLL
SSEEIETKDEKEMDKENNDGSSEIGKAVGFLSVPKSLSSDSTLLLFKDSSSKMGYSPT
EEKSETDENSGKQPSKLDEDDSCSLLTKESSHNSSFELIGSTIPSYQPCNRQTGRGTS
FFPTAGGFRSPSPGLFRASLVSSASKSSGKLSEPSLPIEDSQDLYNASPEPKTLFLGA
GDFQFCLEDDTQSQLLDADGFLNVRNHRNQYQALKPRLPLASMDENAMDANMDELLDL
CTGKFTSQAEKHLPRKSDKKENMEELLNLCSGKFTSQDASTPASSELNKQEKESSMGD
PMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHE
DDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVIDEVL
PSDEELQSQIKKIHMKTMLDDDKRQLRLYQERYLADGDLHSDGPGRMRKFRWKNIDDA
SQMDLFHRDSDDDQTEEQLDESEARWRKERIEREQWLRDMAQQGKITAEEEEEIGEDS
QFMILAKKVTAKALQKNASRPMVIQESKSLLRNPFEAIRPGSAQQVKTGSLLNQPKAV
LQKLAALSDHNPSAPRNSRNFVFHTLSPVKAEAAKESSKSQKIPEKDSDWLTWSGAPI
PGFFRLSFDPHG"
BASE COUNT 1626 a 896 c 1227 g 1007 t
ORIGIN
1 gacggcggga gccgctgctc tccggctgag ggaatcagag acagctccgt ccctagtgga
61 gcgcagggga ggcagaagtc atgacaggcg aggtgggttc tgaggttcac ctagaaatca
121 atgacccaaa cgtcatttca caagaggaag cagatagtcc ttcagatagt ggacagggca
181 gctatgaaac aattggaccc ttgagtgaag gagattcaga tgaagagata tttgtaagta
241 agaagttgaa aaacaggaag gttctacaag acagtgattc cgaaacagag gacacaaatg
301 cctctccaga gaaaactacc tatgacagtg ccgaggagga aaataaagag aatttatatg
361 ctgggaaaaa tacaaaaatc aaaaggattt acaaaactgt ggcagacagt gatgaaagtt
421 acatggaaaa gtctttgtat caggaaaatc ttgaagcgca agtgaaacct tgcttagagc
481 tgagtcttca gtctggaaac tctacagact ttaccactga cagaaagagt tccaaaaagc
541 acatacatga taaagaagga actgcaggaa aagcaaaagt aaaatcaaaa agaagacttg
601 agaaagagga gagaaaaatg gaaaaaatta gacagctaaa aaagaaggaa acaaaaaacc
661 aggaagatga tgtagaacag ccatttaatg acagtggctg tcttcttgtg gataaagacc
721 tttttgaaac tgggttggag gatgaaaata actctccatt ggaagatgaa gagtcattag
781 aatcaataag agcagctgta aaaaacaaag taaaaaagca caagaaaaaa gaaccatctt
841 tggagagtgg ggtccattca tttgaggaag gaagtgagtt atcaaaagga accacgagga
901 aggaaagaaa ggcagccaga ttaagtaaag aagcattaaa acaactgcat agtgagactc
961 agcgccttat tcgagagtct gcactgaacc ttccatatca tatgcctgag aataaaacca
1021 ttcatgattt cttcaaacgt aaaccccggc ccacttgcca cggaaatgcc atggcactat
1081 tgaagtcatc taaatatcag tcaagccatc acaaagaaat catagacact gcaaatacta
1141 ctgaaatgaa cagtgatcac catagtaaag gttctgagca gacaacaggt gcagaaaatg
1201 aagtggaaac taatgcactc cctgtagttt caaaggaaac ccagatcatt actggatcag
1261 atgagtcttg caggaaggat ttggtaaaaa atgaagagct agaaattcag gagaaacaga
1321 agcagagtga cattagacct tcacctgggg acagctcagt gttgcaacag gaatccaact
1381 tcctcgggaa caatcacagt gaggaatgtc aggttggagg gcttgtagca tttgaacctc
1441 atgccctgga gggtgaaggc ccccaaaatc cagaagaaac agatgagaaa gtggaagagc
1501 ctgagcagca aaataaatca tcagcagttg ggccacctga aaaagtgaga cggtttactc
1561 tggatagact taagcaactg ggagtagatg tttccattaa accacggcta ggtgctgatg
1621 aagattcctt tgtgatactt gaacctgaaa ccaacagaga actggaagcc ttgaagcagc
1681 gtttctggaa gcatgctaat ccagcagcca aacccagggc tggtcagaca gtgaatgtga
1741 acgtcatagt gaaagacatg ggcactgatg gaaaggaaga gctaaaagca gatgtggtac
1801 ctgtgacttt agcacctaag aagttggatg gagcaagcca cacaaaacca ggtgaaaagc
1861 ttcaggtgtt aaaagctaaa ctgcaagaag caatgaaact ccgaaggttt gaggagcgcc
1921 agaagcgcca agcactgttt aaattagata atgaagatgg gtctgaggaa gaggaggagg
1981 aagaggaaga aatgacagat gagtctgagg aagatggaga agagaaggta gagaaagaag
2041 agaaagagga agaactagag gaagaggagg ggaaagaaga ggaggaggaa gaagaaggaa
2101 atcaggagac tgcagaattc cttcttagta gtgaagaaat agaaacaaaa gatgaaaaag
2161 aaatggataa agaaaataat gatggcagta gtgaaattgg caaggcagtt ggcttcctct
2221 ctgttcccaa gtctctctca tcagattcta ctttacttct gtttaaggac agctcttcca
2281 agatgggtta ctctcctact gaagaaaaat cagaaacaga tgaaaactca ggcaagcagc
2341 ctagcaaact ggatgaggat gattcatgtt cattgctaac aaaggagagc agccacaata
2401 gcagctttga gctgattggc tccacgattc catcctatca gccttgcaac agacaaacag
2461 gccgtgggac cagttttttc cctacagcag gaggattcag atctccttcc cctgggctat
2521 ttcgagccag tttggtcagc tcagcttcta agagttcagg gaaactgtct gagccttcac
2581 ttcccataga ggattcccag gatctgtata acgcctcccc agagcctaag acacttttcc
2641 taggagcagg agacttccag ttctgtttag aagatgacac tcagagccaa ctgttggatg
2701 cagatgggtt cttaaatgtt agaaaccaca ggaatcagta ccaagctttg aagcctcgat
2761 tgccattggc cagtatggat gagaatgcca tggatgccaa catggatgag ctgttggatt
2821 tgtgtactgg aaagttcaca tctcaggctg aaaaacatct acccaggaag agtgacaaga
2881 aagagaacat ggaggaactt ctgaaccttt gttcaggaaa attcacttct caggatgcct
2941 ccactccagc ctcatcagag ttaaataaac aggagaagga gagcagcatg ggtgatccaa
3001 tggaagaagc acttgctctt tgctcaggct cttttcccac agacaaggaa gaggaagacg
3061 aggaggagga atttggagac tttcggcttg tttcaaatga taatgagttt gatagtgatg
3121 aggatgaaca cagtgactct ggtaatgatc tggcactgga agaccatgaa gatgatgatg
3181 aagaagaact cctgaagcga tctgagaagt tgaaaaggca aatgaggttg aggaaatacc
3241 tggaggatga ggcagaggtg tcaggaagtg atgtgggaag cgaagatgag tatgatgggg
3301 aagaaattga tgaatatgaa gaggacgtaa ttgatgaagt acttccttct gatgaggaac
3361 tgcagagtca aatcaagaaa atacacatga aaactatgtt ggatgatgat aagcgacagc
3421 tacgtttata ccaagagagg taccttgctg atggggatct gcacagcgat ggtcctgggc
3481 gaatgaggaa gtttcgatgg aaaaacatag atgatgcttc ccagatggac ttgttccaca
3541 gagactctga tgatgatcag actgaagaac agcttgatga gtcagaagcc aggtggagga
3601 aggagcgaat tgaacgagag cagtggcttc gggacatggc acagcagggg aaaattacag
3661 ctgaagaaga agaagaaatt ggggaggaca gtcagtttat gatactggcc aagaaagtta
3721 cagccaaagc actgcagaag aatgccagtc gccctatggt tattcaggaa tcaaagtctt
3781 tgctcagaaa tccttttgaa gccatcagac caggaagtgc tcaacaggtg aagacaggct
3841 cactgctaaa ccagcccaaa gctgtgcttc agaaactggc tgctctctct gaccataacc
3901 ccagtgctcc tcgaaattca agaaactttg tctttcatac actttctcct gtcaaggctg
3961 aggcggcaaa ggaatcgtct aagtctcaga agatcccaga gaaggactct gactggctca
4021 cctggagtgg agctcctatc cctggattct tcaggctttc atttgaccca catggttaag
4081 ctgggagaga cagagtccaa agagaggcgg agaagggcta ttctgggcag aacaaacaat
4141 tgatgacttt atggctctgt ggtctgggca gaactgcata accctagatc accaaagctg
4201 agagccttta ggagtgagga tttgggccgg gcatggtggc tcacgcctgt aatcccagca
4261 ctttgggagg ccgaggtggg tggatcacaa ggtcaggaga tcaagaccaa cctgaccaac
4321 atggtgaggc cccatctcta ctaaaaatac aaaaattagc tgacgtgatg catgcacctg
4381 taatcccagc tactcgggag gctgaggcgg gagaatcgct tgaacccggg aggttggagg
4441 ttgcggtggg ccgagattgc gccactgcac tccagcctgg gcgacagagc gggactccat
4501 ctcaaaaaaa aaaaaaaaaa agtgaggatt tgggtcaccc caggctgaag gccaggggaa
4561 cctgaatgat aagggaaggg aaaacttagg ccacagtctg attagaaatg gggctgaatt
4621 ccaccctgtt tttcctttac tggagattca atttgaatta ctctgcctcc cttcttattc
4681 cttttccctt ttaaaatagt catcataatc ataaaaattt cttttccaaa aaaaaaaaaa
4741 aaaaaaaaaa aaaaaa
//