LOCUS AF296673 3002 bp mRNA linear HUM 27-MAR-2001
DEFINITION Homo sapiens toll-like receptor 10 mRNA, complete cds.
ACCESSION AF296673
VERSION AF296673.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3002)
AUTHORS Chuang,T. and Ulevitch,R.J.
TITLE Identification of hTLR10: a novel human Toll-like receptor
preferentially expressed in immune cells
JOURNAL Biochim. Biophys. Acta 1518 (1-2), 157-161 (2001)
PUBMED 11267672
REFERENCE 2 (bases 1 to 3002)
AUTHORS Chuang,T.H. and Ulevitch,R.J.
TITLE Direct Submission
JOURNAL Submitted (16-AUG-2000) Immunology, The Scripps Research Institute,
10550 North Torrey Pines Road, La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..3002
/db_xref="H-InvDB:HIT000076593"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="spleen"
CDS 487..2922
/note="TLR10"
/codon_start=1
/product="toll-like receptor 10"
/protein_id="AAK26744.1"
/translation="MRLIRNIYIFCSIVMTAEGDAPELPEERELMTNCSNMSLRKVPA
DLTPATTTLDLSYNLLFQLQSSDFHSVSKLRVLILCHNRIQQLDLKTFEFNKELRYLD
LSNNRLKSVTWYLLAGLRYLDLSFNDFDTMPICEEAGNMSHLEILGLSGAKIQKSDFQ
KIAHLHLNTVFLGFRTLPHYEEGSLPILNTTKLHIVLPMDTNFWVLLRDGIKTSKILE
MTNIDGKSQFVSYEMQRNLSLENAKTSVLLLNKVDLLWDDLFLILQFVWHTSVEHFQI
RNVTFGGKAYLDHNSFDYSNTVMRTIKLEHVHFRVFYIQQDKIYLLLTKMDIENLTIS
NAQMPHMLFPNYPTKFQYLNFANNILTDELFKRTIQLPHLKTLILNGNKLETLSLVSC
FANNTPLEHLDLSQNLLQHKNDENCSWPETVVNMNLSYNKLSDSVFRCLPKSIQILDL
NNNQIQTVPKETIHLMALRELNIAFNFLTDLPGCSHFSRLSVLNIEMNFILSPSLDFV
QSCQEVKTLNAGRNPFRCTCELKNFIQLETYSEVMMVGWSDSYTCEYPLNLRGIRLKD
VHLHELSCNTALLIVTIVVIMLVLGLAVAFCCLHFDLPWYLRMLGQCTQTWHRVRKTT
QEQLKRNVRFHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENI
VSFIEKSYKSIFVLSPNFVQNEWCHYEFYFAHHNLFHENSDHIILILLEPIPFYCIPT
RYHKLKALLEKKAYLEWPKDRRKCGLFWANLRAAINVNVLATREMYELQTFTELNEES
RGSTISLMRTDCL"
BASE COUNT 942 a 599 c 552 g 909 t
ORIGIN
1 gtggcttggt attcactggc aggtttcaga catttagatc tttcttttaa tgactaacac
61 catgcctatc tgtggagaag ctggcaacat gtcacacctg gaaattgttt ttcaacatta
121 atactattat ttggcagtaa tccagattgc ttttgccacc aacctgaaga catatagagg
181 cagaaggaca ggaataattc tatttgtttc ctgttttgaa acttccatct gtaaggctat
241 caaaaggaga tgtgagagag ggtattgagt ctggcctgac aatgcagttc ttaaaccaaa
301 ggtccattat gcttctcctc tctgagaatc ctgacttacc tcaacaacgg agacatggca
361 cagtagccag cttggagact tctcagccaa tgctctgaga tcaagtcgaa gacccaatat
421 acagggtttt gagctcatct tcatcattca tatgaggaaa taagtggtaa aatccttgga
481 aatacaatga gactcatcag aaacatttac atattttgta gtattgttat gacagcagag
541 ggtgatgctc cagagctgcc agaagaaagg gaactgatga ccaactgctc caacatgtct
601 ctaagaaagg ttcccgcaga cttgacccca gccacaacga cactggattt atcctataac
661 ctcctttttc aactccagag ttcagatttt cattctgtct ccaaactgag agttttgatt
721 ctatgccata acagaattca acagctggat ctcaaaacct ttgaattcaa caaggagtta
781 agatatttag atttgtctaa taacagactg aagagtgtaa cttggtattt actggcaggt
841 ctcaggtatt tagatctttc ttttaatgac tttgacacca tgcctatctg tgaggaagct
901 ggcaacatgt cacacctgga aatcctaggt ttgagtgggg caaaaataca aaaatcagat
961 ttccagaaaa ttgctcatct gcatctaaat actgtcttct taggattcag aactcttcct
1021 cattatgaag aaggtagcct gcccatctta aacacaacaa aactgcacat tgttttacca
1081 atggacacaa atttctgggt tcttttgcgt gatggaatca agacttcaaa aatattagaa
1141 atgacaaata tagatggcaa aagccaattt gtaagttatg aaatgcaacg aaatcttagt
1201 ttagaaaatg ctaagacatc ggttctattg cttaataaag ttgatttact ctgggacgac
1261 cttttcctta tcttacaatt tgtttggcat acatcagtgg aacactttca gatccgaaat
1321 gtgacttttg gtggtaaggc ttatcttgac cacaattcat ttgactactc aaatactgta
1381 atgagaacta taaaattgga gcatgtacat ttcagagtgt tttacattca acaggataaa
1441 atctatttgc ttttgaccaa aatggacata gaaaacctga caatatcaaa tgcacaaatg
1501 ccacacatgc ttttcccgaa ttatcctacg aaattccaat atttaaattt tgccaataat
1561 atcttaacag acgagttgtt taaaagaact atccaactgc ctcacttgaa aactctcatt
1621 ttgaatggca ataaactgga gacactttct ttagtaagtt gctttgctaa caacacaccc
1681 ttggaacact tggatctgag tcaaaatcta ttacaacata aaaatgatga aaattgctca
1741 tggccagaaa ctgtggtcaa tatgaatctg tcatacaata aattgtctga ttctgtcttc
1801 aggtgcttgc ccaaaagtat tcaaatactt gacctaaata ataaccaaat ccaaactgta
1861 cctaaagaga ctattcatct gatggcctta cgagaactaa atattgcatt taattttcta
1921 actgatctcc ctggatgcag tcatttcagt agactttcag ttctgaacat tgaaatgaac
1981 ttcattctca gcccatctct ggattttgtt cagagctgcc aggaagttaa aactctaaat
2041 gcgggaagaa atccattccg gtgtacctgt gaattaaaaa atttcattca gcttgaaaca
2101 tattcagagg tcatgatggt tggatggtca gattcataca cctgtgaata ccctttaaac
2161 ctaaggggaa ttaggttaaa agacgttcat ctccacgaat tatcttgcaa cacagctctg
2221 ttgattgtca ccattgtggt tattatgcta gttctggggt tggctgtggc cttctgctgt
2281 ctccactttg atctgccctg gtatctcagg atgctaggtc aatgcacaca aacatggcac
2341 agggttagga aaacaaccca agaacaactc aagagaaatg tccgattcca cgcatttatt
2401 tcatacagtg aacatgattc tctgtgggtg aagaatgaat tgatccccaa tctagagaag
2461 gaagatggtt ctatcttgat ttgcctttat gaaagctact ttgaccctgg caaaagcatt
2521 agtgaaaata ttgtaagctt cattgagaaa agctataagt ccatctttgt tttgtctccc
2581 aactttgtcc agaatgagtg gtgccattat gaattttact ttgcccacca caatctcttc
2641 catgaaaatt ctgatcatat aattcttatc ttactggaac ccattccatt ctattgcatt
2701 cccaccaggt atcataaact gaaagctctc ctggaaaaaa aagcatactt ggaatggccc
2761 aaggataggc gtaaatgtgg gcttttctgg gcaaaccttc gagctgctat taatgttaat
2821 gtattagcca ccagagaaat gtatgaactg cagacattca cagagttaaa tgaagagtct
2881 cgaggttcta caatctctct gatgagaaca gattgtctat aaaatcccac agtccttggg
2941 aagttgggga ccacatacac tgttgggatg tacattgata caacctttat gatggcaatt
3001 tg
//