LOCUS AF293384 1770 bp mRNA linear HUM 15-SEP-2000
DEFINITION Homo sapiens PLIC-1 mRNA, complete cds.
ACCESSION AF293384
VERSION AF293384.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1770)
AUTHORS Kleijnen,M.F., Shih,A.H., Zhou,P., Kumar,S., Soccio,R.E.,
Kedersha,N.L., Gill,G. and Howley,P.M.
TITLE The hPLIC proteins may provide a link between the ubiquitination
machinery and the proteasome
JOURNAL Mol. Cell 6 (2), 409-419 (2000)
PUBMED 10983987
REFERENCE 2 (bases 1 to 1770)
AUTHORS Kleijnen,M.F., Shih,A.H., Zhou,P., Kumar,S., Soccio,R.E.,
Kedersha,N.L., Gill,G. and Howley,P.M.
TITLE Direct Submission
JOURNAL Submitted (04-AUG-2000) Pathology, Harvard Medical School, 200
Longwood Avenue, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..1770
/db_xref="H-InvDB:HIT000076549"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="B cell"
CDS 1..1770
/function="role in ubiquitin-dependent proteasomal
degradation"
/note="ubiquitin-like type II"
/codon_start=1
/product="PLIC-1"
/protein_id="AAG02473.1"
/translation="MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTP
KEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTV
HLVIKTQNRPQDHSAQQTNTAGSNVTTSSTPNSNSTSGSATSNPFGLGGLGGLAGLSS
LGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQL
IQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMY
TDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWAPQTSQSSSA
SSGTASTVGGTTGSTASGTSGQSTTAPNLVPGVGASMFNTPGMQSLLQQITENPQLMQ
NMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDT
LSAMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNATPS
ENTSPTAGTTEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANL
QALIATGGDINAAIERLLGSQPS"
BASE COUNT 529 a 431 c 406 g 404 t
ORIGIN
1 atggccgaga gtggtgaaag cggcggtcct ccgggctccc aggatagcgc cgccggagcc
61 gaaggtgctg gcgcccccgc ggccgctgcc tccgcggagc ccaaaatcat gaaagtcacc
121 gtgaagaccc cgaaggaaaa ggaggaattc gccgtgcccg agaatagctc cgtccagcag
181 tttaaggaag aaatctctaa acgttttaaa tcacatactg accaacttgt gttgatattt
241 gctggaaaaa ttttgaaaga tcaagatacc ttgagtcagc atggaattca tgatggactt
301 actgttcacc ttgtcattaa aacacaaaac aggcctcagg atcattcagc tcagcaaaca
361 aatacagctg gaagcaatgt tactacatca tcaactccta atagtaactc tacatctggt
421 tctgctacta gcaacccttt tggtttaggt ggccttgggg gacttgcagg tctgagtagc
481 ttgggtttga atactaccaa cttctctgaa ctacagagtc agatgcagcg acaacttttg
541 tctaaccctg aaatgatggt ccagatcatg gaaaatccct ttgttcagag catgctctca
601 aatcctgacc tgatgagaca gttaattatg gccaatccac aaatgcagca gttgatacag
661 agaaatccag aaattagtca tatgttgaat aatccagata taatgagaca aacgttggaa
721 cttgccagga atccagcaat gatgcaggag atgatgagga accaggaccg agctttgagc
781 aacctagaaa gcatcccagg gggatataat gctttaaggc gcatgtacac agatattcag
841 gaaccaatgc tgagtgctgc acaagagcag tttggtggta atccatttgc ttccttggtg
901 agcaatacat cctctggtga aggtagtcaa ccttcccgta cagaaaatag agatccacta
961 cccaatccat gggctccaca gacttcccag agttcatcag cttccagcgg cactgccagc
1021 actgtgggtg gcactactgg tagtactgcc agtggcactt ctgggcagag tactactgcg
1081 ccaaatttgg tgcctggagt aggagctagt atgttcaaca caccaggaat gcagagcttg
1141 ttgcaacaaa taactgaaaa cccacaactt atgcaaaaca tgttgtctgc cccctacatg
1201 agaagcatga tgcagtcact aagccagaat cctgaccttg ctgcacagat gatgctgaat
1261 aatcccctat ttgctggaaa tcctcagctt caagaacaaa tgagacaaca gctcccaact
1321 ttcctccaac aaatgcagaa tcctgataca ctatcagcaa tgtcaaaccc tagagcaatg
1381 caggccttgt tacagattca gcagggttta cagacattag caacggaagc cccgggcctc
1441 atcccagggt ttactcctgg cttgggggca ttaggaagca ctggaggctc ttcgggaact
1501 aatggatcta acgccacacc tagtgaaaac acaagtccca cagcaggaac cactgaacct
1561 ggacatcagc agtttattca gcagatgctg caggctcttg ctggagtaaa tcctcagcta
1621 cagaatccag aagtcagatt tcagcaacaa ctggaacaac tcagtgcaat gggatttttg
1681 aaccgtgaag caaacttgca agctctaata gcaacaggag gtgatatcaa tgcagctatt
1741 gaaaggttac tgggctccca gccatcatag
//