LOCUS AF293340 2607 bp mRNA linear HUM 18-APR-2002
DEFINITION Homo sapiens collagen-like Alzheimer amyloid plaque component
precursor type I mRNA, complete cds.
ACCESSION AF293340
VERSION AF293340.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2607)
AUTHORS Hashimoto,T., Wakabayashi,T., Watanabe,A., Kowa,H., Hosoda,R.,
Nakamura,A., Kanazawa,I., Arai,T., Takio,K., Mann,D.M.A. and
Iwatsubo,T.
TITLE CLAC: a novel Alzheimer amyloid plaque component derived from a
transmembrane precursor, CLAC-P/collagen type XXV
JOURNAL EMBO J. 21 (7), 1524-1534 (2002)
PUBMED 11927537
REFERENCE 2 (bases 1 to 2607)
AUTHORS Hashimoto,T., Wakabayashi,T. and Iwatsubo,T.
TITLE Direct Submission
JOURNAL Submitted (03-AUG-2000) Neuropathology and Neuroscience, Graduate
School of Pharmaceutical Sciences, University of Tokyo, 7-3-1
Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
FEATURES Location/Qualifiers
source 1..2607
/db_xref="H-InvDB:HIT000076541"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 532..2496
/note="CLAC-P type I"
/codon_start=1
/product="collagen-like Alzheimer amyloid plaque component
precursor type I"
/protein_id="AAK35008.1"
/translation="MLLKKHAGKGGGREPRSEDPTPAEQHCSRTMPPCAVLAALLSVV
AVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSY
EHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGD
QGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPR
GMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPG
PKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLP
GLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGT
RGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATKIIDYNGNLHEALQRITTLTVTGP
PGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGAN
GMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGP
KGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEK
GEPGQPGLDGLDAPCQLGPDGLPMPGCWQK"
BASE COUNT 658 a 648 c 837 g 464 t
ORIGIN
1 ccgcgacttc ggcttcgcga gtagcattgg ttccttgggt ttatttcgtt ttcctctctc
61 ttctccacct tagtcgcccc tttcgcgctg cgctgtagcg tgctctcaca gcctttttgc
121 cttgaactga atgcaggtgg gaaacaggtc ggcgtgccga aagacaccga gtaggtagaa
181 ataaggcaaa ctcacagagg cgcaacaggt ccggtcctcc gtggccaggg cgagccgcgg
241 ccccgcgtgg cgcctcggcc gttgccctcg gaccctgagc ggccactgtt ggggccctcg
301 aaagaggtgt cggtcctctg ggagtcggaa gagctgtctg ggtgggtttc gtcttgcttt
361 ttaccccacc gccacccagt ccccggacgg agggtgcttt tcacttccag ctgggaggag
421 agaagaaagc ggggatggtg cacgcctgcg ggtctggacg ctgagcaagg caggggatta
481 tttgaggtgt agagggtggg aagcgaagcc gagacggccg accccgccac gatgctgctg
541 aagaagcacg cagggaaagg agggggccgg gagcccagat ccgaggaccc gacccctgcc
601 gaacagcatt gttcccggac catgcccccg tgtgccgtcc tggcggccct cctgtcagtg
661 gtggccgtgg tgtcttgcct gtacctgggt gtgaaaacca acgacctcca ggcgaggatc
721 gccgctctcg aatccgccaa aggggccccc tccattcatc tgctgcctga taccctggat
781 cacctcaaga ctatggtgca agagaaagtg gagcgacttc tggctcagaa atcctatgaa
841 catatggcta aaataagaat cgcaagagaa gcaccttcag aatgtaactg cccagcaggc
901 cctccaggga aacgaggtaa gagaggccga agaggagaat ctggtcctcc tggacagcct
961 ggtcctcagg gccctcctgg tccaaaaggc gataagggag aacaaggtga tcagggacct
1021 aggatggtgt ttcctaaaat caatcatggg tttctctctg ctgatcagca gctcattaaa
1081 cgccgcctga ttaagggtga ccaaggacag gcagggcctc caggaccccc tggccctcca
1141 ggcccaagag ggccacctgg ggacacaggg aaagatggcc cccgtggaat gccaggagta
1201 cccggtgaac caggaaagcc aggagaacaa ggcttgatgg gtcctctagg gcctccggga
1261 caaaagggtt ctattggagc acctggaatt ccagggatga atgggcaaaa gggtgagccc
1321 gggttgcctg gagcagtagg acagaatgga ataccaggac ctaagggaga acctggagaa
1381 caaggtgaaa agggagacgc tggagagaac ggccccaagg gtgacacagg cgaaaagggt
1441 gaccctggat catctgctgc aggaattaag ggagaacctg gggaatctgg tcgtccaggg
1501 caaaagggtg aaccagggct tcctgggctt cctggacttc cggggataaa gggagaacca
1561 ggtttcattg gtcctcaagg agaaccaggc ttaccaggtt taccaggaac aaaaggtgaa
1621 cggggggaag cagggcctcc tggaagaggt gagcgagggg aacctggagc ccccggacca
1681 aaggggaaac aaggtgaatc aggaactaga ggcccaaagg ggtcaaaggg ggatcgtgga
1741 gaaaaagggg actctggagc tcagggacca aggggtccac ctggtcaaaa aggggatcaa
1801 ggagccacta agatcataga ctacaacggc aacctccacg aagccttaca gaggattacc
1861 accttaactg tcacgggtcc ccctggacct cctggacctc aaggactaca agggccaaag
1921 ggagagcagg gatctccagg aatcccagga atggatggag agcagggact caaaggctca
1981 aagggagaca tgggggaccc aggtatgaca ggtgaaaaag gaggaattgg acttcctgga
2041 ttaccgggag ccaatggaat gaaaggagaa aaaggagatt ctggaatgcc gggtccacag
2101 ggtccttcta tcataggccc accaggccca ccaggtcccc atggcccacc tggccccatg
2161 ggacctcatg gacttcctgg accaaagggt acagatggtc ctatgggacc ccatggccct
2221 gcaggtccca aaggagaaag aggtgaaaaa ggagctatgg gagagcctgg accaagaggg
2281 ccctatgggc tgcctgggaa agatggagag cctggtcttg atggcttccc tggtccacgg
2341 ggtgagaagg gtgatctagg agaaaaggga gaaaagggat tccgtggcgt taagggggaa
2401 aaaggggagc caggccagcc tggcctggat gggctggatg ccccttgcca attggggcca
2461 gatggcttac ccatgcctgg ctgttggcaa aagtgatgaa tctaaccttt caagcatgaa
2521 gttgtgtata taagggtcca tttttaatat ttatagttga aaactgaatt gcagatttta
2581 caagtctgag atatgtttac atagggc
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