LOCUS AF291820 3325 bp mRNA linear HUM 15-JUN-2001
DEFINITION Homo sapiens ACE-related carboxypeptidase ACE2 mRNA, complete cds.
ACCESSION AF291820
VERSION AF291820.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3325)
AUTHORS Donoghue,M., Hsieh,F., Baronas,E., Godbout,K., Gosselin,M.,
Stagliano,N., Donovan,M., Woolf,B., Robison,K., Jeyaseelan,R.,
Breitbart,R.E. and Acton,S.
TITLE A novel angiotensin-converting enzyme-related carboxypeptidase
(ACE2) converts angiotensin I to angiotensin 1-9
JOURNAL Circ. Res. 87 (5), E1-E9 (2000)
PUBMED 10969042
REFERENCE 2 (bases 1 to 3325)
AUTHORS Donoghue,M., Woolf,B., Robison,K. and Acton,S.
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2000) Cardiovascular Biology, Millennium
Pharmaceuticals, Inc, 75 Sidney Street, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..3325
/db_xref="H-InvDB:HIT000076479"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
CDS 21..2438
/codon_start=1
/product="ACE-related carboxypeptidase ACE2"
/protein_id="AAF99721.1"
/translation="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSS
LASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ
NGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE
RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYS
RGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWT
NLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLT
DPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLL
RNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTL
PFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSN
DYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPW
TLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISL
KSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFN
FFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVS
IWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNPGFQNT
DDVQTSF"
BASE COUNT 1022 a 637 c 747 g 919 t
ORIGIN
1 atcttggctc acaggggacg atgtcaagct cttcctggct ccttctcagc cttgttgctg
61 taactgctgc tcagtccacc attgaggaac aggccaagac atttttggac aagtttaacc
121 acgaagccga agacctgttc tatcaaagtt cacttgcttc ttggaattat aacaccaata
181 ttactgaaga gaatgtccaa aacatgaata atgctgggga caaatggtct gcctttttaa
241 aggaacagtc cacacttgcc caaatgtatc cactacaaga aattcagaat ctcacagtca
301 agcttcagct gcaggctctt cagcaaaatg ggtcttcagt gctctcagaa gacaagagca
361 aacggttgaa cacaattcta aatacaatga gcaccatcta cagtactgga aaagtttgta
421 acccagataa tccacaagaa tgcttattac ttgaaccagg tttgaatgaa ataatggcaa
481 acagtttaga ctacaatgag aggctctggg cttgggaaag ctggagatct gaggtcggca
541 agcagctgag gccattatat gaagagtatg tggtcttgaa aaatgagatg gcaagagcaa
601 atcattatga ggactatggg gattattgga gaggagacta tgaagtaaat ggggtagatg
661 gctatgacta cagccgcggc cagttgattg aagatgtgga acataccttt gaagagatta
721 aaccattata tgaacatctt catgcctatg tgagggcaaa gttgatgaat gcctatcctt
781 cctatatcag tccaattgga tgcctccctg ctcatttgct tggtgatatg tggggtagat
841 tttggacaaa tctgtactct ttgacagttc cctttggaca gaaaccaaac atagatgtta
901 ctgatgcaat ggtggaccag gcctgggatg cacagagaat attcaaggag gccgagaagt
961 tctttgtatc tgttggtctt cctaatatga ctcaaggatt ctgggaaaat tccatgctaa
1021 cggacccagg aaatgttcag aaagcagtct gccatcccac agcttgggac ctggggaagg
1081 gcgacttcag gatccttatg tgcacaaagg tgacaatgga cgacttcctg acagctcatc
1141 atgagatggg gcatatccag tatgatatgg catatgctgc acaacctttt ctgctaagaa
1201 atggagctaa tgaaggattc catgaagctg ttggggaaat catgtcactt tctgcagcca
1261 cacctaagca tttaaaatcc attggtcttc tgtcacccga ttttcaagaa gacaatgaaa
1321 cagaaataaa cttcctgctc aaacaagcac tcacgattgt tgggactctg ccatttactt
1381 acatgttaga gaagtggagg tggatggtct ttaaagggga aattcccaaa gaccagtgga
1441 tgaaaaagtg gtgggagatg aagcgagaga tagttggggt ggtggaacct gtgccccatg
1501 atgaaacata ctgtgacccc gcatctctgt tccatgtttc taatgattac tcattcattc
1561 gatattacac aaggaccctt taccaattcc agtttcaaga agcactttgt caagcagcta
1621 aacatgaagg ccctctgcac aaatgtgaca tctcaaactc tacagaagct ggacagaaac
1681 tgttcaatat gctgaggctt ggaaaatcag aaccctggac cctagcattg gaaaatgttg
1741 taggagcaaa gaacatgaat gtaaggccac tgctcaacta ctttgagccc ttatttacct
1801 ggctgaaaga ccagaacaag aattcttttg tgggatggag taccgactgg agtccatatg
1861 cagaccaaag catcaaagtg aggataagcc taaaatcagc tcttggagat aaagcatatg
1921 aatggaacga caatgaaatg tacctgttcc gatcatctgt tgcatatgct atgaggcagt
1981 actttttaaa agtaaaaaat cagatgattc tttttgggga ggaggatgtg cgagtggcta
2041 atttgaaacc aagaatctcc tttaatttct ttgtcactgc acctaaaaat gtgtctgata
2101 tcattcctag aactgaagtt gaaaaggcca tcaggatgtc ccggagccgt atcaatgatg
2161 ctttccgtct gaatgacaac agcctagagt ttctggggat acagccaaca cttggacctc
2221 ctaaccagcc ccctgtttcc atatggctga ttgtttttgg agttgtgatg ggagtgatag
2281 tggttggcat tgtcatcctg atcttcactg ggatcagaga tcggaagaag aaaaataaag
2341 caagaagtgg agaaaatcct tatgcctcca tcgatattag caaaggagaa aataatccag
2401 gattccaaaa cactgatgat gttcagacct ccttttagaa aaatctatgt ttttcctctt
2461 gaggtgattt tgttgtatgt aaatgttaat ttcatggtat agaaaatata agatgataaa
2521 gatatcatta aatgtcaaaa ctatgactct gttcagaaaa aaaattgtcc aaagacaaca
2581 tggccaagga gagagcatct tcattgacat tgctttcagt atttatttct gtctctggat
2641 ttgacttctg ttctgtttct taataaggat tttgtattag agtatattag ggaaagtgtg
2701 tatttggtct cacaggctgt tcagggataa tctaaatgta aatgtctgtt gaatttctga
2761 agttgaaaac aaggatatat cattggagca agtgttggat cttgtatgga atatggatgg
2821 atcacttgta aggacagtgc ctgggaactg gtgtagctgc aaggattgag aatggcatgc
2881 attagctcac tttcatttaa tccattgtca aggatgacat gctttcttca cagtaactca
2941 gttcaagtac tatggtgatt tgcctacagt gatgtttgga atcgatcatg ctttcttcaa
3001 ggtgacaggt ctaaagagag aagaatccag ggaacaggta gaggacattg ctttttcact
3061 tccaaggtgc ttgatcaaca tctccctgac aacacaaaac tagagccagg ggcctccgtg
3121 aactcccaga gcatgcctga tagaaactca tttctactgt tctctaactg tggagtgaat
3181 ggaaattcca actgtatgtt caccctctga agtgggtacc cagtctctta aatcttttgt
3241 atttgctcac agtgtttgag cagtgctgag cacaaagcag acactcaata aatgctagat
3301 ttacacactc aaaaaaaaaa aaaaa
//