LOCUS AF287894 1465 bp mRNA linear HUM 07-FEB-2001
DEFINITION Homo sapiens PIST (PIST) mRNA, complete cds.
ACCESSION AF287894
VERSION AF287894.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1465)
AUTHORS Neudauer,C.L., Joberty,G. and Macara,I.G.
TITLE PIST: a novel PDZ/coiled-coil domain binding partner for the
rho-family GTPase TC10
JOURNAL Biochem. Biophys. Res. Commun. 280 (2), 541-547 (2001)
PUBMED 11162552
REFERENCE 2 (bases 1 to 1465)
AUTHORS Neudauer,C.L., Joberty,G. and Macara,I.G.
TITLE Direct Submission
JOURNAL Submitted (14-JUL-2000) Markey Center for Cell Signaling,
University of Virginia, West complex, Charlottesville, VA 22908,
USA
FEATURES Location/Qualifiers
source 1..1465
/db_xref="H-InvDB:HIT000076330"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q21"
/tissue_type="brain"
gene 1..1465
/gene="PIST"
CDS 77..1465
/gene="PIST"
/note="PDZ domain-containing protein"
/codon_start=1
/product="PIST"
/protein_id="AAG00572.1"
/translation="MSAGGPCPAAAGGGPGGASCSVGAPGGVSMFRWLEVLEKEFDKA
FVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKAQSVSQINHKLEAQLVDLK
SELTETQAEKVVLEKEVHDQLLQLHSIQLQLHAKTGQSADSGTIKAKLSGPSVEELER
ELEANKKEKMKEAQLEAEVKLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRV
QQIQLLGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRPMQAPPGHDQDS
LKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGD
AILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYR
LYLDELEGGGNPGASCKDTSGEIKVLQGFNKKAVTDTHENGDLGTASETPLDDGASKL
DDLHTLYHKKSY"
misc_feature 323..499
/gene="PIST"
/note="Region: coiled-coil region"
misc_feature 524..703
/gene="PIST"
/note="Region: coiled-coil region"
misc_feature 596..664
/gene="PIST"
/note="Region: leucine zipper"
misc_feature 935..1186
/gene="PIST"
/note="Region: PDZ domain"
BASE COUNT 433 a 301 c 408 g 323 t
ORIGIN
1 tcagtcccag cagttccctt cgtgcgcggg gggcggcgag ggtcttcagc agtcgggaga
61 ggcccttgac ggcgccatgt cggcgggcgg tccatgccca gcagcagccg gagggggccc
121 agggggcgcc tcctgctccg tgggggcccc tggcggggta tccatgttcc ggtggctgga
181 ggtgctggag aaggagttcg acaaagcttt tgtggatgtg gatctgctcc tgggagagat
241 cgatccagac caagcggaca tcacttatga ggggcgacag aagatgacca gcctgagctc
301 ctgctttgca cagctttgcc acaaagccca gtctgtgtct caaatcaacc acaagctgga
361 ggcacagttg gtggatctga aatctgaact gacagaaacc caagcagaga aagttgtttt
421 ggagaaagaa gtacatgatc agcttttaca gctgcactct attcagctgc agcttcatgc
481 taaaactggt caaagtgctg actctggtac cattaaggca aaattgtctg gcccctctgt
541 ggaggagctg gaaagagagc ttgaggcaaa caaaaaagaa aaaatgaaag aagcacaact
601 tgaagctgaa gtgaaattgt tgagaaaaga gaatgaagcc cttcgtagac atatagctgt
661 tctccaggct gaagtatatg gggcgagact agctgccaag tacttggata aggaactggc
721 aggaagggtc caacagatac aattgctagg acgagatatg aagggacctg ctcatgataa
781 gctttggaac caattagaag ctgaaataca tttgcatcgt cacaaaactg tgatccgagc
841 ctgcagagga cgtaatgact tgaaacgacc aatgcaagca ccaccaggcc atgatcaaga
901 ttccctaaag aaaagccaag gtgttggtcc aattagaaaa gttctcctcc ttaaggaaga
961 tcatgaaggc cttggcattt caattacagg tgggaaagaa catggtgttc caatcctcat
1021 ctctgagatc catccggggc aacctgctga tagatgcgga gggctgcacg ttggggatgc
1081 tattttggca gtcaacggag ttaacctaag ggacacaaag cataaagaag ctgtaactat
1141 tctttctcag cagagaggag agattgaatt tgaagtagtt tatgtggctc ctgaagtgga
1201 ttctgatgat gaaaacgtag agtatgaaga tgagagtgga catcgttacc gtttgtacct
1261 tgatgagtta gaaggaggtg gtaaccctgg tgctagttgc aaagacacaa gtggggaaat
1321 caaagtatta caaggattta ataagaaggc agtaactgac acacatgaaa atggagacct
1381 gggcactgca agtgaaactc cgctagatga cggtgcttca aaattagatg atctgcacac
1441 tctgtatcat aaaaaatcgt attaa
//