LOCUS AF286160 1410 bp mRNA linear HUM 20-SEP-2000
DEFINITION Homo sapiens Tandem PH Domain Containing Protein-1 mRNA, complete
cds.
ACCESSION AF286160
VERSION AF286160.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1410)
AUTHORS Dowler,S., Currie,R.A., Campbell,D.G., Deak,M., Kular,G.,
Downes,C.P. and Alessi,D.R.
TITLE Identification of pleckstrin-homology-domain-containing proteins
with novel phosphoinositide-binding specificities
JOURNAL Biochem. J. 351 (Pt 1), 19-31 (2000)
PUBMED 11001876
REFERENCE 2 (bases 1 to 1410)
AUTHORS Dowler,S.J. and Campbell,D.G.
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2000) MRC Protein Phosphorylation Unit,
University of Dundee, Dow Street, Dundee DD1 5EH, Scotland
FEATURES Location/Qualifiers
source 1..1410
/db_xref="H-InvDB:HIT000076300"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 67..1281
/note="TAPP1; adaptor"
/codon_start=1
/product="Tandem PH Domain Containing Protein-1"
/protein_id="AAG15197.1"
/translation="MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMD
NPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVE
WVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEV
NECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDEN
TIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEE
MHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAAAATSHSTASRSNSLV
STFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLV
DLDDASLPVSDV"
misc_feature 88..402
/note="Region: pleckstrin homology domain"
misc_feature 640..933
/note="Region: pleckstrin homology domain"
misc_feature 1268..1278
/note="Region: putative PDZ binding site"
BASE COUNT 423 a 307 c 319 g 361 t
ORIGIN
1 tttggtgcag tttagcatgt tcctctgtgt tctgcatctc ctgtagtgta atgttcaagc
61 tcagaaatgc cttatgtgga tcgtcagaat cgcatttgtg gttttctaga cattgaagaa
121 aatgaaaaca gtgggaaatt tcttcgaagg tacttcatac tggataccag agaagatagt
181 ttcgtgtggt acatggataa tccacagaac ctaccttctg gatcatcacg tgttggagcc
241 attaagctta cctacatttc aaaggttagc gatgctacta agctaaggcc aaaggcggag
301 ttctgttttg ttatgaatgc aggaatgagg aagtacttcc tacaagccaa tgatcagcag
361 gacctagtgg aatgggtaaa tgtgttaaac aaagctataa aaattacagt accaaagcag
421 tcagactcac agcctaattc tgataaccta agtcgccatg gtgaatgtgg gaaaaagcaa
481 gtgtcttaca gaactgatat tgttggtggc gtacccatca ttactcccac tcagaaagaa
541 gaagtaaatg aatgtggtga aagtattgac agaaataatc tgaaacggtc acaaagccat
601 cttccttact ttactcctaa accacctcaa gatagtgcgg ttatcaaagc tggatattgt
661 gtaaaacaag gagcagtgat gaaaaactgg aagagaagat attttcaatt ggatgaaaac
721 acaataggct acttcaaatc tgaactggaa aaggaacctc ttcgcgtaat accacttaaa
781 gaggttcata aagtccagga atgtaagcaa agcgacataa tgatgaggga caacctcttt
841 gaaattgtaa caacgtctcg aactttctat gtgcaggctg atagccctga agagatgcac
901 agttggatta aagcagtctc tggcgccatt gtagcacagc ggggtcccgg cagatctgcg
961 tcttctgagc atccccccgg tccttcagaa tccaaacacg ctttccgtcc taccaacgca
1021 gccgccgcca cctcacattc cacagcctct cgcagcaact ctttggtctc aacctttacc
1081 atggagaagc gaggatttta cgagtctctt gccaaggtca agccagggaa cttcaaggtc
1141 cagactgtct ctccaagaga accagcttcc aaagtgactg aacaagctct gttaagacct
1201 caaagtaaaa atggccctca ggaaaaagat tgtgacctag tagacttgga cgatgcgagc
1261 cttccggtca gtgacgtgtg aggcagaagc gcacggagcc tgcctgcctc tgccgtcctc
1321 agttaccttt catgaggctt ctagccaaag atgataaagg gggaaatggt ttttagtgcg
1381 tatattatac tgcctcttag gtgtactctt
//