LOCUS AF284766 2454 bp mRNA linear HUM 02-MAY-2001
DEFINITION Homo sapiens kelch-like protein KLHL4c mRNA, complete cds,
alternatively spliced.
ACCESSION AF284766
VERSION AF284766.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2454)
AUTHORS Braybrook,C., Warry,G., Howell,G., Arnason,A., Bjornsson,A.,
Moore,G.E., Ross,M.T. and Stanier,P.
TITLE Identification and characterization of KLHL4, a novel human
homologue of the Drosophila Kelch gene that maps within the
X-linked cleft palate and Ankyloglossia (CPX) critical region
JOURNAL Genomics 72 (2), 128-136 (2001)
PUBMED 11401425
REFERENCE 2 (bases 1 to 2454)
AUTHORS Braybrook,C., Warry,G., Howell,G., Richardson,M., Arnason,A.,
Bjornsson,A., Ross,M.A., Moore,G.E. and Stanier,P.
TITLE Direct Submission
JOURNAL Submitted (09-JUN-2000) Institute of Reproductive and Developmental
Biology, Queen Charlotte's and Chelsea Hospital, Imperial College
Hammersmith Campus, Du Cane Road, London W12 0NN, UK
FEATURES Location/Qualifiers
source 1..2454
/db_xref="H-InvDB:HIT000076243"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq21.3"
CDS 90..2252
/note="similar to Drosophila kelch protein deposited in
GenBank Accession Number Q04652 and to Homo sapiens mayven
deposited in GenBank Accession Number AF059569; contains
POZ (BTB) domain and kelch repeats; alternatively spliced"
/codon_start=1
/product="kelch-like protein KLHL4c"
/protein_id="AAK49442.1"
/translation="MSVSGKKEFDVKQILRLRWRWFSHPFQGSTNTGSCLQQEGYEHR
GTPVQGRLKSHSRDRNGLKKSNSPVHHNILAPVPGPAPAHQRAVQNLQQHNLIVHFQA
NEDTPKSVPEKNLFKEACEKRAQDLEMMADDNIEDSTARLDTQHSEDMNATRSEEQFH
VINHAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEA
KQEEVRMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLI
KQLHPSNCLGIRSFGDAQGCTELLNVAHKYTMEHFIEVIKNQEFLLLPANEISKLLCS
DDINVPDEETIFHALMQWVGHDVQNRQGELGMLLSYIRLPLLPPQLLADLETSSMFTG
DLECQKLLMEAMKYHLLPERRSMMQSPRTKPRKSTVGALYAVGGMDAMKGTTTIEKYD
LRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGRDGLKTLNTVECFNPVGKIWTVMPP
MSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVV
ALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGG
HDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHT
YLNTVESYDAQRNEWKESMQELLQNFYTTQKLKETLGH"
BASE COUNT 731 a 502 c 580 g 641 t
ORIGIN
1 gctctaaagg aagaggcaga aaaacaagag ataacaaagg ctccgtttcc tttctgtgag
61 agaaggcttt tgtctttcct cctgctacga tgtcagtgtc tggcaagaaa gagtttgatg
121 tgaaacagat cctaaggcta cgctggaggt ggtttagtca tccttttcaa ggttccacca
181 acactggaag ctgtcttcag caggaaggat atgagcatag agggaccccg gttcagggca
241 ggttgaagag ccactctcgg gacagaaacg gactgaagaa aagcaacagt cctgtccacc
301 acaatatact ggcaccagtg ccaggaccgg cccctgccca tcagagagcc gttcagaatt
361 tgcagcaaca taatctgata gtacattttc aagcaaatga agatactcct aaatcagttc
421 cagagaagaa tttattcaaa gaagcttgtg agaaacgcgc acaagatttg gagatgatgg
481 ctgatgacaa tatagaagat tctacagcaa gattagatac acaacactct gaagacatga
541 atgccaccag atctgaagag cagttccatg ttataaacca cgcagagcaa actcttcgta
601 aaatggagaa ctacttgaaa gagaaacaac tatgtgatgt gctactgatt gcaggacacc
661 tccgcatccc agcccatagg ttggttctca gcgcagtgtc tgattatttt gctgcaatgt
721 ttactaatga tgtgcttgaa gccaaacaag aagaggtcag gatggaagga gtagatccaa
781 atgcactaaa ttccttggtg cagtatgctt acacaggagt cctgcaattg aaagaagata
841 ccattgaaag tttgctggct gcagcttgtc ttctgcagct gactcaggtc attgatgttt
901 gctccaattt tctcataaag cagctccatc cttcaaactg cttagggatt cgatcatttg
961 gagatgccca aggctgtaca gaacttctga acgtggcaca caaatacact atggaacact
1021 tcattgaggt aataaaaaac caagaattcc tcctgcttcc agctaatgaa atttcaaaac
1081 ttctgtgcag tgatgacatt aatgtgcctg atgaagagac catttttcat gctctaatgc
1141 agtgggtggg gcatgatgtg cagaataggc aaggagaact ggggatgctg ctttcttaca
1201 tcagactgcc attactccca ccacagttac tggcagatct tgaaaccagt tccatgttta
1261 ctggtgatct tgagtgtcag aagctcctga tggaagctat gaagtatcat cttttgcctg
1321 agagaagatc catgatgcaa agccctcgga caaagcctag aaaatcaact gtgggggcac
1381 tttatgctgt aggaggcatg gatgctatga aaggtactac tactattgaa aaatatgacc
1441 tcaggaccaa cagttggcta catattggca ccatgaatgg ccgtaggctt caatttggag
1501 tcgcagttat tgataataag ctctatgtcg tgggaggaag agacggttta aaaactttga
1561 atacagtgga atgttttaat ccagttggca aaatctggac tgtgatgcct cccatgtcaa
1621 cacatcggca cggcttaggt gtagccactc ttgaaggacc aatgtatgct gtaggtggtc
1681 atgatggatg gagctatcta aatactgtag aaagatggga ccctgaggga cgacagtgga
1741 attacgtagc cagtatgtca actcctagaa gcacagttgg tgttgttgca ttaaacaaca
1801 aattatatgc tattggtgga cgtgatggaa gttcctgcct caaatcaatg gaatactttg
1861 acccacacac taacaagtgg agtttgtgtg ctccaatgtc caaaagacgt ggaggtgtgg
1921 gagttgccac atacaatgga ttcttatatg ttgtaggggg gcatgatgcc cctgcttcca
1981 accattgctc caggctttct gactgtgtgg aacggtatga tccaaaaggt gattcatggt
2041 caactgtggc acctctgagt gttcctcgag atgctgttgc tgtgtgccct cttggagaca
2101 aactctacgt ggttggagga tatgacggac atacttattt gaacacagtt gagtcatatg
2161 atgcacagag aaatgaatgg aaagagagca tgcaagaact tctacaaaac ttctatacca
2221 cacagaagct gaaagagact ctggggcact aaattcagat cctttctcca cacagcaatg
2281 acatttatca atctgactca ggtgtggctg ttgccccttt ttgatatgga gggaacactg
2341 aaagacagtt tccttctgga gttccaaatg caatatagaa aaaaaaaccc tgtgactctg
2401 gattttattt taagttctct aacaagactc ctaccttgag atcttagtct aggt
//