LOCUS AF284756 3745 bp mRNA linear HUM 24-FEB-2003
DEFINITION Homo sapiens VPS10 domain receptor SorCS mRNA, complete cds.
ACCESSION AF284756
VERSION AF284756.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3745)
AUTHORS Hermey,G., Keat,S.J., Madsen,P., Jacobsen,C., Petersen,C.M. and
Gliemann,J.
TITLE Characterization of sorCS1, an alternatively spliced receptor with
completely different cytoplasmic domains that mediate different
trafficking in cells
JOURNAL J. Biol. Chem. 278 (9), 7390-7396 (2003)
PUBMED 12482870
REFERENCE 2 (bases 1 to 3745)
AUTHORS Hermey,G.
TITLE Sequence of the human SorCS gene
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3745)
AUTHORS Hermey,G.
TITLE Direct Submission
JOURNAL Submitted (03-JUL-2000) Medical Biochemistry, University of Aarhus,
Ole Worms Alle, Bldg. 170, Aarhus DK-8000-C, Denmark
FEATURES Location/Qualifiers
source 1..3745
/db_xref="H-InvDB:HIT000076241"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
CDS 9..3515
/note="contains VPS10 domain"
/codon_start=1
/product="VPS10 domain receptor SorCS"
/protein_id="AAL56667.1"
/translation="MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPS
SAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVA
ARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRL
TSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYE
KLNDKVGLKTILGYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQS
LLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHL
EARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYV
SYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTL
ALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDYQVKTFITYNKGRDWRLLQAPD
TDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELSDTDI
SMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYS
FTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQ
LHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEPCVCTEADFDCDYGYERHSNG
QCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPR
GLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIK
HVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLW
PSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAV
YEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPT
TAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTA
APLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALPSPPSPSTQPGDSSLRLQ
RARHATPPSTPKRGSAGAQYAI"
BASE COUNT 964 a 958 c 982 g 841 t
ORIGIN
1 ctcccgcgat gggaaaagtt ggcgccggcg gcggctccca agcccggctg agcgcgctcc
61 tcgccggcgc ggggctcttg atcctctgcg ccccgggcgt ctgcggcggc ggctcctgct
121 gcccctcgcc gcaccccagc tccgctccac gctcggcctc gacccctagg ggcttttccc
181 accaggggcg gccaggcagg gctcctgcca cgcccctgcc cctcgtagtg cgtcccctgt
241 tctcagtggc ccccggggac cgagcgctat ccctggagcg ggctcggggc actggggcat
301 ccatggcggt tgctgcacgc tccggccgga ggagacggag cggagcggat caggagaagg
361 cagaacgggg agagggcgcg agtcggagcc cccggggagt gctaagagat ggagggcagc
421 aggagcctgg gactcgggag cgggacccgg acaaagccac ccgcttccgg atggaggaac
481 tgagactgac cagcaccacg tttgcgctga cgggagactc agcacacaac caagccatgg
541 tccactggtc tggccacaac agcagcgtga ttctcatttt gacaaagctc tatgactata
601 acctggggag catcacagag agctcgcttt ggaggtcaac cgattatgga acaacctatg
661 agaagctgaa tgataaagtt ggtttgaaaa ccattttggg ctatctctat gtgtgtccta
721 ccaacaagcg taagataatg ttactcacag acccggagat tgagagcagt ttattgatca
781 gctcagatga aggggcaact tatcaaaagt accggctgaa cttctacatt caaagcttgc
841 tttttcaccc caaacaagaa gactggattc tggcatacag tcaagaccaa aagttataca
901 gctctgctga atttgggaga agatggcagc ttatccaaga aggggttgta ccaaacaggt
961 tctactggtc tgtgatgggg tcaaataaag aaccagacct tgtgcatctt gaggccagaa
1021 ctgtggatgg tcattcacat tatctaactt gccgaatgca gaactgtaca gaggccaaca
1081 ggaatcagcc ttttccaggc tacattgacc cagactcttt gattgttcag gatcattatg
1141 tgtttgttca gctgacatca ggagggcggc cacattacta cgtgtcctac cgaaggaatg
1201 catttgccca aatgaagctt ccgaaatatg ctttgcccaa ggacatgcat gttatcagca
1261 ccgatgagaa tcaggtgttc gcagcggtcc aagaatggaa ccagaatgac acgtacaacc
1321 tctacatctc agacacacgt ggtgtctact tcaccctggc cttggagaat gtccagagca
1381 gcagaggccc tgagggcaac atcatgatcg acctctatga ggtagcaggg ataaagggaa
1441 tgttcttggc aaacaagaag attgactacc aagtgaagac tttcatcaca tataacaaag
1501 gcagagactg gcgtttgctg caggcgccgg acacggatct aaggggggac cccgtgcact
1561 gcttgctgcc ctattgctca ctacaccttc acctgaaggt ctctgagaat ccctacacat
1621 cagggatcat tgccagcaaa gacacagctc caagcatcat agtggcatca ggtaatatag
1681 gttctgaatt gtcagacact gacatcagca tgtttgtctc ttcagatgca gggaacacct
1741 ggagacagat ctttgaagaa gagcacagtg ttttgtacct ggatcaaggt ggagtcctgg
1801 ttgctatgaa acacacatct ctcccaattc gacatctttg gttgagtttt gatgaaggga
1861 gatcttggag caaatacagt ttcacatcta ttccactttt tgtggatggg gtcctggggg
1921 agcctggaga agagactctc atcatgacag tgtttggaca cttcagccac cgctctgaat
1981 ggcagctggt caaagtagat tacaagtcca tttttgatag acggtgtgcc gaagaggact
2041 acagaccttg gcagctgcac agccaggggg aagcatgtat catgggagca aaaaggatat
2101 ataagaagcg aaaatcagag cggaagtgta tgcaaggaaa atatgcagga gctatggaat
2161 ctgaaccctg tgtctgcact gaggctgatt ttgattgcga ctatggttat gagcgacaca
2221 gcaatggcca gtgcctgccg gcattttggt tcaatccatc ctctctgtca aaggattgca
2281 gcttgggaca gagttacctc aatagtactg ggtacaggaa ggtggtttcc aataattgca
2341 ctgatggcgt aagggaacag tacactgcca aaccgcagaa gtgcccaggg aaagccccgc
2401 gggggctgcg gatagtcacg gctgatggaa agctgacagc ggaacaagga cacaacgtca
2461 ctctcatggt gcaattagaa gagggtgatg ttcagcggac actcatccaa gtggactttg
2521 gcgatggtat cgcggtgtct tacgtcaatc tcagctccat ggaagatggg atcaaacacg
2581 tctatcagaa cgtgggcatt ttccgtgtga ccgtgcaggt ggacaacagt ctgggttctg
2641 acagcgccgt cctgtactta catgtaactt gtcccttgga gcacgtgcac ctgtctcttc
2701 cctttgtcac cacaaagaac aaagaggtca atgcgacggc agtgctgtgg cccagccaag
2761 tgggcaccct cacttacgtg tggtggtacg gaaacaacac ggagcctttg atcaccttgg
2821 agggaagcat atccttcaga tttacttcag aaggaatgaa taccatcaca gtgcaggtct
2881 cagctgggaa tgccatccta caagacacaa agaccatcgc agtatatgag gaattccggt
2941 ctcttcgctt gtccttttct ccaaacctgg atgactacaa cccggacatc cctgagtgga
3001 ggagggacat cggtcgagtc atcaaaaaat ccctggtgga agccacaggg gttccaggcc
3061 agcacatcct ggtggcggtg ctccctggct tacccaccac tgctgaactc tttgtcctac
3121 cctatcagga tccagctgga gaaaacaaaa ggtcaactga tgacctggag cagatatcag
3181 aattgctgat ccacacgctc aaccaaaact cagtacactt cgagctgaag ccaggagtcc
3241 gagtccttgt ccatgctgct cacttaacag cggcccccct ggtggacctc actccaaccc
3301 acagtggatc tgccatgctg atgctgctct cagtggtgtt tgtggggctg gcagtgttcg
3361 tcatctacaa gtttaaaagg agagtagctt taccctcccc tccctcccct tctactcaac
3421 ctggtgactc atctctccga ttgcaaagag caagacacgc cactccgcct tcaacgccaa
3481 agcggggatc tgctggggca cagtatgcaa tttaaggaaa acccccaaag gctacaggcg
3541 acctgctgat caggaaagaa tttcgctctt gtcaagtaca tcatccttca tgaccactaa
3601 ctttgtgttt tttttctttc ctttgttgtt ctgtttccta ttttgccagg aagtatttcc
3661 atagttgctg agaatcaaag cacaaaagaa atccctacct atgtaaatgt ttgaatggag
3721 gacgccagta aaaaaaaaaa aaaaa
//