LOCUS AF283645 2534 bp mRNA linear HUM 05-DEC-2000
DEFINITION Homo sapiens folate transporter/carrier mRNA, complete cds; nuclear
gene for mitochondrial product.
ACCESSION AF283645
VERSION AF283645.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2534)
AUTHORS Titus,S.A. and Moran,R.G.
TITLE Retrovirally mediated complementation of the glyB phenotype.
Cloning of a human gene encoding the carrier for entry of folates
into mitochondria
JOURNAL J. Biol. Chem. 275 (47), 36811-36817 (2000)
PUBMED 10978331
REFERENCE 2 (bases 1 to 2534)
AUTHORS Titus,S.A. and Moran,R.G.
TITLE Direct Submission
JOURNAL Submitted (29-JUN-2000) Pharmacology and Toxicology, Medical
College of Virginia, 1101 E. Marshall, Richmond, VA 23298-0230, USA
FEATURES Location/Qualifiers
source 1..2534
/db_xref="H-InvDB:HIT000076171"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q21"
CDS 129..1076
/note="MFT; six transmembrane domain transport protein;
member of mitochondrial metabolite transporters/carriers
family"
/codon_start=1
/product="folate transporter/carrier"
/protein_id="AAG37834.1"
/translation="MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLD
LVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFF
YNAIKSYKTEGRAEHLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPH
RQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLP
EAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVG
GFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK"
BASE COUNT 718 a 512 c 533 g 771 t
ORIGIN
1 gagtcctctc gttggtcccg gaggtggggt tgcgctcaca aggggcgacc gtcgccacgg
61 tggcggccac tgcatcgcgt cccacctccg cggccctggg cgccgtggtg tcgacgggcc
121 ccgagcctat gacgggccag ggccagtcgg cgtccgggtc gtcggcgtgg agcacggtat
181 tccgccacgt ccggtatgag aacctgatag cgggcgtgag cggcggcgtc ttatccaacc
241 ttgcgctgca tccgctcgac ctcgtgaaga tccgcttcgc cgtgagtgat ggattggaac
301 tgagaccgaa atataatgga attttacatt gcttgactac catttggaaa cttgatggac
361 tacggggact ttatcaagga gtaaccccaa atatatgggg tgcaggttta tcctggggac
421 tctacttttt cttttacaat gccatcaagt catataaaac agaaggaaga gctgaacatt
481 tagaggcaac agaatacctt gtctcagctg ctgaagctgg agccatgacc ctctgcatta
541 caaacccatt atgggtaaca aaaactcgcc ttatgttaca gtatgatgct gttgttaact
601 ccccacaccg acaatataaa ggaatgtttg atacacttgt gaaaatatat aagtatgaag
661 gtgtgcgtgg attatataag ggatttgttc ctgggctgtt tggaacatcg catggtgccc
721 ttcagtttat ggcatatgaa ttgctgaagt tgaagtacaa ccagcatatc aatagattac
781 cagaagccca gttgagcaca gtagaatata tatctgttgc agcactatcc aaaatatttg
841 ctgtcgcagc aacataccca tatcaagtcg taagagctcg tcttcaggat caacacatgt
901 tttacagtgg tgtaatagat gtaatcacaa agacatggag gaaagaaggc gtcggtggat
961 tttacaaggg aattgctcct aatttgatta gagtgactcc agcctgctgt attacctttg
1021 tggtatatga aaacgtctca cattttttac ttgaccttag agaaaagaga aagtaagctc
1081 aaagaggaca attccagtat atctgcccaa ggcagcaaca agctcttttg tgtttaaggc
1141 ataaaagaag aattctgcat agaaacatgg ctcatattcg aaattgctct atagtcatta
1201 gaagccagag aactgctaag tctcctgcaa tgtttttctt gctttttgcc ttccccatat
1261 atatggaact tggctacctc tgcctgaaat ggctgccatc aacacaatgt taaaactgac
1321 acgaaggata gagtttcaca gatttctacg ttttattggt ggaagctgat ttgcaacatt
1381 tgctaaatgg attagatgaa tgtacttctt tttgtgagct tacttgcctg gattgcttta
1441 aaattaacct ttgtgcaata ccaagaaaat agctctttaa aagaatgtct ttgtatgtct
1501 caaggtaaat taaggattta ctgaataagg tgttgaccaa atccagacca ttttatttta
1561 tttttttatt tatttatttt ttgagatgga gtcttgcttt gtcgcccagg ctggagtgca
1621 gtggcgtgat ctcagctcac tgcaacctcc acctcccggg ttcacgccat tctcctgcct
1681 cagcctcctg agtagctggg actacaggca cctgccacca cgcctggcta actttttttt
1741 atattttgag tagaaatggg gtttcaccat gttagccagg atggtctcaa tctcctgacc
1801 ttgtgatccg cctgccttgg cctcccaaag tgctgggatt acaggcgtga gccactgcgc
1861 ctggccagac cattttagaa ttgggaaatt ttagtgagaa aaaatgcact gtaaatatgc
1921 tttagtttta attcagttgg gatgcactac ctagcgaaaa ttgagaaact atatacttct
1981 cagagaaata tctgacatct attgtcattc cattgctatt ttttttcccc agagacttcc
2041 ataatttaaa ataaaatcct agatccagtt cttgtttttt ggcataaata cttaatctat
2101 tttaaattta taaaatctga gcttctagga tccagctgtg tcaaccttta tttagcatat
2161 ataactataa atcacttatt acagatgcta aatagatcac cttttacaga tgctgaaatg
2221 tttgggatat gtttgttgac aaggtaaatg gaaatgagaa actttatact tcagttttca
2281 gatatatgga tctagatccc aaataaatga ttaatcttca ttggtttctc aaattcaggt
2341 tgaaatacaa attaatagcc tttattgatt ttacttttat gagtcattgt agacatctat
2401 aaatataaaa gggcctgtac ccaaaggatg ccagaatact agtattttta tttatcgtaa
2461 acatccacga gtgctgttgc actaccatct atttgttgta aataaaagtg ttgttttcaa
2521 aaaaaaaaaa aaaa
//