LOCUS AF283301 2319 bp mRNA linear HUM 16-JUL-2001
DEFINITION Homo sapiens chronic myelogenous leukemia tumor antigen 66 mRNA,
complete cds, alternatively spliced.
ACCESSION AF283301
VERSION AF283301.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2319)
AUTHORS Yang,X.F., Wu,C.J., McLaughlin,S., Chillemi,A., Wang,K.S.,
Canning,C., Alyea,E.P., Kantoff,P., Soiffer,R.J., Dranoff,G. and
Ritz,J.
TITLE CML66, a broadly immunogenic tumor antigen, elicits a humoral
immune response associated with remission of chronic myelogenous
leukemia
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (13), 7492-7497 (2001)
PUBMED 11416219
REFERENCE 2 (bases 1 to 2319)
AUTHORS Yang,X.-F., Wu,C.J. and Ritz,J.
TITLE Direct Submission
JOURNAL Submitted (28-JUN-2000) Adult Oncology, Dana-Farber Cancer
Institute, 44 Binney Street, Mayer 530, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2319
/db_xref="H-InvDB:HIT000076160"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 233..1984
/note="CML66; alternatively spliced"
/codon_start=1
/product="chronic myelogenous leukemia tumor antigen 66"
/protein_id="AAK73017.1"
/translation="MEVAANCSLRVKRPLLDPRFEGYKLSLEPLPCYQLELDAAVAEV
KLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVMLDTALGKPREVF
RLPTDLTACDNRLCASIHFSSSTWVTLSDGTGRLYVIGTGERGNSASEKWEIMFNEEL
GDPFIIIHSISLLNAEEHSIATLLLRIEKEELDMKGSGFYVSLEWVTISKKNQDNKKY
EIIKRDILRGKSVPHYAAIEPDGNGLMIVSYKSFTFVQAGQDLEENMDEDVSEKIKEP
LYYWQQTEDDLTVTIRLPEDSTKEDIQIQFLPDHINIVLKDHQFLEGKLYSSIDHESS
TWIIKESNSLEISLIKKNEGLTWPELVIGDKQGELIRDSAQCAAIAERLMHLTSEELN
PNPDKEKPPCNAQELEECDIFFEESSSLCRFDGNTLKTTHVVNLGSNQYLFSVIVDPK
EMPCFCLRHDVDALLWQPHSSKQDDMWEHIATFNALGYVQASKRDKKFFACAPNYSYA
ALCECLRRVFIYRQPAPMSTVLYNRKEGRQVGQVAKQQVASLETNDPILGFQATNERL
FVLTTKNLFLIKVNTEN"
BASE COUNT 725 a 432 c 493 g 669 t
ORIGIN
1 aacagagttc agaccttgcc gtcgcgcgcg cgttaagtac caggagaact acatagccca
61 gcatgcaaca gtctcaactt tttcacggac actacatttc ccagaaggca gttcgcaccg
121 cagtgttttc tgggatggga accacgccgc ttcccagtct ctgtgcgagg cgtgaagcgc
181 ggacctttca acaagggctt tattaattct cacgctgcgg ccctggaaag cgatggaggt
241 ggcggctaat tgctccctac gggtgaagag acctctgttg gatccccgct tcgagggtta
301 caagctctct cttgagccgc tgccttgtta ccagctggag cttgacgcag ctgtggcaga
361 ggtaaaactt cgagatgatc aatatacact ggaacacatg catgcttttg gaatgtataa
421 ttacctgcac tgtgattcat ggtatcaaga cagtgtctac tatattgata cccttggaag
481 aattatgaat ttaacagtaa tgctggacac tgccttagga aaaccacgag aggtgtttcg
541 acttcctaca gatttgacag catgtgacaa ccgtctttgt gcatctatcc atttctcatc
601 ttctacctgg gttaccttgt cagatggaac tggaagattg tatgtcattg gaacaggtga
661 acgtggaaat agcgcttctg aaaaatggga gattatgttt aatgaagaac ttggggatcc
721 ttttattata attcacagta tctcactgct aaatgctgaa gaacattcta tagctaccct
781 acttcttcga atagagaaag aggaattgga tatgaaagga agtggtttct atgtttctct
841 ggagtgggtc actatcagta agaaaaatca agataataaa aaatatgaaa ttattaagcg
901 tgatattctc cgtggaaagt cagtgccaca ttatgctgct attgagcctg atggaaatgg
961 tctaatgatt gtatcctaca agtctttcac atttgttcag gctggtcaag atcttgaaga
1021 aaatatggat gaagacgtat cagagaaaat caaagaacct ctgtattact ggcaacagac
1081 tgaagatgat ttgacagtaa ccatacggct tccagaagac agtactaagg aggacattca
1141 aatacagttt ttgcctgatc acatcaacat tgtactgaag gatcaccagt ttttagaagg
1201 aaaactctat tcatctattg atcatgaaag cagtacatgg ataattaaag agagtaatag
1261 cttggagatt tccttgatta agaagaatga aggactgacc tggccagagc tagtaattgg
1321 agataaacaa ggggaactta taagagattc agcccagtgt gctgcaatag ctgaacgttt
1381 gatgcatttg acctctgaag aactgaatcc aaatccagat aaagaaaaac caccttgcaa
1441 tgctcaagag ttagaagaat gtgatatttt ctttgaagag agctccagtt tatgcagatt
1501 tgatggcaat acattaaaaa ctactcatgt ggtgaatctt ggaagcaacc agtacctttt
1561 ctctgtcata gtggatccta aagaaatgcc ctgcttctgt ttgcgccatg atgttgatgc
1621 cctactctgg caaccacact ccagcaaaca agatgatatg tgggagcaca tcgcaacttt
1681 caatgcttta ggctatgtcc aagcatcaaa gagagacaaa aaattttttg cctgtgctcc
1741 aaattactcg tatgcagccc tttgtgagtg ccttcgtcga gtattcatct atcgtcagcc
1801 tgctcccatg tccactgtac tttacaacag aaaggaaggc aggcaagtag gacaggttgc
1861 taagcagcaa gtagcaagcc tagaaaccaa tgatcctatt ttaggatttc aggcaacaaa
1921 tgagagatta tttgttctta ctaccaaaaa cctcttttta ataaaagtaa atacagagaa
1981 ttaattattc taacatattg gcctctttgt actggaaaag tattcagtgg tacctggagg
2041 tctggacagt tatactgtaa cctcttaagt tttaatgtgc taaatatatc ttgtatgatt
2101 ttttattttt taataacatt ggaaatatat tcaagagatt atgattctgt aaagctgtgg
2161 aatgaagctg cagatttaga gaacattggc ttctgaaaaa aaaaagagtg aagatagtac
2221 tagcaagtat acttattttt taaaacaggc tagaatctca tgttttatat gaaagatgta
2281 caattcagtg tttaaaaata aaaatattta ttgtgtaaa
//