LOCUS AF282265 3536 bp mRNA linear HUM 26-JUL-2001
DEFINITION Homo sapiens inner centromere protein INCENP mRNA, complete cds.
ACCESSION AF282265
VERSION AF282265.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3536)
AUTHORS Adams,R.R., Eckley,D.M., Vagnarelli,P., Wheatley,S.P.,
Gerloff,D.L., Mackay,A.M., Svingen,P.A., Kaufmann,S.H. and
Earnshaw,W.C.
TITLE Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on
chromosomes and is overexpressed in tumour cells
JOURNAL Chromosoma 110 (2), 65-74 (2001)
PUBMED 11453556
REFERENCE 2 (bases 1 to 3536)
AUTHORS Adams,R.R., Eckley,D.M., Mackay,A. and Earnshaw,W.C.
TITLE Characterization and expression of the human INCENP gene
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3536)
AUTHORS Adams,R.R., Eckley,D.M., Mackay,A. and Earnshaw,W.C.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-2000) Institute of Cell and Molecular Biology,
University of Edinburgh, Kings Buildings, Mayfield Rd, Edinburgh,
Scotland EH9 3JR, UK
FEATURES Location/Qualifiers
source 1..3536
/db_xref="H-InvDB:HIT000076141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q12-13"
/cell_line="HeLa"
CDS 1..2760
/note="chromosomal passenger"
/codon_start=1
/product="inner centromere protein INCENP"
/protein_id="AAF87584.1"
/translation="MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERM
FTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLR
SKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNH
TQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEES
TPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSP
WRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRR
ASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEV
PENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRK
RSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTP
TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV
KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA
AKKMEEVEARRKQEEDARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE
QREQERREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE
REKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQ
SPACTSSPITPQGHKAPPQINPHNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAI
IHQYYQPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQGARVPSSLAY
SLKKH"
BASE COUNT 824 a 993 c 1129 g 590 t
ORIGIN
1 atggggacga cggccccagg gcccattcac ctgctggagc tatgtgacca gaagctcatg
61 gagtttctct gcaacatgga taataaggac ttggtgtggc ttgaggagat ccaagaggag
121 gccgagcgca tgttcaccag agaattcagc aaagagccag agctgatgcc caaaacacct
181 tctcagaaga accgacggaa gaagagacgg atttcttatg ttcaggatga aaacagagat
241 cccatcagga gaaggttatc ccgcagaaag tctcggagca gccagctgag ctcccgacgc
301 ctccgcagca aggacagtgt agagaagctg gctacagtgg tcggggagaa cggctccgtt
361 ctgcggcgtg tgacccgtgc tgcggctgca gctgccgcgg ctaccatggc attggctgca
421 ccttcttcac ccacccctga gtctcccacg atgctgacta agaagcccga ggataaccac
481 acccagtgcc agctggtgcc tgtggtggag atcggcatca gtgagcgcca gaatgctgag
541 cagcatgtca cccagctcat gtccaccgag cctctgcccc gcactctgtc cccgactcca
601 gcttcagcca cagctccaac ctcccagggc atcccgacat cagatgagga atcaacacct
661 aagaagtcga aggccaggat actggagtcc atcacagtga gctccctgat ggctacaccc
721 caggacccca agggtcaagg ggtcgggacg gggcggtctg cgtctaagct caggattgcg
781 caggtctccc ctggcccacg ggactcgcca gcctttccag attctccatg gcgggagcgg
841 gtgctggctc ccatcctgcc ggataacttc tccacgccca cgggctctcg cacggactct
901 caatcggtgc ggcacagccc gatcgccccg tcttccccga gtccccaagt cttagcccag
961 aagtactctc tggtggccaa acaggaaagt gttgtccgca gggcgagcag aaggcttgcc
1021 aagaagactg ccgaagagcc agctgcctct ggccgcatca tctgtcacag ttacctggag
1081 aggctcctga atgttgaggt gccccagaaa gttggttctg agcagaagga accccccgag
1141 gaggctgagc ctgtggcggc agctgagcca gaggtccctg agaacaacgg aaataactcg
1201 tggccccaca atgacacgga gattgccaac agcacaccca acccgaagcc tgcagccagc
1261 agcccggaaa caccctctgc agggcagcaa gaggccaaga cggaccaagc agatggaccc
1321 agagagccac cgcagagtgc caggaggaag cgcagctaca agcaggccgt gagtgagctg
1381 gacgaggagc agcacctgga ggatgaggag ctgcagcccc ccaggagcaa gaccccttcc
1441 tcaccctgcc cagccagcaa ggtggtacgg cccctccgga cctttctgca cacagtgcag
1501 aggaaccaga tgctcatgac ccctacctca gccccacgca gcgtcatgaa gtcctttatt
1561 aagcgcaaca ctcccctgcg catggacccc aaggagaagg agcggcagcg cctggagaat
1621 ctgcggcgga aggaggaggc cgagcagctg cgcaggcaga aggtggagga ggacaagcgg
1681 cggcggctgg aggaggtgaa gctgaagcgt gaggaacgcc tccgcaaggt gctgcaggcc
1741 cgcgagcggg tggagcagat gaaggaggag aagaagaagc agattgagca gaagtttgct
1801 cagatcgacg agaagactga gaaggccaag gaggagcggc tggcagagga gaaggccaag
1861 aaaaaggcgg cggccaagaa gatggaggag gtggaagcac gcaggaagca ggaagaggat
1921 gcacgtaggc tcaggtggct gcagcaggag gaggaagagc ggcggcacca agagctgctg
1981 cagaagaaga aggaagagga gcaggagcgg ctgcggaagg cggccgaggc taagcggctg
2041 gcagagcagc gggagcagga gcggcgggag caggagcggc gggagcagga gcggcgcgag
2101 caggagcggc gcgagcagga gcggcgggag caggagcggc gcgagcagga gcgacagctg
2161 gcagagcagg agcgtcggcg ggagcaggag cggctccaag ccgagaggga gctgcaggag
2221 cgggagaagg ccctgcggct gcagaaggag cagctgcaga gggaactgga ggagaagaag
2281 aagaaggaag agcagcagcg tctggctgag cggcagctgc aggaggagca agagaagaaa
2341 gccaaggagg cagcaggggc cagcaaggcc ctgaatgtga ctgtggacgt gcagtctcca
2401 gcttgtacct catctcccat cactccgcaa gggcacaagg cccctcccca gatcaacccc
2461 cacaactacg ggatggatct gaatagcgac gactccaccg atgatgaggc ccatccccgg
2521 aagcccatcc ccacctgggc ccgaggcacc ccgctcagcc aggctatcat tcaccagtac
2581 taccagccac cgaaccttct ggagctcttt ggaaccattc tcccactgga cttggaggat
2641 atcttcaaga agagcaagcc ccgctatcac aagcgcacca gctctgctgt ctggaactca
2701 ccgcccctgc agggcgccag ggtccccagc agcctggcct acagcctgaa gaagcactga
2761 ggctggcctg cggccttctt ggcagcctcg cctcctgtcc atgtctatct gtctgtctgt
2821 cggtctgtgt cttggtctgt tgccctcctt cttggcatgc cattgtggag ggcttggcca
2881 ggtgtatata aacgtcctct gtgctgggtg tttctgctgc aggtggcagg tggccccagg
2941 cctgtttgga ggatgggctg ggtgggtggg tggggaagaa atgggcccag ccccacatgg
3001 cctgcagaca gtgctctgta aatagttgtt ttaatttagc tgaatgttag cattttagtc
3061 tttggcattt tagcgtttgg gaggtagatt aataaagtat attccttcaa gcctgctgtt
3121 gataccatga agactgggcg cctcagtccc agccctgtag ctgtgtgtct tgggccacca
3181 gtggcctgca ggacgaaggt actgttccat cacctgcggt gtgcctcagg atcaccaggt
3241 gcaggccccc accctcggag atgctgctgc agtgagtggt tccactgcct ggataaccct
3301 tgaggaacac gtcagttact gtcacgatgg ggcaggtgga gctccttcct attttttggg
3361 gtgctccctg tttgtaaagg ggagtttgtt cattgggaaa gacctgggtc ttgacacggc
3421 cctgccactt agtcccctac cctctccatt ccccaggctc cacccgtgct gctcaagtgc
3481 aaatggactt gagagtattt atgtgctggt gaagtatgag gtctgagtag aaaagg
//