LOCUS AF279144 2320 bp mRNA linear HUM 09-MAY-2001
DEFINITION Homo sapiens tumor endothelial marker 7 precursor (TEM7) mRNA,
complete cds.
ACCESSION AF279144
VERSION AF279144.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2320)
AUTHORS St. Croix,B., Rago,C., Velculescu,V., Traverso,G., Romans,K.E.,
Montgomery,E., Lal,A., Riggins,G.J., Lengauer,C., Vogelstein,B. and
Kinzler,K.W.
TITLE Genes expressed in human tumor endothelium
JOURNAL Science 289 (5482), 1197-1202 (2000)
PUBMED 10947988
REFERENCE 2 (bases 1 to 2320)
AUTHORS St. Croix,B., Vogelstein,B. and Kinzler,K.W.
TITLE Direct Submission
JOURNAL Submitted (16-JUN-2000) Johns Hopkins Oncology Center, Johns
Hopkins University, 1650 Orleans Street, Baltimore, MD 21231, USA
REFERENCE 3 (bases 1 to 2320)
AUTHORS St. Croix,B., Vogelstein,B. and Kinzler,K.W.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2001) Johns Hopkins Oncology Center, Johns
Hopkins University, 1650 Orleans Street, Baltimore, MD 21231, USA
REMARK Sequence update by submitter
COMMENT On May 9, 2001 this sequence version replaced AF279144.1.
FEATURES Location/Qualifiers
source 1..2320
/db_xref="H-InvDB:HIT000076037"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
gene 1..2320
/gene="TEM7"
CDS 83..1585
/gene="TEM7"
/note="TEM7 precursor"
/codon_start=1
/product="tumor endothelial marker 7 precursor"
/protein_id="AAG00869.2"
/translation="MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGW
NRRARESPGHVSEPDRTQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEP
HSRELWVDVAEANRSQVKIHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIF
MGDVIHRMLTATQYVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGS
FTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRS
IFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSG
FDRYRQEWMDYGCAQEAEGRMCEDFQDEDHDSASPDTSFSPYDGDLTTTSSSLFIDSL
TTEDDTKLNPYAGGDGLQNNLSPKTKGTPVHLGTIVGIVLAVLLVAAIILAGIYINGH
PTSNAALFFIERRPHHWPAMKFRSHPDHSTYAEVEPSGHEKEGFMEAEQC"
sig_peptide 83..136
/gene="TEM7"
/inference="non-experimental evidence, no additional
details recorded"
/note="predicted"
misc_feature 137..1582
/gene="TEM7"
/inference="non-experimental evidence, no additional
details recorded"
/note="predicted; Region: tumor endothelial marker 7"
misc_feature 1355..1423
/gene="TEM7"
/inference="non-experimental evidence, no additional
details recorded"
/note="predicted; Region: transmembrane domain"
BASE COUNT 563 a 669 c 596 g 492 t
ORIGIN
1 gcggccgcag cctgagccag ggccccctcc ctcgtcagga ccggggcagc aagcaggccg
61 ggggcaggtc cgggcaccca ccatgcgagg cgagctctgg ctcctggtgc tggtgctcag
121 ggaggctgcc cgggcgctga gcccccagcc cggagcaggt cacgatgagg gcccaggctc
181 tggatgggct gccaaaggga ccgtgcgggg ctggaaccgg agagcccgag agagccctgg
241 gcatgtgtca gagccggaca ggacccagct gagccaggac ctgggtgggg gcaccctggc
301 catggacacg ctgccagata acaggaccag ggtggtggag gacaaccaca gctattatgt
361 gtcccgtctc tatggcccca gcgagcccca cagccgggaa ctgtgggtag atgtggccga
421 ggccaaccgg agccaagtga agatccacac aatactctcc aacacccacc ggcaggcttc
481 gagagtggtc ttgtcctttg atttcccttt ctacgggcat cctctgcggc agatcaccat
541 agcaactgga ggcttcatct tcatggggga cgtgatccat cggatgctca cagctactca
601 gtatgtggcg cccctgatgg ccaacttcaa ccctggctac tccgacaact ccacagttgt
661 ttactttgac aatgggacag tctttgtggt tcagtgggac cacgtttatc tccaaggctg
721 ggaagacaag ggcagtttca ccttccaggc agctctgcac catgacggcc gcattgtctt
781 tgcctataaa gagatcccta tgtctgtccc ggaaatcagc tcctcccagc atcctgtcaa
841 aaccggccta tcggatgcct tcatgattct caatccatcc ccggatgtgc cagaatctcg
901 gcgaaggagc atctttgaat accaccgcat agagctggac cccagcaagg tcaccagcat
961 gtcggccgtg gagttcaccc cattgccgac ctgcctgcag cataggagct gtgacgcctg
1021 catgtcctca gacctgacct tcaactgcag ctggtgccat gtcctccaga gatgctccag
1081 tggctttgac cgctatcgcc aggagtggat ggactatggc tgtgcacagg aggcagaggg
1141 caggatgtgc gaggacttcc aggatgagga ccacgactca gcctcccctg acacttcctt
1201 cagcccctat gatggagacc tcaccactac ctcctcctcc ctcttcatcg acagcctcac
1261 cacagaagat gacaccaagt tgaatcccta tgcaggagga gacggccttc agaacaacct
1321 gtcccccaag acaaagggca ctcctgtgca cctgggcacc atcgtgggca tcgtgctggc
1381 agtcctcctc gtggcggcca tcatcctggc tggaatttac atcaatggcc accccacatc
1441 caatgctgcg ctcttcttca tcgagcgtag acctcaccac tggccagcca tgaagtttcg
1501 cagccaccct gaccattcca cctatgcgga ggtggagccc tcgggccatg agaaggaggg
1561 cttcatggag gctgagcagt gctgagaaca ccaagtctcc cctttgaaga ctttgaggcc
1621 acagaaaaga cagttaaagc aaagaagaga agtgactttt cctggcctct cccagcatgc
1681 cctgggctga gatgagatgg tggtttatgg ctccagagct gctgttcgct tcgtcagcac
1741 accccgaata ttgaagaggg ggccaaaaaa caaccacatg gattttttat aggaacaaca
1801 acctaatctc atcctgtttt gatgcaaggg ttctcttctg tgtcttgtaa ccatgaaaca
1861 gcagaagaac taacataact aactccattt ttgtttaagg ggcctttacc tattcctgca
1921 cctaggctag gataacttta gagcactgac ataaaacgca aaaacaggaa tcatgccgtt
1981 tgcaaaacta actctgggat taaaggggaa gcatgtaaac agctaactgt ttttgttaaa
2041 gatttatagg aatgaggagg tttggctatt gtcacatgac agactgttag ccaaggacaa
2101 agaagttctg caaacctccc ctggaccctt gctggtgtcc agatgtctgc ggttgtcagc
2161 cccttccttt cccccgacct aaacataaaa gacaaggcaa agcccgcata attttaagac
2221 ggttctttag gacattagtc caccatcttc ttggtttgct ggctctccga aataaagtcc
2281 ctttccttgc tccaaaaaaa aaaaaaaaaa aaaaaaaaaa
//