LOCUS AF277094 2900 bp mRNA linear HUM 12-JAN-2001
DEFINITION Homo sapiens ELOVL4 mRNA, complete cds.
ACCESSION AF277094
VERSION AF277094.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2900)
AUTHORS Zhang,K., Kniazeva,M., Han,M., Li,W., Yu,Z., Yang,Z., Li,Y.,
Metzker,M.L., Allikmets,R., Zack,D.J., Kakuk,L.E., Lagali,P.S.,
Wong,P.W., MacDonald,I.M., Sieving,P.A., Figueroa,D.J.,
Austin,C.P., Gould,R.J., Ayyagari,R. and Petrukhin,K.
TITLE A 5-bp deletion in ELOVL4 is associated with two related forms of
autosomal dominant macular dystrophy
JOURNAL Nat. Genet. 27 (1), 89-93 (2001)
PUBMED 11138005
REFERENCE 2 (bases 1 to 2900)
AUTHORS Petrukhin,K.
TITLE Elf, a new protein involved in elongation of fatty acids...
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2900)
AUTHORS Petrukhin,K.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2000) Pharmacology, Merck Research Labs, P.O. Box
4, West Point, PA 19486, USA
FEATURES Location/Qualifiers
source 1..2900
/db_xref="H-InvDB:HIT000075970"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q14"
CDS 148..1092
/function="involved in elongation of fatty acids"
/codon_start=1
/product="ELOVL4"
/protein_id="AAG47668.1"
/translation="MGLLDSEPGSVLNVVSTALNDTVEFYRWTWSIADKRVENWPLMQ
SPWPTLSISTLYLLFVWLGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSY
NAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVY
HHCTMFTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYL
TMLQLIQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYIRTYKEPKKP
KAGKTAMNGISANGVSKSEKQLMIENGKKQKNGKAKGD"
BASE COUNT 885 a 505 c 572 g 938 t
ORIGIN
1 tgaggagcag gagaagacgc agccgggccg ccgccgttag aggggttccc ggccgccgct
61 cgccccgtcg gccgccaccg cctccggggt cagccctctc tctgggtctc cgctttctcc
121 tgccgccagc gcccgctcat cgccgcgatg gggctcctgg actcggagcc gggtagtgtc
181 ctaaacgtag tgtccacggc actcaacgac acggtagagt tctaccgctg gacctggtcc
241 atcgcagata agcgtgtgga aaattggcct ctgatgcagt ctccttggcc tacactaagt
301 ataagcactc tttatctcct gtttgtgtgg ctgggtccaa aatggatgaa ggaccgagaa
361 ccttttcaga tgcgtctagt gctcattatc tataattttg ggatggtttt gcttaacctc
421 tttatcttca gagagttatt catgggatca tataatgcgg gatatagcta tatttgccag
481 agtgtggatt attctaataa tgttcatgaa gtcaggatag ctgctgctct gtggtggtac
541 tttgtatcta aaggagttga gtatttggac acagtgtttt ttattctgag aaagaaaaac
601 aaccaagttt ctttccttca tgtgtatcat cactgtacga tgtttacctt gtggtggatt
661 ggaattaagt gggttgcagg aggacaagca ttttttggag cccagttgaa ttcctttatc
721 catgtgatta tgtactcata ctatgggtta actgcatttg gcccatggat tcagaaatat
781 ctttggtgga aacgatacct gactatgttg caactgattc aattccatgt gaccattggg
841 cacacggcac tgtctcttta cactgactgc cccttcccca aatggatgca ctgggctcta
901 attgcctatg caatcagctt catatttctc tttcttaact tctacattcg gacatacaaa
961 gagcctaaga aaccaaaagc tggaaaaaca gccatgaatg gtatttcagc aaatggtgtg
1021 agcaaatcag aaaaacaact catgatagaa aatggaaaaa agcagaaaaa tggaaaagca
1081 aaaggagatt aaattgaact gggccttaac tgttgttgac agtgaggaaa aactcccata
1141 tcatataaaa tttcagggaa aacagaagca aaggagagct tgggggtggg gagaaaagac
1201 aaatgtgctc tatgtcctag taactcttag actgagtaaa gtgttaatac catacccaga
1261 tgttttattt atgaagtttt tattttaaac atttttttta aaaattagcc ttgatattct
1321 ccagaccaaa gcaatcatta agtgactttg gggattctcc ccctgttcac atccagttgt
1381 ctaaaggatg agatttttca tgtatcttat agtcactcat tcttcggtct gaattttaga
1441 cgatcacaga aacggtcttt atgaattatt ttgataaatt actaattatc ttatctactg
1501 actgaaatca gtggtgttac attttcttgt ccaaagctga aaatgtgtat acacttaaac
1561 ttgcacattt gaattcattt gctgaccgga atggtcaaat ctctccacct ctagtcagag
1621 tataattttg gttgtaatta aatttttaaa atctgctgat ctctgtagaa tcttagaggc
1681 ttgatgatga tggtgttggt gaaaataaga aagaattgca gtaaagtctt gtctggtgac
1741 ccagagatca ccatgacttg aggcacaaat cactgtgggg aaacaatttt ttgtgatgaa
1801 aaggcagcat ttgaatactc ctgttagtag cagaaatata ttatgaaatt aagattattg
1861 tctgattgaa acatgaaaca actcatgtct ttattagtaa catcataaga tagttacatt
1921 tatgtgctgt tagaatatgt taatttttat caggctttcc ttgttttgat ttatggctgt
1981 tcctgatttt tcatatgtgg aaatatacct acctcttccg ttggaaagaa catttaaaat
2041 taaataaatt ttaattaaaa aatcaaggag tcttctaatg taaattttaa tgttaacttt
2101 caaatccact agtatttttt ttgcttttat gacaaatagc atacaccaaa catttctgtg
2161 aaactatcct tctctttcaa tgtgtttaat tttggagtaa cgttttcctt gtgactaagt
2221 tgcaagatct tatttattaa ctaggtatga agtataaacc cattttggtg caatattctt
2281 gactccttgg tgctaaagat tgttaaattc aatgcttgat gttacaaggt gttgttaaaa
2341 cacaaaatga ataaaagtga gagtagtcag aactataaca ttcaatttgc tatttacaaa
2401 tgaagtattt catgtaatat aagtgaacaa ctggaaataa agtaggaaag aatttgtatc
2461 atgttttact acataggtta attttttaag ggatgttgca aagggattac tagagaaaga
2521 caaaatgtga ccaaaaaaaa gcatgaatat ttcttaagta tctcaacaac atgtcaaagc
2581 tgcatgtgta ggatgtatgc tgtttgtaca aactatttca gaatattttg taagctataa
2641 catatttatt gtgcattaaa attaaatact ttttccccaa aggcatgcag tcatgagaat
2701 tacagaaaat ttgcaacata taaagtagtt tgatctaaga ggattcaaca cctttgtttt
2761 gttgctcagt gtgtaatgac tgagatttgt aaatctttgt gaacattctg tactggttcc
2821 caagagctat tcattccctg ctacctgatt tcagcacaat aaatatactt ctgctgtggg
2881 aaaaaaaaaa aaaaaaaaaa
//