LOCUS AF274863 4648 bp mRNA linear HUM 07-MAR-2006
DEFINITION Homo sapiens secretory pathway component Sec31B-1 mRNA,
alternatively spliced, complete cds.
ACCESSION AF274863
VERSION AF274863.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4648)
AUTHORS Stankewich,M.C., Stabach,P.R. and Morrow,J.S.
TITLE Human Sec31B: a family of new mammalian orthologues of yeast Sec31p
that associate with the COPII coat
JOURNAL J. Cell. Sci. 119 (PT 5), 958-969 (2006)
PUBMED 16495487
REFERENCE 2 (bases 1 to 4648)
AUTHORS Stabach,P.R., Stankewich,M.C. and Morrow,J.S.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2000) Pathology, Yale University, 310 Cedar
Street, New Haven, CT 06520, USA
FEATURES Location/Qualifiers
source 1..4648
/db_xref="H-InvDB:HIT000075888"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/tissue_type="testis"
/note="longest alternatively spliced transcript; excludes
exons 12, 13, 19B and 21"
CDS 99..3638
/note="p137h; Sec31B; similar to yeast Sec31p; mammalian
COPII coat component; also found at plasma membrane;
contains WD repeats and proline-rich domains"
/codon_start=1
/product="secretory pathway component Sec31B-1"
/protein_id="AAF78243.1"
/translation="MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLE
IFEVDFRDPSLDLKHRGVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNV
THILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTL
GSKSQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSG
LAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELL
LTSAKDSQILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVM
GRSWEVQHMRQADKISSSFSKGQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSF
AFGGKLVTFGLPSTPAHLVPQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYC
QNKSQQALLQSEKMLWQFLKVTLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGE
SPQPKGNDLNSDRQQAFCSQASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGL
LSQALLLGELGPAVELCLKEERFADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLA
CVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEA
RLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMVLNRSLEQLRGPHGVSPGPAT
TYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPF
PRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGP
RTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSP
LPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGA
PCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPEL
QGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEALLQR
CSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGSFEQGLA
VHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV"
BASE COUNT 1061 a 1285 c 1207 g 1095 t
ORIGIN
1 gaggagcggc tccggccgcc gcgcctgacc cttgtccggg gtcttccgca cagtgggctg
61 agggccatgt cagttttctg ccacctacag gatagaccat gaagctgaag gaacttgagc
121 ggccagctgt ccaggcatgg agcccagcca gccaataccc tttgtatctg gccacaggaa
181 catctgccca acagctagat tcctccttca gcacaaatgg cacattggaa atatttgagg
241 ttgatttcag ggacccttct ctggacttga aacacagagg agtcctttct gccttgagca
301 ggtttcacaa gctggtctgg gggagctttg gcagtgggct tctggaaagc tccggggtta
361 ttgttggcgg cggggacaat ggcatgctta ttctatacaa tgtgacccac atcctgtctt
421 cggggaagga gcctgtgatt gctcagaaac agaagcacac gggggctgtc agagccctcg
481 acttgaatcc tttccagggc aacctcctgg cttcaggggc cagcgattct gaaatcttca
541 tttgggatct gaataacttg aatgtgccaa tgaccctggg atccaagtca cagcagcctc
601 cagaggacat caaggcactg tcttggaacc ggcaagccca acacattctg tcttctgctc
661 accccagtgg caaggcagtt gtgtgggatc tcaggaagaa tgaacctatc atcaaagtca
721 gtgatcacag caacaggatg cactgctcag gcctggcctg gcatcctgac atagccaccc
781 agttagtgct gtgctcagag gatgatcgac ttcccgtgat tcagctgtgg gacttgcgct
841 ttgcctcctc gcccttgaag gtgctggaga gccacagcag ggggatcttg tcagtgtcat
901 ggagccaggc tgatgctgag ctgctgctca ctagtgctaa ggacagccag atcttgtgcc
961 ggaacctggg gagcagtgag gtggtatata agctaccaac acagagcagc tggtgctttg
1021 atgtgcagtg gtgccctcgg gacccttcag tgttctctgc tgcctccttc aacggctgga
1081 tcagtttgta ctctgtgatg ggtaggagct gggaagtcca gcatatgaga caggctgaca
1141 agatctcctc ttccttcagc aaaggccagc ctctcccacc actgcaggtg ccagagcaag
1201 tggcacaagc accactgata cctcccctga aaaaaccccc caaatggatt agaagaccaa
1261 caggtgtttc atttgctttt ggagggaagc tggttacttt tggcctcccc agcacccctg
1321 cccatctggt gccacagcct tgcccccgcc tagtcttcat cagtcaagtc accacagaat
1381 ctgaattcct gatgcgatca gctgagctgc aggaggcctt gggatcagga aatctactga
1441 attactgtca gaacaagagc cagcaagctt tactgcaaag tgaaaagatg ctgtggcagt
1501 tcctgaaggt gaccttagag caagactcca gaatgaaatt cctaaagctt ttaggataca
1561 gtaaagatga gcttcagaag aaggtggcca catggttgaa gagtgacgtg gggctaggtg
1621 agagtcctca gcccaaggga aatgacctca acagtgacag acaacaggcc ttctgcagcc
1681 aggcctccaa acacaccaca aaggaagcct ctgcttcctc agccttcttt gatgagctgg
1741 tccctcagaa catgactcct tgggagatcc ccatcacaaa agatattgat ggactcctaa
1801 gccaggctct cctgcttggg gaactgggtc cggccgtgga gctgtgtctg aaggaggagc
1861 gctttgctga tgccattatc ctggcccagg ctgggggtac agatctgctg aagcaaacac
1921 aggagcgcta cttggccaag aagaaaacca aaatctcctc gcttctagcc tgtgttgtgc
1981 aaaagaattg gaaggatgtg gtgtgtacct gtagcctgaa gaactggaga gaggcactgg
2041 ctttgctact gacatactca ggcacagaga aatttcccga gctctgtgac atgctgggaa
2101 ctcgcatgga acaggagggc agcagggcac taacctccga agccagactc tgttatgtgt
2161 gctcagggag tgtggagcgg ctggtggagt gctgggcaaa atgccaccag gctttgtccc
2221 ccatggctct gcaggacctg atggagaagg tgatggttct taacaggagc ttggagcaac
2281 tgcggggtcc tcatggggtg agcccaggcc ctgccacaac ctacagggtc actcagtatg
2341 ccaacctcct ggcagcccag ggcagcctgg ccactgccat gagctttcta cccagggact
2401 gtgctcagcc accagttcag cagctaagag atcggctttt tcatgctcaa ggttctgctg
2461 tcttgggcca acagtctccc cctttcccct tcccccggat tgttgtggga gctaccctcc
2521 actctaaaga gacatcatct tacagattgg gatcccagcc ttctcaccag gtcccaactc
2581 catctccaag gccaagggtt ttcacccctc agtcatcacc agcgatgccc ttggcacctt
2641 cccatcctag cccttatcag ggtcccagga cacagaatat aagtgactac agggcacctg
2701 ggccccaggc catccagcct ttgcctttga gccctggggt aaggcctgct tcatctcagc
2761 cacagctatt aggagggcaa agggtgcaag ttcctaaccc ggtgggattc cctgggacat
2821 ggcctcttcc tggttcccct ctacccatgg catgcccagg catcatgcga cctggctcta
2881 cctccctgcc tgagactcct agactgttcc ctctgcttcc tctgagacca ctaggtcccg
2941 gccgcatggt ctcccacacc ccagcccctc ctgcaagctt ccctgtgcca taccttccag
3001 gggacccagg tgccccatgc tctagtgtcc tcccaaccac tggcatcttg actcctcacc
3061 caggacctca agattcctgg aaagaagccc cagcccccag gggaaacctc cagaggaaca
3121 agctgccaga gacatttatg cccccagcac caattactgc tccagttatg agcctcaccc
3181 ctgagctaca agggattctt ccctcacagc cccctgtctc cagtgtgagt catgctcccc
3241 caggagttcc aggagaactc agcctgcagc ttcagcacct gccacctgag aagatggaaa
3301 ggaaggagct gcccccagag catcagtcct tgaagagcag ctttgaggcg cttctccaac
3361 gctgctccct gtctgcaact gacttaaaga caaaaaggaa gctggaagag gcagcccagc
3421 gtctggagta tctatatgag aagctctgtg aggggacact ctcacctcat gtcgtggctg
3481 ggctccatga ggttgcccga tgtgtggatg caggaagctt tgagcagggc cttgcagtgc
3541 atgcccaggt ggcgggctgt agcagcttca gcgaggtgtc cagcttcatg cctatcctga
3601 aggctgtcct catcatcgct cataagctgc tggtctaaac caggcagcct ctcttgctag
3661 gaggccactt ctgctgttac ataactcctc cctgcagaag aggggacttc tgcaacagat
3721 tctgtttctt tttcccgact cttttccttg ctgccaggta tgtgatgctg taggcttggc
3781 tccaaaccag ctgagtgcct gctttttact cctttatgtc tggccttcta ggatctgtcc
3841 aagacactct caggcctgga ggcagggcat agaatcagtt cttcactctc cctaatacta
3901 cactctgtaa ggacctgggg caggatatct tctcccccag ggatcttcta tttaagtggc
3961 ttctgagagg gtgaacagga ttgttacttt taagcctacc tctgctgtga cccatcatgt
4021 gggtcttttg tttctccctt ctgtggttta tgagcctgcc cttacctttt ccctgcctct
4081 gacttggtat ttccaggtcc gtatttctct gtagcccagg gtctggggta gagctgactg
4141 ctgttcaccc tttgaacaac tcatggacgt gagggatggg tgctgagcag aaccaagaga
4201 ggaaactttg gcgctgttaa aatggaattt ctcatctgcc ggcattatta agggtgggct
4261 aggttggatg gaaggtgaaa gggatgaact gccttttgct ggaagctgtc ttaggctgtg
4321 agacaggagc aggggaacca cagcctatgg ggaactgccc ttgactccac ctatgttgga
4381 gccttagccc aaggccattc cttctgtgat gataaagccc agttctggaa ttggagccat
4441 attaaggaat gattctcttc cagcgctgct cctcaagggt tgggggtcct tctccctcgc
4501 agccaccaca tgtctcaggg ctaccttctc cgattggatt tgcatttgtg gcactgtctt
4561 tgatgcagtg atgtacttaa tggtgcaata aagctgcttc gatttgaaaa aaaaaaaaaa
4621 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//