LOCUS AF274049 3449 bp mRNA linear HUM 22-MAY-2002
DEFINITION Homo sapiens nuclear zinc finger protein Np97 (UHRF2) mRNA,
complete cds.
ACCESSION AF274049
VERSION AF274049.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3449)
AUTHORS Davenport,J.W., Fernandes,E.R., Neale,G.A.M. and Goorha,R.M.
TITLE LMO2-induced T cell leukemias overexpress a novel gene, Uhr1,
containing RING and PHD zinc fingers and an ubiquitin-like domain
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3449)
AUTHORS Davenport,J.W., Fernandes,E.R., Neale,G.A.M. and Goorha,R.M.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-2000) Virology and Molecular Biology, St. Jude
Children's Research Hospital, 332 N. Lauderdale Street, Memphis, TN
38105-2794, USA
FEATURES Location/Qualifiers
source 1..3449
/db_xref="H-InvDB:HIT000075880"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p24.1"
gene 1..3449
/gene="UHRF2"
CDS 169..2577
/gene="UHRF2"
/note="expressed throughout cell cycle, with maximum
expression during S-phase"
/codon_start=1
/product="nuclear zinc finger protein Np97"
/protein_id="AAM33799.1"
/translation="MWIQVRTIDGSKTCTIEDVSRKATIEELRERVWALFDVRPECQR
LFYRGKQLENGYTLFDYDVGLNDIIQLLVRPDPDHLPGTSTQIEAKPCSNSPPKVKKA
PRVGPSNQPSTSARARLIDPGFGIYKVNELVDARDVGLGAWFEAHIHSVTRASDGQSR
GKTPLKNGSSCKRTNGNIKHKSKENTNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPE
SGTLEMNVKDLRPRARTILKWNELNVGDVVMVNYNVESPGQRGFWFDAEITTLKTISR
TKKELRVKIFLGGSEGTLNDCKIISVDEIFKIERPGAHPLSFADGKFLRRNDPECDLC
GGDPEKKCHSCSCRVCGGKHEPNMQLLCDECNVAYHIYCLNPPLDKVPEEEYWYCPSC
KTDSSEVVKAGERLKMSKKKAKMPSASTESRRDWGRGMACVGRTRECTIVPSNHYGPI
PGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYT
GSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIR
SFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEG
IERSRRLCLRLQYPAGYPSDKEGKKPKGQSKKQPSGTTKRPISDDDCPSASKVYKASD
SAEAIEAFQLTPQQQHLIREDCQNQKLWDEVLSHLVEGPNFLKKLEQSFMCVCCQELV
YQPVTTECFHNVCKDCLQRSFKAQVFSCPACRHDLGQNYIMIPNEILQTLLDLFFPGY
SKGR"
misc_feature 169..390
/gene="UHRF2"
/note="Region: ubiquitin-like domain"
misc_feature 1147..1353
/gene="UHRF2"
/note="Region: PHD zinc finger"
misc_feature 1381..1410
/gene="UHRF2"
/note="Region: putative NLS"
misc_feature 2326..2574
/gene="UHRF2"
/note="Region: RING zinc finger"
BASE COUNT 984 a 669 c 830 g 966 t
ORIGIN
1 agagtcgtcg ccgcctgtcg ggcccggcgt ccggtcggtc cggtgggcgc gctcgcccgc
61 ctgccgctga gggcccgagc cgcagggaaa gcggcgcggg ccgggcgggg cgcggcgccc
121 agagctcagg gggagacaaa ggggaccggt tcctctctag gcgccaagat gtggatacag
181 gttcgcacca ttgatggctc caagacgtgc accattgagg acgtgtctcg caaagccacg
241 attgaggagc tgcgcgagcg ggtgtgggcg ctgttcgacg tgcggcccga atgccagcgc
301 ctcttctacc ggggcaagca gttggaaaat ggatatacct tatttgatta tgatgttgga
361 ctgaatgata taattcagct gctagttcgc ccagaccctg atcatcttcc tggcacatct
421 acacagattg aggctaaacc ctgttctaat agtccaccta aagtaaagaa agctccgagg
481 gtaggacctt ccaatcagcc atctacatca gctcgtgccc gtcttattga tcctggcttt
541 ggaatatata aggtaaatga attggtggat gccagagatg tcggccttgg tgcttggttt
601 gaagcacaca tacatagtgt tactagagct tctgatggac agtcacgtgg caaaactcca
661 ctgaagaatg gcagttcttg taaaaggact aatggaaata taaagcataa atccaaagag
721 aacacaaata aattggacag tgtaccctct acgtctaatt cagactgtgt tgctgctgat
781 gaagacgtta tttaccatat ccagtatgat gaatacccag aaagcggtac tctagaaatg
841 aatgtcaagg atcttagacc acgagctaga accattttga aatggaatga actaaatgtt
901 ggtgatgtgg taatggttaa ttataatgta gaaagtcctg gacaaagagg attctggttt
961 gatgcagaaa ttaccacatt gaagacaatc tcaaggacca aaaaagaact tcgtgtgaaa
1021 attttcctgg ggggttctga aggaacatta aatgactgca agataatatc tgtagatgaa
1081 atcttcaaga ttgagagacc tggagcccat cccctttcat ttgcagatgg aaagttttta
1141 aggcgaaatg accctgaatg tgacctgtgt ggtggagacc cagaaaagaa atgtcattct
1201 tgctcctgtc gtgtatgtgg tgggaaacat gaacccaaca tgcagcttct gtgtgatgaa
1261 tgtaatgtgg cttatcatat ttactgtctg aatccacctt tggataaagt cccagaagag
1321 gaatactggt attgtccttc ttgtaaaact gattccagtg aagttgtaaa ggctggtgaa
1381 agactcaaga tgagtaaaaa gaaagcaaag atgccgtcag ctagtactga aagccgaaga
1441 gactggggca ggggaatggc ttgtgttggt cgtacgagag aatgtactat tgtcccttct
1501 aatcattatg gacccattcc tggtattcct gttggatcaa cttggagatt tagagttcag
1561 gtgagcgaag caggtgttca cagaccccat gttggtggaa ttcatggtcg aagtaatgat
1621 ggggcttatt ctcttgtact ggctggtgga tttgcggatg aagtcgaccg aggtgatgag
1681 ttcacataca ctggaagcgg tggtaaaaat cttgctggta acaaaagaat tggtgcacct
1741 tcagctgatc aaacattaac aaacatgaac agggcattgg ccctaaactg tgatgctcca
1801 ttggatgata aaattggagc agagtctcgg aattggagag ctggtaagcc agtcagagtg
1861 atacgcagtt ttaaagggag gaagatcagc aaatatgctc ctgaagaagg caacagatat
1921 gatggcattt ataaggtggt gaaatactgg ccagagattt catcaagcca tggattcttg
1981 gtttggcgct atcttttaag aagagatgat gttgaacctg ctccttggac ctctgaagga
2041 atagaacggt caaggagatt atgtctacgt ttacagtatc cagcaggtta cccttcagat
2101 aaagaaggga agaagcctaa aggacagtca aagaagcagc ccagtggaac cacaaaaagg
2161 ccaatttcag atgatgactg tccaagtgcc tccaaagtgt acaaagcatc agattcagca
2221 gaagcaattg aggcttttca actaactcct caacagcaac atctcatcag agaagattgt
2281 caaaaccaga agctgtggga tgaagtgctt tcacatcttg tggaaggacc aaattttctg
2341 aaaaaattgg aacaatcttt tatgtgcgtt tgctgtcagg agctagttta ccagcctgtg
2401 acaactgagt gcttccacaa tgtctgtaaa gattgcctac agcgctcctt taaggcacag
2461 gttttctcct gccctgcttg ccggcatgat cttggccaga attacatcat gattcccaat
2521 gagattctgc agactctact tgaccttttc ttccctggct acagcaaagg acgatgatct
2581 gcctgctttc actgtgttgt tcatggtggc tttttggaca ataaagaatc taaaatgggt
2641 ggggagggtg gaagaaatgg tggactgtat ctctcacgtt ctgaagcagc taatcctctt
2701 tcccacatag ccatcatctt gtgtgtgtag taagaggccc atttctcaac tgtcttttaa
2761 atatctaaag gtagttcctg taacaactag ttttaatgag taaaaagtca aagcctcagc
2821 tctagttgat atccaagtta tgatttattt tgcaactacc tcaggacaga aaagatttat
2881 ggggatttta aaaatcattg aataactagt taaatgaaat tttagctaca cactgcctcc
2941 caaatattag ttgtgcctgg ttcttgtaat ttgattttac agaaaaggaa atgacacttg
3001 agatccttgg aatgaacaca gcttctaaag tgtgcatata cttttttaac gtctcttctt
3061 ccattacaat gtgtgttttg caaggacagg ttcatttttt ttagcccact ttgtgaactc
3121 cattgtgctt ttttctggtg ttttatgcaa gttgactact aatgactaat gagaacaata
3181 atgaatgcat tgttgctgca ttagtgtaat gtggtgtggt tttgcactta aaagaggtat
3241 tcatatgctc tagttgtaaa tgttcatgaa aatccacttc tctactagtc gaactgcttt
3301 tagtgtctca ccagtggttt tacatctgca gagttttgag ggctgtgctg acctttgaga
3361 ggatttgaaa ttgcttcata ttgtgatcct aaattttata ttcactatat tccctaaagt
3421 ataccttaat aaatatttta tgatcagaa
//