LOCUS AF272663 4193 bp mRNA linear HUM 04-JUL-2000
DEFINITION Homo sapiens gephyrin mRNA, complete cds.
ACCESSION AF272663
VERSION AF272663.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4193)
AUTHORS Schwarz,G., Gutzke,G., Kuper,J., Reiss,J. and Mendel,R.R.
TITLE Human gephyrin cDNA from brain tissue and exon borders
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4193)
AUTHORS Schwarz,G., Gutzke,G., Kuper,J., Reiss,J. and Mendel,R.R.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2000) Institute of Botany, Technical University
of Braunschweig, Humboldtstrasse 1, Braunschweig, Lower Saxony
38106, Germany
FEATURES Location/Qualifiers
source 1..4193
/db_xref="H-InvDB:HIT000075828"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
CDS 1122..3332
/function="role in molybdenum cofactor biosynthesis"
/function="role in glycin receptor anchoring"
/note="similar to Arabidopsis Cnx1, Drosophila cinnamon
and Escherichia coli Mog A, MoeA and Moa"
/codon_start=1
/product="gephyrin"
/protein_id="AAF81785.1"
/translation="MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQ
DPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKE
VIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILP
ALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEE
KKDSGVASTEDSSSSHITAAAIAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQAT
SRLSTASCPTPKVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVL
EMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGE
SQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQ
ARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGN
ELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRAD
VIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFAL
PGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHH
QEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL"
BASE COUNT 1078 a 1120 c 987 g 1008 t
ORIGIN
1 agcagcgctc atggcgaaga ggcttaaggc cacaaaaccg tgggacagca ggaggaagag
61 aagccaggta tctccactcc agctgccctg cctcagactc ctcagtttcg cacgtgagga
121 tcgtcttgca ggcactgact ggagatggaa tcctaaagca taggtgaagc ggaaatcctc
181 cttcagggag agcccactga ggaagccagc ggctagcacg aggcaggaca ggatacctcc
241 ctcttcgccc acggcggcct ctctgtcata gtagccaccg ttctgccact catgcagctt
301 tctaagacac ctctcggttc cccagcgctt tcagtggggc ggccggccac tcccgagggt
361 tgcaagagga ggcccggggt gctgagccag cctcgctgcc cccgcgtaga aagccggccc
421 gccggcgaga gccagcctaa ggcgcggaca accaacgagg tgtcaggctc ggcaggggat
481 tgcttctgtc tggggcccgg ccgaggttgc gttcgtgcct cgcgcgcaca cgctccgcgt
541 tcactcagcc aatccggtgc tactcgcgcg cccaggagcg atccgcggtc ctactcaggc
601 tgggccggct ccttcccgct cccaatactc agcacccgag ctctcactcc tcccctcact
661 ctccacgagt tccacgccta ggggtgtagc tccgcccttg tccccgagtc cgcccccgca
721 acctccagag cgtgtgctat cctttcctct cagtcctgcc atctagctgc cttgggtctc
781 gcgctccgca gagcgttccg acactctccg gcctcgttct gccgcctccg cgcgctctcc
841 ccgtgcggcc accgcgcccc ccaagcttgc ctccttcttg ccggacttgg ggccgcgcgc
901 cctgactcct tcccctcccg cggacccgcg cactcccggc gcggcctctc ccccacgcag
961 gccaccgtgc actctgtggc ctccccctcc ttccccgctc tcctcgcgct tctctggctc
1021 cctagctgtc gcgctctcct cggcgagcgc gctcccggcc cgcgcgctcc gggctccggt
1081 ttctcccggc tcctgtcagt gcggtgactg cgctgggaaa catggcgacc gagggaatga
1141 tccttactaa ccacgaccat caaatccgtg tcggagtcct tacagtgagt gatagttgct
1201 tcaggaatct tgcagaagac cgcagtggga taaatctcaa agatctcgta caagatcctt
1261 ctttgttggg tgggactata tcagcataca agatagtacc agatgaaata gaagaaatca
1321 aggaaaccct gatagattgg tgtgatgaaa aggaacttaa tttgatatta acaactggag
1381 gaacaggatt tgcaccacga gatgtcactc cagaggccac aaaagaagta atagaacggg
1441 aagcaccagg gatggccctg gcaatgctga tgggatcact taatgttaca cctctgggca
1501 tgctctctag gcctgtatgt ggaatcagag ggaaaacgct cataattaac ctgccaggta
1561 gcaagaaagg atctcaggaa tgctttcaat tcatactgcc agctctacct catgccattg
1621 accttttacg tgatgccatt gtaaaagtaa aggaggtgca tgatgaactt gaagatttgc
1681 cttccccacc tccccctctt tcccctcctc ctactaccag cccccataaa cagacagaag
1741 acaaaggagt tcaatgtgag gaagaggaag aagagaagaa agacagtggt gttgcttcaa
1801 cagaagatag ttcctcatca catataactg cagcagccat tgctgccaag attccagact
1861 ccatcatttc tcgtggtgtt caggtgctcc cacgagacac agcctccctc agcactactc
1921 cttcagaatc gcctcgtgct caggctacat ctcgcctctc tacagcttcc tgcccaacac
1981 caaaagtcca gtccaggtgc agcagcaagg agaacattct cagagccagt cacagtgctg
2041 tcgatatcac caaggtggct agaagacatc gcatgtctcc ttttcctctg acatctatgg
2101 acaaagcctt tatcacagtc ctggagatga ctccggtgct tgggacagaa atcatcaatt
2161 accgagatgg aatggggcga gtccttgctc aagatgtata tgcaaaagac aatttacccc
2221 ccttcccagc atcagtaaaa gatggctatg ctgtccgagc tgctgatggc ccaggagatc
2281 gtttcatcat tggggaatcc caagctggtg aacagccaac tcagacagta atgccaggac
2341 aagtcatgcg ggttacaaca ggtgctccaa taccctgcgg tgctgatgca gtagtacaag
2401 tggaagatac cgaacttatc agggaatcag atgatggcac tgaagaactt gaagtgcgaa
2461 ttctggtgca agctcggcca ggccaagata tcagacccat cggccatgac attaaaagag
2521 gggaatgtgt tttggccaaa ggaacccaca tgggcccctc agagattggt cttctggcaa
2581 ctgtaggtgt cacagaggtt gaagttaata agtttccagt ggttgcagtc atgtcaacag
2641 ggaatgagct gctaaatcct gaagatgacc tcttaccagg gaagattcga gacagcaatc
2701 gttcaactct tctagcaaca attcaggaac atggttaccc cacgatcaac ttgggtattg
2761 taggagacaa cccagatgac ttactcaatg ccttgaatga gggtatcagt cgtgctgatg
2821 tcatcatcac atcagggggt gtatccatgg gggaaaagga ctatctcaag caggtgctgg
2881 acattgatct tcatgctcag atccattttg gcagggtttt tatgaaacca ggcttgccaa
2941 caacatttgc aactttggat attgatggtg taagaaaaat aatctttgca ctacctggga
3001 atcctgtatc ggctgtggtc acctgcaatc tctttgttgt gcctgcactg aggaaaatgc
3061 agggcatctt ggatcctcgg ccaaccatca tcaaagcaag gttatcatgt gatgtaaaac
3121 ttgatcctcg tccagaatac catcggtgta tactaacttg gcatcaccaa gaaccactac
3181 cttgggcaca gagtacaggt aatcaaatga gcagccgtct gatgagcatg cgcagtgcca
3241 atggattgtt gatgctacct ccaaagacag aacagtacgt ggagctccac aaaggcgagg
3301 tggtggatgt catggtcatt ggacggctat gatggtcacc agcaggagaa agctttgatg
3361 catgtccaca tatcattgac tgtatcctgt aatatgcaac ggcacagcta gttttcccga
3421 tttggataaa agttgatctg tatagtcaac atcttgaact atatttcaaa tgaatttaaa
3481 tatcttttaa agaaaaaaac acctaaaaat aaatcttaac agaaaattct gttctgatta
3541 tatcaaggca aatttttcct ttcttgcaaa ttgctttgtg tgttcaatgc taggtctgat
3601 agcgatagct tttagtagac agcggtaggt gcctgcagaa cttgtgtttt tctcatcttt
3661 aaaatacaac tacttatgct cttaaatcaa ggctgtctgc ttatttatac tagcgtaggc
3721 aacacttgga tttcccttct tagtatgctt cataactgct ttacagagag cttttgcttg
3781 ttctttctca tgtatctcgt gtttatgtgc acagtgccaa aagaagactg actgggtgga
3841 ggctctgcct tgcctcaaga accatcccct gcagagcatc cagggaggtt tctcgcccca
3901 atagcctcac ggcacagtac tcttgggcag taactggaca ccttttattt gaagaaacaa
3961 actgaagaaa aaatgcttcc ttaagtgctg acagcctttt taaccaatac atttaaaatt
4021 gtacagaaca aaaaaataaa atcaaagact gatcttgtac agatattagt gttaccagca
4081 ttcatgtgga aatcaagagc aaagacaaaa taatgttaaa caattctgta ccataacatt
4141 ttctgtaatg atactgaaac ttaatgaata aaaaaattcc ttgatcatta ttt
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