LOCUS AF272151 2213 bp mRNA linear HUM 22-SEP-2000
DEFINITION Homo sapiens adaptor protein CIKS mRNA, complete cds.
ACCESSION AF272151
VERSION AF272151.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2213)
AUTHORS Leonardi,A., Chariot,A., Claudio,E., Cunningham,K. and
Siebenlist,U.
TITLE CIKS, a connection to Ikappa B kinase and stress-activated protein
kinase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 97 (19), 10494-10499 (2000)
PUBMED 10962033
REFERENCE 2 (bases 1 to 2213)
AUTHORS Leonardi,A., Chariot,A. and Siebenlist,U.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2000) Laboratory of Immunoregulation, NIAID,
Rockville Pike, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..2213
/db_xref="H-InvDB:HIT000075800"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
CDS 1..1725
/note="connects upstream signaling pathways to some IKK
and SAPK kinase modules"
/codon_start=1
/product="adaptor protein CIKS"
/protein_id="AAG15407.1"
/translation="MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPP
APNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSED
SFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPD
TGHDSDKSDQSLPNASADSLGGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGI
RQLERPLPLTSVCYPQDLPRPLRSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHC
PGSPDHQVPYGHDYPRAAYQQVIQPALPGQPLPGASVRGLHPVQKVILNYPSPWDQED
RPAQRDCSFPGLPRHQDQPHHQPPNRAGAPGESLECPAELRPQVPQPPSPAAVPRPPS
NPPARGTLKTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGI
DIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIK
QGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPL
PTLQVVPL"
BASE COUNT 573 a 620 c 516 g 504 t
ORIGIN
1 atgcctcctc agcttcaaga aactagaatg aaccgaagca ttcctgtgga ggttgatgaa
61 tcagaaccat acccaagtca gttgctgaaa ccaatcccag aatattcccc ggaagaggaa
121 tcagaaccac ctgctccaaa tataaggaac atggcaccca acagcttgtc tgcacccaca
181 atgcttcaca attcctccgg agacttttct caagctcact caaccctgaa acttgcaaat
241 caccagcggc ctgtatcccg gcaggtcacc tgcctgcgca ctcaagttct ggaggacagt
301 gaagacagtt tctgcaggag acacccaggc ctgggcaaag ctttcccttc tgggtgctct
361 gcagtcagcg agcctgcgtc tgagtctgtg gttggagccc tccctgcaga gcatcagttt
421 tcatttatgg aaaaacgtaa tcaatggctg gtatctcagc tttcagcggc ttctcctgac
481 actggccatg actcagacaa atcagaccaa agtttaccta atgcctcagc agactccttg
541 ggcggtagcc aggagatggt gcaacggccc cagcctcaca ggaaccgagc aggcctggat
601 ctgccaacca tagacacggg atatgattcc cagccccagg atgtcctggg catcaggcag
661 ctggaaaggc ccctgcccct cacctccgtg tgttaccccc aggacctccc cagacctctc
721 aggtccaggg agttccctca gtttgaacct cagaggtatc cagcatgtgc acagatgctg
781 cctcccaatc tttccccaca tgctccatgg aactatcatt accattgtcc tggaagtccc
841 gatcaccagg tgccatatgg ccatgactac cctcgagcag cctaccagca agtgatccag
901 ccggctctgc ctgggcagcc cctgcctgga gccagtgtga gaggcctgca ccctgtgcag
961 aaggttatcc tgaattatcc cagcccctgg gaccaagaag acaggcccgc acagagagac
1021 tgctcctttc cggggcttcc aaggcaccag gaccagccac atcaccagcc acctaataga
1081 gctggtgctc ctggggagtc cttggagtgc cctgcagagc tgagaccaca ggttccccag
1141 cctccgtccc cagctgctgt gcctagaccc cctagcaacc ctccagccag aggaactcta
1201 aaaacaagca atttgccaga agaattgcgg aaagtcttta tcacttattc gatggacaca
1261 gctatggagg tggtgaaatt cgtgaacttt ttgttggtaa atggcttcca aactgcaatt
1321 gacatatttg aggatagaat ccgaggcatt gatatcatta aatggatgga gcgctacctt
1381 agggataaga ccgtgatgat aatcgtagca atcagcccca aatacaaaca ggacgtggaa
1441 ggcgctgagt cgcagctgga cgaggatgag catggcttac atactaagta cattcatcga
1501 atgatgcaga ttgagttcat aaaacaagga agcatgaatt tcagattcat ccctgtgctc
1561 ttcccaaatg ctaagaagga gcatgtgccc acctggcttc agaacactca tgtctacagc
1621 tggcccaaga ataaaaaaaa catcctgctg cggctgctga gagaggaaga gtatgtggct
1681 cctccacggg ggcctctgcc cacccttcag gtggttccct tgtgacaccg ttcatcccca
1741 gatcactgag gccaggccat gtttggggcc ttgttctgac agcattctgg ctgaggcagg
1801 tcggtagcac tcctggctgg tttttttctg ttcctccccg agaggccctc tggcccccag
1861 gaaacctgtt gtgcagagct cttccccgga gacctccaca caccctggct ttgaagtgga
1921 gtctgtgact gctctgcatt ttctgctttt aaaaaaacca ttgcaggtgc cagtgtccca
1981 tatgttcctc ctgacagttt gatgtgtcca ttctgggcct ctcagtgctt agcaagtaga
2041 taatgtaagg gatgtggcag caaatggaaa tgactacaaa cactctccta tcaatcactt
2101 caggctactt ttatgagtag ccagatgctt gtgtatcctc agaccaaact gattcatgta
2161 caaataataa aatgtttact cttttgtgaa aaaaaaaaaa aaaaaaaaaa aaa
//