LOCUS AF264912 5810 bp mRNA linear HUM 14-MAY-2001
DEFINITION Homo sapiens tankyrase-like protein (TNKL) mRNA, complete cds.
ACCESSION AF264912
VERSION AF264912.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5810)
AUTHORS Kuimov,A.N., Kuprash,D.V., Petrov,V.N., Vdovichenko,K.K.,
Scanlan,M.J., Jongeneel,C.V., Lagarkova,M.A. and Nedospasov,S.A.
TITLE Cloning and characterization of TNKL, a member of tankyrase gene
family
JOURNAL Genes Immun. 2 (1), 52-55 (2001)
PUBMED 11294570
REFERENCE 2 (bases 1 to 5810)
AUTHORS Kuimov,A.N., Kuprash,D.V., Petrov,V.N., Vdovichenko,K.K.,
Kashkarova,U.A., Boitchenko,V.E., Nedospasov,S.A. and
Lagarkova,M.A.
TITLE Direct Submission
JOURNAL Submitted (08-MAY-2000) Laboratory of Molecular Immunology, A.N.
Belozersky Institute of Physico-Chemical Biology, Moscow State
University, Moscow 119899, Russia
FEATURES Location/Qualifiers
source 1..5810
/db_xref="H-InvDB:HIT000075535"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q22-10q24"
/tissue_type="breast carcinoma"
/note="derived from clones MO-BC-203 and I203"
gene <1..5810
/gene="TNKL"
/note="a new member of tankyrase gene family; current
Unigene claster Hs.168491"
CDS 1..3501
/gene="TNKL"
/note="a new member of tankyrase family"
/codon_start=1
/product="tankyrase-like protein"
/protein_id="AAG44694.1"
/translation="MSGRRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLV
TPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFG
HAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTA
LDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLA
AGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLW
QFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHS
LLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGAN
INEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCR
LLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETV
KKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNA
CSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD
GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTP
LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA
TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM
PPSALPSCYKPQVLNGVRSPGATADALSSGPSSPSSLSAASSLDNLSGSFSELSSVVS
SSGTEGASSLEKKEVPGVDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKE
IGINAYGHRHKLIKGVERLISGQQGLNPYLTLNTSGSGTILIDLSPDDKEFQSVEEEM
QSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLF
HGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRS
CYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQ
AYPEYLITYQIMRPEGMVDG"
STS complement(1132..1277)
/note="SHGC-53837"
STS complement(3665..3975)
/note="WI-16054"
STS complement(5544..5777)
/note="WI-8339"
BASE COUNT 1736 a 1094 c 1231 g 1749 t
ORIGIN
1 atgtcgggtc gccgctgcgc cggcggggga gcggcctgcg cgagcgccgc ggccgaggcc
61 gtggagccgg ccgcccgaga gctgttcgag gcgtgccgca acggggacgt ggaacgagtc
121 aagaggctgg tgacgcctga gaaggtgaac agccgcgaca cggcgggcag gaaatccacc
181 ccgctgcact tcgccgcagg ttttgggcgg aaagacgtag ttgaatattt gcttcagaat
241 ggtgcaaatg tccaagcacg tgatgatggg ggccttattc ctcttcataa tgcatgctct
301 tttggtcatg ctgaagtagt caatctcctt ttgcgacatg gtgcagaccc caatgctcga
361 gataattgga attatactcc tctccatgaa gctgcaatta aaggaaagat tgatgtttgc
421 attgtgctgt tacagcatgg agctgagcca accatccgaa atacagatgg aaggacagca
481 ttggatttag cagatccatc tgccaaagca gtgcttactg gtgaatataa gaaagatgaa
541 ctcttagaaa gtgccaggag tggcaatgaa gaaaaaatga tggctctact cacaccatta
601 aatgtcaact gccacgcaag tgatggcaga aagtcaactc cattacattt ggcagcagga
661 tataacagag taaagattgt acagctgtta ctgcaacatg gagctgatgt ccatgctaaa
721 gataaaggtg atctggtacc attacacaat gcctgttctt atggtcatta tgaagtaact
781 gaacttttgg tcaagcatgg tgcctgtgta aatgcaatgg acttgtggca attcactcct
841 cttcatgagg cagcttctaa gaacagggtt gaagtatgtt ctcttctctt aagttatggt
901 gcagacccaa cactgctcaa ttgtcacaat aaaagtgcta tagacttggc tcccacacca
961 cagttaaaag aaagattagc atatgaattt aaaggccact cgttgctgca agctgcacga
1021 gaagctgatg ttactcgaat caaaaaacat ctctctctgg aaatggtgaa tttcaagcat
1081 cctcaaacac atgaaacagc attgcattgt gctgctgcat ctccatatcc caaaagaaag
1141 caaatatgtg aactgttgct aagaaaagga gcaaacatca atgaaaagac taaagaattc
1201 ttgactcctc tgcacgtggc atctgagaaa gctcataatg atgttgttga agtagtggtg
1261 aaacatgaag caaaggttaa tgctctggat aatcttggtc agacttctct acacagagct
1321 gcatattgtg gtcatctaca aacctgccgc ctactcctga gctatgggtg tgatcctaac
1381 attatatccc ttcagggctt tactgcttta cagatgggaa atgaaaatgt acagcaactc
1441 ctccaagagg gtatctcatt aggtaattca gaggcagaca gacaattgct ggaagctgca
1501 aaggctggag atgtcgaaac tgtaaaaaaa ctgtgtactg ttcagagtgt caactgcaga
1561 gacattgaag ggcgtcagtc tacaccactt cattttgcag ctgggtataa cagagtgtcc
1621 gtggtggaat atctgctaca gcatggagct gatgtgcatg ctaaagataa aggaggcctt
1681 gtacctttgc acaatgcatg ttcttatgga cattatgaag ttgcagaact tcttgttaaa
1741 catggagcag tagttaatgt agctgattta tggaaattta cacctttaca tgaagcagca
1801 gcaaaaggaa aatatgaaat ttgcaaactt ctgctccagc atggtgcaga ccctacaaaa
1861 aaaaacaggg atggaaatac tcctttggat cttgttaaag atggagatac agatattcaa
1921 gatctgctta ggggagatgc agctttgcta gatgctgcca agaagggttg tttagccaga
1981 gtgaagaagt tgtcttctcc tgataatgta aattgccgcg atacccaagg cagacattca
2041 acacctttac atttagcagc tggttataat aatttagaag ttgcagagta tttgttacaa
2101 cacggagctg atgtgaatgc ccaagacaaa ggaggactta ttcctttaca taatgcagca
2161 tcttacgggc atgtagatgt agcagctcta ctaataaagt ataatgcatg tgtcaatgcc
2221 acggacaaat gggctttcac acctttgcac gaagcagccc aaaagggacg aacacagctt
2281 tgtgctttgt tgctagccca tggagctgac ccgactctta aaaatcagga aggacaaaca
2341 cctttagatt tagtttcagc agatgatgtc agcgctcttc tgacagcagc catgccccca
2401 tctgctctgc cctcttgtta caagcctcaa gtgctcaatg gtgtgagaag cccaggagcc
2461 actgcagatg ctctctcttc aggtccatct agcccatcaa gcctttctgc agccagcagt
2521 cttgacaact tatctgggag tttttcagaa ctgtcttcag tagttagttc aagtggaaca
2581 gagggtgctt ccagtttgga gaaaaaggag gttccaggag tagattttag cataactcaa
2641 ttcgtaagga atcttggact tgagcaccta atggatatat ttgagagaga acagatcact
2701 ttggatgtat tagttgagat ggggcacaag gagctgaagg agattggaat caatgcttat
2761 ggacataggc acaaactaat taaaggagtc gagagactta tctccggaca acaaggtctt
2821 aacccatatt taactttgaa cacctctggt agtggaacaa ttcttataga tctgtctcct
2881 gatgataaag agtttcagtc tgtggaggaa gagatgcaaa gtacagttcg agagcacaga
2941 gatggaggtc atgcaggtgg aatcttcaac agatacaata ttctcaagat tcagaaggtt
3001 tgtaacaaga aactatggga aagatacact caccggagaa aagaagtttc tgaagaaaac
3061 cacaaccatg ccaatgaacg aatgctattt catgggtctc cttttgtgaa tgcaattatc
3121 cacaaaggct ttgatgaaag gcatgcgtac ataggtggta tgtttggagc tggcatttat
3181 tttgctgaaa actcttccaa aagcaatcaa tatgtatatg gaattggagg aggtactggg
3241 tgtccagttc acaaagacag atcttgttac atttgccaca ggcagctgct cttttgccgg
3301 gtaaccttgg gaaagtcttt cctgcagttc agtgcaatga aaatggcaca ttctcctcca
3361 ggtcatcact cagtcactgg taggcccagt gtaaatggcc tagcattagc tgaatatgtt
3421 atttacagag gagaacaggc ttatcctgag tatttaatta cttaccagat tatgaggcct
3481 gaaggtatgg tcgatggata aatagttatt ttaagaaact aattccactg aacctaaaat
3541 catcaaagca gcagtggcct ctacgtttta ctcctttgct gaaaaaaaat catcttgccc
3601 acaggcctgt ggcaaaagga taaaaatgtg aacgaagttt aacattctga cttgataaag
3661 ctttaataat gtacagtgtt ttctaaatat ttcctgtttt ttcagcactt taacagatgc
3721 cattccaggt taaactgggt tgtctgtact aaattataaa cagagttaac ttgaaccttt
3781 tatatgttat gcattgattc taacaaactg taatgccctc aacagaacta attttactaa
3841 tacaatactg tgttctttaa aacacagcat ttacactgaa tacaatttca tttgtaaaac
3901 tgtaaataag agcttttgta ctagcccagt atttatttac attgctttgt aatataaatc
3961 tgttttagaa ctgcagcggt ttacaaaatt ttttcatatg tattgttcat ctatacttca
4021 tcttacatcg tcatgattga gtgatcttta catttgattc cagaggctat gttcagttgt
4081 tagttgggaa agattgagtt atcagattta atttgccgat gggagccttt atctgtcatt
4141 agaaatcttt ctcatttaag aacttatgaa tatgctgaag atttaatttg tgataccttt
4201 gtatgtatga gacacattcc aaagagctct aactatgata ggtcctgatt actaaagaag
4261 cttctttact ggcctcaatt tctagctttc atgttggaaa attttctgca gtccttctgt
4321 gaaaattaga gcaaagtgct cctgtttttt agagaaacta aatcttgctg ttgaacaatt
4381 attgtgttct tttcatggaa cataagtagg atgttaacat ttccagggtg ggaagggtaa
4441 tcctaaatca tttcccaatc tattctaatt accttaaatc taaaggggaa aaaaaaaatc
4501 acaaacagga ctgggtagtt ttttatccta agtatatttt ttcctgttct ttttacttgg
4561 ttttattgct gtatttatag ccaatctata catcatgggt aaacttaacc cagaactata
4621 aaatgtagtt gtttcagtcc ccttcaggcc tcctgaatgg gcaagtgcag tgaaacaggt
4681 gcttcctgct cctgggtttt ctctccatga tgttatgccc aattggaaat atgctgtcag
4741 tttgtgcacc atatggtgac cacgcctgtg ctcagtttgg cagctataga aggaaatgct
4801 gtcccataaa atgccatccc tatttctaat ataacactct tttccaggaa gcatgcttaa
4861 gcatcttgtt acagagacat acatccatta tggcttggca atctctttta tttgttgact
4921 ctagctccct tcaaagtcga ggaaagatct ttactcactt aatgaggaca ttccccatca
4981 ctgtctgtac cagttcacct ttattttacg ttttattcag tctgtaaatt aactggccct
5041 ttgcagtaac ttgtacataa agtgctagaa aatcatgttc cttgtcctga gtaagagtta
5101 atcagagtaa gtgcatttct ggagttgttt ctgtgatgta aattatgatc attatttaag
5161 aagtcaaatc ctgatcttga agtgcttttt atacagctct ctaataatta caaatatccg
5221 aaagtcattt cttggaacac aagtggagta tgccaaattt tatatgaatt tttcagatta
5281 tctaagcttc caggttttat aattagaaga taatgagaga attaatgggg tttatattta
5341 cattatctct caactatgta gcccatatta ctcaccctat gagtgaatct ggaattgctt
5401 ttcatgtgaa atcattgtgg tctatgagtt tacaatactg caaactgtgt tattttatct
5461 aaaccattgc ttaatgagtg tgtttttcca tgaatgaata taccgtggtt catatgttag
5521 catggcagca ttttcagata gctttttgtt tgttgggaag ttggggtttt ggggggaggg
5581 ggagtattag tacgttgcat ggaatagcct actttataat gatgggaatg ctttttcttt
5641 tgttttggga tttttttttt tgaagtgaaa tttaactttt tgtgccagta gtactattat
5701 acccatcttc agtgtcttac ttgtactgta tcaaattcca taccctcatt taattcttaa
5761 taaaactgtt cacttgtaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//