LOCUS AF264714 3262 bp mRNA linear HUM 18-JUN-2000
DEFINITION Homo sapiens vitiligo-associated protein VIT-1 (VIT1) mRNA,
complete cds.
ACCESSION AF264714
VERSION AF264714.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3262)
AUTHORS Le Poole,I.C., Stennett,L.S., Sarangarajan,R., Miki,T., Brown,T.L.
and Boissy,R.E.
TITLE VIT1, a Gene Downregulated in Vitiligo Melanocytes, may Regulate
Expression of a G/T Mismatch Repair Protein (Abstract #215)
JOURNAL (in) ? (Ed.);
61ST ANNUAL MEETING OF THE SOCIETY FOR INVESTIGATIVE DERMATOLOGY:
27;
(1999)
REFERENCE 2 (bases 1 to 3262)
AUTHORS Le Poole,I.C., Sarangarajan,R., Miki,T. and Boissy,R.E.
TITLE A Novel Gene Associated with Vitiligo (Abstract #OP5)
JOURNAL (in) ? (Ed.);
17TH MEETING OF THE INTERNATIONAL SOCIETY FOR PIGMENT CELL
RESEARCH: 215;
(2000)
REFERENCE 3 (bases 1 to 3262)
AUTHORS Le Poole,I.C., Sarangarajan,R., Miki,T., Brown,T.L., Stennett,L.S.
and Boissy,R.E.
TITLE VIT1, a gene associated with vitiligo
JOURNAL Unpublished
REFERENCE 4 (bases 1 to 3262)
AUTHORS Le Poole,I.C., Sarangarajan,R., Miki,T., Brown,T.L., Stennett,L.S.
and Boissy,R.E.
TITLE Direct Submission
JOURNAL Submitted (08-MAY-2000) Pathology, Loyola University Chicago, 2160
S. First Ave., Bldg. 112, Rm. 303, Maywood, IL 60153, USA
FEATURES Location/Qualifiers
source 1..3262
/db_xref="H-InvDB:HIT000075525"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16"
/cell_type="melanocyte"
gene 1..3262
/gene="VIT1"
/note="similar to MSH6"
CDS 1448..1873
/gene="VIT1"
/inference="non-experimental evidence, no additional
details recorded"
/note="similar to hypothetical protein DKFZp564K2364.1"
/codon_start=1
/product="vitiligo-associated protein VIT-1"
/protein_id="AAF76888.1"
/translation="MKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCN
TTDRNAICVNCIKKCHQGHDVEFIRHDRYVAHLLDILPNYFPPHFSNIWVSFCFRFFC
DCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN"
BASE COUNT 1121 a 547 c 635 g 959 t
ORIGIN
1 aggaaatggt ttctggaaaa cgttagtaag gtcagttttt aaacactgaa tccaaggttg
61 tcttctggaa tatccaaatt ggttatgacc agaatgtgat tcattatact aagctaaagg
121 aatagattaa agaattagca acagtggccg ggtgcagtgg ctcatgcctg taaccccagc
181 actttggggg aggcccaggt gggtggatca tttgaggtca ggagtttgag accagcctgg
241 ccaacatggt gaaacctaaa aatacaaaaa ttagccaggt gtggtggcag gtgcttgtaa
301 tcccagctgc ttgggaggct gaagcaggag aattgcttga acccggaggc aggggttgca
361 gtgagccaag atcacaccat tgcactccag cctgggtggc agagtgagac tctgtctcaa
421 aaattaaaaa gcaacagtgt atatgcaata gttgcaagat gtaagatcac ccaaagagta
481 tgcagaggga aatgagggac agaacccaga aatattaata cccagggagt gaacaggagg
541 aggaccccaa gaagttactg agtcagattt ttcccactca tccaggtgaa agtttaggtc
601 aataatgtga aataccagag ggattaaatg tctacagaaa taaaaccatg tctcacatta
661 agacaaacaa gtaggttgga gggatatttt gaaaggcaag gtgatattaa actttattct
721 gaaagtagtt tgttagagaa agaggcatga taagagttgc agttaactga ttggaaacta
781 tgcagcagat gaaactggaa taaaggaaac tcatcaggaa atgattatag taataagggc
841 cagaaataag ggcttgcttg cctgaactaa aaacaaagag gatacaaagg ttctagaaat
901 atttcaaagg aattagcttt aattcagcaa tactcattga gaatcaccta tgcacctggc
961 tctgaagatg aagtgctgag taaacttaga catggaccct gctatcatgg agatggcaga
1021 ttattggtca gaatgctctt acctgtcatt gtagcaattt tgttagatcc ttaatacctc
1081 tgaattgcta ataaacttgt tttggctgaa aaaatagtcc tgtgaatttt accatgcagt
1141 taaataagaa actaaaagca aacctaaata ccaccaaaaa ggttagtagt ctgttatatg
1201 cattagcctt aatctaagga aatattttat tataggtctc cttgaagaaa atgatatttt
1261 caggaatgct caagcaggtg ttctcatcag cactaatagt catccaatct taaggaaaaa
1321 cagaatattt gatggatttg ccgcaggtat tgaaattaca aatcacgcaa ctgcaacact
1381 agaaggcaat cagattttta acaaccggtt tggaggctta tttttagcat ctggtgttaa
1441 tgtgacaatg aaagataaca aaataatgaa caatcaagat gccatagaaa aggctgttag
1501 tagaggccaa tgtttatata aaatatcaag ttataccagc tatcccatgc atgatttcta
1561 cagatgtcat acttgtaaca ccacagatcg aaatgccata tgtgtgaact gcattaagaa
1621 gtgccatcag ggacatgatg tagagtttat tagacatgat aggtatgtag cacacttgct
1681 tgatatatta cccaattact ttccccctca cttttctaat atttgggttt cattttgctt
1741 taggtttttc tgtgactgtg gtgctggaac actgtctaat ccttgtacat tagctggtga
1801 gcctacacat gatacagata cactatatga ctctgctcca cctatagaat ctaatacatt
1861 gcagcacaac tgaattcctt ccctaaagaa aaagtcctgc cattgtaaca tcataactta
1921 aaacactttt ttggaagaag atttaaaata tttgcccatg ctacaggaag agactgtatt
1981 aaaaatggat acacaaggtc agttgacact atgaagctca agctaccaaa aagaaagtgg
2041 caatatattg actcaggatc tcaaagctgg gtgttttagc attactgtgt aaagacttga
2101 agggacagaa gtgaagaaaa taagctgcaa ttttgtacag ataccaactt ctgaaaagct
2161 ggtgttttta caactagcat tgaatgcagt ccaatttgca gtagtaatct tcaatagaca
2221 agcagctttg ttgctgcctt tatggacatg ggtaccaatt gcttttgtaa tatggtaaaa
2281 atgtgagcta gcacttctgc gttccttttg attttttttt tttaacatgt attcagattg
2341 agaaatatga ttttaatgcc ttaatctcat gtagtttgtt tttaatttca agcaaaatct
2401 tactgtactt gaatgtgccc tgttttgtta gcacacctag acttgctgta actgtactca
2461 tgtcccagta tgtacgttct ttctatgaaa gagaaaacac taatcttaaa ttatatccag
2521 caatgtttct ggtatccttt aagaaaagtt aagactatta tttccttccc ttccctgtgc
2581 agcattcaaa aatcacccct agaaaaagtg agtgttttaa tgagacttcc taggaaggga
2641 tgcactgtaa aacaaaagta ttcttgtaac tcagttttgt gaaaggtaaa aaactactat
2701 gttttaagta cactttagaa agtctcttca aaacaaacag tcctgtattt gaactctgtt
2761 catagttttt ttttgaacag tttagacaaa actgttggaa attaaaccaa tttcctgcat
2821 taagctgaga caagtatata aacagcccta tacagtttca tagcttttcc tcccccattt
2881 atgtgtattg gtgacagtgg gtataaaaca gcctgaaagt gtatgcatgt accataacat
2941 ttagacttaa tatattgtgg agtattcaat aaccattatg tagaaggtag ataagaatta
3001 aaagggttta atttcctaga aagaaaatgg aaaaatggtc atttttaaaa aataaagttt
3061 attagatcat aatgttgtct gaatttacca cctttgtcag aagtcaactc aaagcttcca
3121 atgtagtcag tctataattc cttaatcaaa gtcagcaatt tatggacagc ttcagcattt
3181 acagttgacc tttcactagc caggcaaact tcccttaaaa ttaaaaaaaa aaaaaaaaaa
3241 aaaaaaaaaa aaaaaaaaaa aa
//