LOCUS AF264014 4579 bp mRNA linear HUM 28-NOV-2000
DEFINITION Homo sapiens scavenger receptor cysteine-rich type 1 protein M160
precursor, mRNA, complete cds, alternatively spliced.
ACCESSION AF264014
VERSION AF264014.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4579)
AUTHORS Gronlund,J., Vitved,L., Lausen,M., Skjodt,K. and Holmskov,U.
TITLE Cloning of a novel scavenger receptor cysteine-rich type I
transmembrane molecule (M160) expressed by human macrophages
JOURNAL J. Immunol. 165 (11), 6406-6415 (2000)
PUBMED 11086079
REFERENCE 2 (bases 1 to 4579)
AUTHORS Groenlund,J., Vitved,L., Lausen,M., Skjodt,K. and Holmskov,U.
TITLE Direct Submission
JOURNAL Submitted (05-MAY-2000) Department of Immunology & Microbiology,
Institute of Medical Biology, University of Southern Denmark,
Odense University, Winsloewparken 21.1, Odense 5000, Denmark
FEATURES Location/Qualifiers
source 1..4579
/db_xref="H-InvDB:HIT000075512"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q13.3"
5'UTR 1..25
CDS 26..4387
/codon_start=1
/product="scavenger receptor cysteine-rich type 1 protein
M160 precursor"
/protein_id="AAF91396.1"
/translation="MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGT
DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQ
AVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDG
NNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIW
LDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVE
LKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGN
ESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSNNCSGRVEVRIHEQWWT
ICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTY
DGKAKRTCFRRSDAGVICSDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTR
NAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCV
HREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQL
DCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC
SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVS
REPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLV
GADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGL
TWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVE
INVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGN
ESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALIC
LEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVS
AHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLYSE
TETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGF
MWVDDIQCPKTHISIWQCLSAPWERRISSTAEETWITCEDRIRVRGGDTECSGRVEIW
HAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNES
FLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGRLALILSSIFGLLLPVLFIL
FLTWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGCED
ASDTSLLGVLPASEATK"
sig_peptide 26..151
misc_feature 152..469
/note="Region: scavenger receptor cysteine-rich domain
SRCR 1"
misc_feature 470..790
/note="Region: scavenger receptor cysteine-rich domain
SRCR 2"
misc_feature 791..1111
/note="Region: scavenger receptor cysteine-rich domain
SRCR 3"
misc_feature 1112..1432
/note="Region: scavenger receptor cysteine-rich domain
SRCR 4"
misc_feature 1433..1753
/note="Region: scavenger receptor cysteine-rich domain
SRCR 5"
misc_feature 1754..2074
/note="Region: scavenger receptor cysteine-rich domain
SRCR 6"
misc_feature 2075..2395
/note="Region: scavenger receptor cysteine-rich domain
SRCR 7"
misc_feature 2396..2710
/note="Region: scavenger receptor cysteine-rich domain
SRCR 8"
misc_feature 2711..3025
/note="Region: scavenger receptor cysteine-rich domain
SRCR 9"
misc_feature 3026..3118
/note="Region: interdomain segment"
misc_feature 3119..3433
/note="Region: scavenger receptor cysteine-rich domain
SRCR 10"
misc_feature 3434..3754
/note="Region: scavenger receptor cysteine-rich domain
SRCR 11"
misc_feature 3755..4063
/note="Region: scavenger receptor cysteine-rich domain
SRCR 12"
misc_feature 4064..4093
/note="Region: connecting peptide"
misc_feature 4094..4171
/note="Region: transmembrane domain"
misc_feature 4172..4384
/note="Region: cytoplasmatic domain"
3'UTR 4388..4579
regulatory 4456..4461
/regulatory_class="polyA_signal_sequence"
regulatory 4550..4555
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1147 a 919 c 1343 g 1170 t
ORIGIN
1 ggactcagga agagatagac ccataatgat gctgcctcaa aactcgtggc atattgattt
61 tggaagatgc tgctgtcatc agaacctttt ctctgctgtg gtaacttgca tcctgctcct
121 gaattcctgc tttctcatca gcagttttaa tggaacagat ttggagttga ggctggtcaa
181 tggagacggt ccctgctctg ggacagtgga ggtgaaattc cagggacagt gggggactgt
241 gtgtgatgat gggtggaaca ctactgcctc aactgtcgtg tgcaaacagc ttggatgtcc
301 attttccttc gccatgtttc gttttggaca agccgtgact agacatggaa aaatttggct
361 tgatgatgtt tcctgttatg gaaatgagtc agctctctgg gaatgtcaac accgggaatg
421 gggaagccat aactgttatc atggagaaga tgttggtgtg aactgttacg gtgaagccaa
481 tctgggtttg aggctagtgg atggaaacaa ctcctgttca gggagagtgg aggtgaaatt
541 ccaagaaagg tggggaacta tatgtgatga tgggtggaac ttgaatactg ctgccgtggt
601 gtgcaggcaa ctaggatgtc catcttcttt tatttcttct ggagttgtta atagccctgc
661 tgtattgcgc cccatttggc tggatgacat tttatgccag gggaatgagt tggcactctg
721 gaattgcaga catcgtggat ggggaaatca tgactgcagt cacaatgagg atgtcacatt
781 aacttgttat gatagtagtg atcttgaact aaggcttgta ggtggaacta accgctgtat
841 ggggagagta gagctgaaaa tccaaggaag gtgggggacc gtatgccacc ataagtggaa
901 caatgctgca gctgatgtcg tatgcaagca gttgggatgt ggaaccgcac ttcacttcgc
961 tggcttgcct catttgcagt cagggtctga tgttgtatgg cttgatggtg tctcctgctc
1021 cggtaatgaa tcttttcttt gggactgcag acattccgga accgtcaatt ttgactgtct
1081 tcatcaaaac gatgtgtctg tgatctgctc agatggagca gatttggaac tgcgactagc
1141 agatggaagt aacaattgtt cagggagagt agaggtgaga attcatgaac agtggtggac
1201 aatatgtgac cagaactgga agaatgaaca agcccttgtg gtttgtaagc agctaggatg
1261 tccgttcagc gtctttggca gtcgtcgtgc taaacctagt aatgaagcta gagacatttg
1321 gataaacagc atatcttgca ctgggaatga gtcagctctc tgggactgca catatgatgg
1381 aaaagcaaag cgaacatgct tccgaagatc agatgctgga gtaatttgtt ctgataaggc
1441 agatctggac ctaaggcttg tcggggctca tagcccctgt tatgggagat tggaggtgaa
1501 ataccaagga gagtggggga ctgtgtgtca tgacagatgg agcacaagga atgcagctgt
1561 tgtgtgtaaa caattgggat gtggaaagcc tatgcatgtg tttggtatga cctattttaa
1621 agaagcatca ggacctattt ggctggatga cgtttcttgc attggaaatg agtcaaatat
1681 ctgggactgt gaacacagtg gatggggaaa gcataattgt gtacacagag aggatgtgat
1741 tgtaacctgc tcaggtgatg caacatgggg cctgaggctg gtgggcggca gcaaccgctg
1801 ctcgggaaga ctggaggtgt actttcaagg acggtggggc acagtgtgtg atgacggctg
1861 gaacagtaaa gctgcagctg tggtgtgtag ccagctggac tgcccatctt ctatcattgg
1921 catgggtctg ggaaacgctt ctacaggata tggaaaaatt tggctcgatg atgtttcctg
1981 tgatggagat gagtcagatc tctggtcatg caggaacagt gggtggggaa ataatgactg
2041 cagtcacagt gaagatgttg gagtgatctg ttctgatgca tcggatatgg agctgaggct
2101 tgtgggtgga agcagcaggt gtgctggaaa agttgaggtg aatgtccagg gtgccgtggg
2161 aattctgtgt gctaatggct ggggaatgaa cattgctgaa gttgtttgca ggcaacttga
2221 atgtgggtct gcaatcaggg tctccagaga gcctcatttc acagaaagaa cattacacat
2281 cttaatgtcg aattctggct gcactggagg ggaagcctct ctctgggatt gtatacgatg
2341 ggagtggaaa cagactgcgt gtcatttaaa tatggaagca agtttgatct gctcagccca
2401 caggcagccc aggctggttg gagctgatat gccctgctct ggacgtgttg aagtgaaaca
2461 tgcagacaca tggcgctctg tctgtgattc tgatttctct cttcatgctg ccaatgtgct
2521 gtgcagagaa ttaaactgtg gagatgccat atctctttct gtgggagatc actttggaaa
2581 agggaatggt ctaacttggg ccgaaaagtt ccagtgtgaa gggagtgaaa ctcaccttgc
2641 attatgcccc attgttcaac atccggaaga cacttgtatc cacagcagag aagttggagt
2701 tgtctgttcc cgatatacag atgtccgact tgtgaatggc aaatcccagt gtgacgggca
2761 agtggagatc aacgtgcttg gacactgggg ctcactgtgt gacacccact gggacccaga
2821 agatgcccgt gttctatgca gacagctcag ctgtgggact gctctctcaa ccacaggagg
2881 aaaatatatt ggagaaagaa gtgttcgtgt gtggggacac aggtttcatt gcttagggaa
2941 tgagtcactt ctggataact gtcaaatgac agttcttgga gcacctccct gtatccatgg
3001 aaatactgtc tctgtgatct gcacaggaag cctgacccag ccactgtttc catgcctcgc
3061 aaatgtatct gacccatatt tgtctgcagt tccagagggc agtgctttga tctgcttaga
3121 ggacaaacgg ctccgcctag tggatgggga cagccgctgt gccgggagag tagagatcta
3181 tcacgacggc ttctggggca ccatctgtga tgacggctgg gacctgagcg atgcccacgt
3241 ggtgtgtcaa aagctgggct gtggagtggc cttcaatgcc acggtctctg ctcactttgg
3301 ggaggggtca gggcccatct ggctggatga cctgaactgc acaggaatgg agtcccactt
3361 gtggcagtgc ccttcccgcg gctgggggca gcacgactgc aggcacaagg aggacgcagg
3421 ggtcatctgc tcagaattca cagccttgag gctctacagt gaaactgaaa cagagagctg
3481 tgctgggaga ttggaagtct tctataacgg gacctggggc agcgtcggca ggaggaacat
3541 caccacagcc atagcaggca ttgtgtgcag gcagctgggc tgtggggaga atggagttgt
3601 cagcctcgcc cctttatcta agacaggctc tggtttcatg tgggtggatg acattcagtg
3661 tcctaaaacg catatctcca tatggcagtg cctgtctgcc ccatgggagc gaagaatctc
3721 cagcacagca gaagagacct ggatcacatg tgaagataga ataagagtgc gtggaggaga
3781 caccgagtgc tctgggagag tggagatctg gcacgcaggc tcctggggca cagtgtgtga
3841 tgactcctgg gacctggccg aggcggaagt ggtgtgtcag cagctgggct gtggctctgc
3901 tctggctgcc ctgagggacg cttcgtttgg ccagggaact ggaaccatct ggttggatga
3961 catgcggtgc aaaggaaatg agtcatttct atgggactgt cacgccaaac cctggggaca
4021 gagtgactgt ggacacaagg aagatgctgg cgtgaggtgc tctggacagt cgctgaaatc
4081 actgaatgcc tcctcaggtc gtttagcact tattttatcc agtatctttg ggctccttct
4141 cccggttctg tttattctat ttctcacgtg gtgccgagtt cagaaacaaa aacatctgcc
4201 cctcagagtt tcaaccagaa ggaggggttc tctcgaggag aatttattcc atgagatgga
4261 gacctgcctc aagagagagg acccacatgg gacaagaacc tcagatgaca cccccaacca
4321 tggttgtgaa gatgctagcg acacatcgct gttgggagtt cttcctgcct ctgaagccac
4381 aaaatgactt tagacttcca gggctcacca gatcaacctc taaatatctt tgaaggagac
4441 aacaactttt aaatgaataa agaggaagtc aagttgccct atggaaaact tgtccaaata
4501 acatttcttg aacaatagga gaacagctaa attgataaag actggtgata ataaaaattg
4561 aattatgtat atcactgtt
//