LOCUS AF261758 4248 bp mRNA linear HUM 10-OCT-2000
DEFINITION Homo sapiens seladin-1 mRNA, complete cds.
ACCESSION AF261758
VERSION AF261758.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4248)
AUTHORS Greeve,I., Hermans-Borgmeyer,I., Brellinger,C., Kasper,D.,
Gomez-Isla,T., Behl,C., Levkau,B. and Nitsch,R.M.
TITLE The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to
Alzheimer's disease-associated neurodegeneration and oxidative
stress
JOURNAL J. Neurosci. 20 (19), 7345-7352 (2000)
PUBMED 11007892
REFERENCE 2 (bases 1 to 4248)
AUTHORS Greeve,I.
TITLE Direct Submission
JOURNAL Submitted (28-APR-2000) Center for Molecular Neurobiology,
Martinistrasse 52, Hamburg 20246, Germany
FEATURES Location/Qualifiers
source 1..4248
/db_xref="H-InvDB:HIT000075303"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
CDS 100..1650
/codon_start=1
/product="seladin-1"
/protein_id="AAG17288.1"
/translation="MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSL
IFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSL
RVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELD
DLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSC
GTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDE
AVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRS
IFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMK
CLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEA
RSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYD
KICKAARH"
BASE COUNT 920 a 1171 c 1163 g 994 t
ORIGIN
1 cccgggctgt gggctacagg cgcagagcgg gccaggcgcg gagctggcgg cagtgacagg
61 aggcgcgaac ccgcagcgct taccgcgcgg cgccgcacca tggagcccgc cgtgtcgctg
121 gccgtgtgcg cgctgctctt cctgctgtgg gtgcgcctga aggggctgga gttcgtgctc
181 atccaccagc gctgggtgtt cgtgtgcctc ttcctcctgc cgctctcgct tatcttcgat
241 atctactact acgtgcgcgc ctgggtggtg ttcaagctca gcagcgctcc gcgcctgcac
301 gagcagcgcg tgcgggacat ccagaagcag gtgcgggaat ggaaggagca gggtagcaag
361 accttcatgt gcacggggcg ccctggctgg ctcactgtct cactacgtgt cgggaagtac
421 aagaagacac acaaaaacat catgatcaac ctgatggaca ttctggaagt ggacaccaag
481 aaacagattg tccgtgtgga gcccttggtg accatgggcc aggtgactgc cctgctgacc
541 tccattggct ggactctccc cgtgttgcct gagcttgatg acctcacagt ggggggcttg
601 atcatgggca caggcatcga gtcatcatcc cacaagtacg gcctgttcca acacatctgc
661 actgcttacg agctggtcct ggctgatggc agctttgtgc gatgcactcc gtccgaaaac
721 tcagacctgt tctatgccgt accctggtcc tgtgggacgc tgggtttcct ggtggccgct
781 gagatccgca tcatccctgc caagaagtac gtcaagctgc gtttcgagcc agtgcggggc
841 ctggaggcta tctgtgccaa gttcacccac gagtcccagc ggcaggagaa ccacttcgtg
901 gaagggctgc tctactccct ggatgaggct gtcattatga caggggtcat gacagatgag
961 gcagagccca gcaagctgaa tagcattggc aattactaca agccgtggtt ctttaagcat
1021 gtggagaact atctgaagac aaaccgagag ggcctggagt acattccctt gagacactac
1081 taccaccgcc acacgcgcag catcttctgg gagctccagg acatcatccc ctttggcaac
1141 aaccccatct tccgctacct ctttggctgg atggtgcctc ccaagatctc cctcctgaag
1201 ctgacccagg gtgagaccct gcgcaagctg tacgagcagc accacgtggt gcaggacatg
1261 ctggtgccca tgaagtgcct gcagcaggcc ctgcacacct tccaaaacga catccacgtc
1321 taccccatct ggctgtgtcc gttcatcctg cccagccagc caggcctagt gcaccccaaa
1381 ggaaatgagg cagagctcta catcgacatt ggagcatatg gggagccgcg tgtgaaacac
1441 tttgaagcca ggtcctgcat gaggcagctg gagaagtttg tccgcagcgt gcatggcttc
1501 cagatgctgt atgccgactg ctacatgaac cgggaggagt tctgggagat gtttgatggc
1561 tccttgtacc acaagctgcg agagaagctg ggttgccagg acgccttccc cgaggtgtac
1621 gacaagatct gcaaggccgc caggcactga gctggagccc gcctggagag acagacacgt
1681 gtgagtggtc aggcatcttc ccttcactca agcttggctg ctttcctaga tccacacttt
1741 caaagagaaa cccctccaga actcccaccc tgacagccca acaccacctt cctcctggct
1801 tccagggggc agcccagtgg aatggaaaga atgtgggatt tggagtcaga caagcctgag
1861 tccagttccc cgtttagaac tcattagctg tgtgactctg ggtgagtccc ttaacccctc
1921 tgagcccggg tctcttcatt agttgaaagg gatagtaata cctacttgca ggttgttgtc
1981 atctgagttg agcactggtc acattgaagg tgctgggtaa gtggtagctc ttgttgcttc
2041 ccgttcagcg tcacatctgc agtggagcct gaaaaggctc cacattaggt cacctgtgca
2101 cagccatggc tggaatgatg aaggggatac gctggagttg ccctgccatc gcctccatca
2161 gccagacgag gtcctcacag gagaaggaca gctcttcccc accctgggat ctcaggaggg
2221 cagccacgga gtggggaggc cccagatgcg ctgtgccaaa gccaggtccg aggccaaagt
2281 tctccctgcc atccttggtg ccgtcctgcc ccttcctcct tcatgcctgg gcctgcaggc
2341 ccaccccagc caccactgag tccactcgga gtgccctgtg ttcctggaga aggcattcca
2401 gggttgaatc ttgtcccagc ctcagcctgg gacacctagg tggagagagt ggtctccgct
2461 ctgaattgga tccaggggac ctgggctcat tcttcttggc tcaccaaccc tgcaggcctc
2521 atctttccca aaacccactt tgtcttggtg ggagtgggtc cgcgctgctc tgcagcaggg
2581 gctggggagt ggacagcatc aggtgggaaa gtggagtcca ccctcatgtt tctgtaggat
2641 tctcaccgtg gggctggaag aaaagagcat cgacttgatt tctccaacca ctcatccctc
2701 tttttctttc ttccaccact ccccacccca gctgtagtta atttcagtgc cttacaaatc
2761 ctaagctcag agaaagttcc atttccgttc cagagggaag ggaacctccc taggtccttc
2821 cctggcttgt tataacgcaa agcttggttg tttatgcaac tctatcttaa gaactgccca
2881 gcctcagctg aaaacccgaa tctgagaagg aattgcgtca tgtaagggaa gctggaatta
2941 agggagctga gccagtcatg gttgtggcgt gtgagtcagg agacctaggt ttcagcccct
3001 ctctactgtc agcgagctgt gcaacgtggg caagtcattg tcctctgagc tgcagtttcc
3061 tcatctgtca catcgctaca gacaagacct ccctggaacc cttctgattg tcttagacac
3121 tgtggttgca aaacccacgg aaagcctcat ttgtgtggaa agtcagagga aaaatgatcc
3181 agtggacact tggggattat ctgtcattca agatccttcc ttcaacccca aggccagctc
3241 ccatctcatt tccagaaagg ctcatacctg gcttgcaggg aagcatctgt cttgtcattc
3301 caggtgccag aatcctctca gagtcattga agggtgttca cccatcccac ccaaggcttg
3361 gcacactgcc agtgtcttag cagggtcttg tgagggctgg gggcatccag gcactcagaa
3421 ggcaaaggaa ccaccctacc catttggcct ctggaggggg cagaagaaag aaagaaacct
3481 catcctatat tttacaaagc atgtgaattc tggcattagc tctcatagga gacccatgtg
3541 cttccttgct cagtgcaaaa ctgatgattc tacttgctgt agatgaatgg ttaacacgag
3601 ctagttaaac agtgccattg ttttgccagt gaagcctcca accctaagcc actgggacgg
3661 tggccagaga tgccagcagc ctctgtcgcc cttagtcata taaccaaaat ccagacctta
3721 tccacaaccc ggggcttgga aaggaaggta ttttggaatc acaccctccg gttatgttgc
3781 tccagtaaaa tcttgcctgg aaagaggcag tcttcttagc atggtgagct gagttcatgg
3841 cttttttttg tagccagtcc tgtccctggc catccatgtg atggttttgg atggagttaa
3901 acttgatgcc agtgggcagt gcatgtggaa agtatcagag taagcctctc ccctccagag
3961 ccctgagttt cttggctgca tgaaggtttt ctttagaatc agaattgtag ccagtttctt
4021 tggccagaag gatgaatact tggatattac tgaaagggag gggtggagat gggtgtggca
4081 gtgtatggtg tgtgattttt attttcttct ttggtcatgg gggccaagga gaaaggcatg
4141 aatcttccct gtcaggctct tacagccaca ggcactgtgt ctactgtctg gaagacatgt
4201 ccccgtggct gtggggccgc tgcttctgtt taaataaaag tggcctgg
//