LOCUS AF257176 6816 bp mRNA linear HUM 02-MAY-2001
DEFINITION Homo sapiens kinesin superfamily protein KIF1B mRNA, complete cds.
ACCESSION AF257176
VERSION AF257176.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6816)
AUTHORS Yang,H.W., Takita,J., Chen,Y.Z., Soeda,E., Piao,H.Y., Hashizume,K.
and Hayashi,Y.
TITLE Cloning of human kif1b gene that maps at 1p36, which is
homozygously deleted in neuroblastoma cell line NB1 and mutated in
some other neuroblastoma cell lines
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6816)
AUTHORS Yang,H.W., Chen,Y.Z., Takita,J., Soeda,E., Piao,H.Y. and Hayashi,Y.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2000) Pediatrics, The University of Tokyo, Hongo
7-3-1, Bunkyo-Ku, Tokyo 113-8655, Japan
FEATURES Location/Qualifiers
source 1..6816
/db_xref="H-InvDB:HIT000075160"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36.2"
CDS 154..5466
/note="kinesin related protein"
/codon_start=1
/product="kinesin superfamily protein KIF1B"
/protein_id="AAK49332.1"
/translation="MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPK
EAPKSFSFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAG
KSYTMMGKQEESQAGIIPQLCEELFETNHDNCNEEMSYSVEVSYMEIYCERVRDLLNP
KNKGNLRVRDHPLRGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSH
VVYTIVFTQKKHDNETILATVKVSKTSLVDLAGSDRAASTGAKGTRLKEGAIINKSLT
TLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDE
TLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGS
LTSSPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLR
KTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDG
ITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRV
SQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQ
GIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETT
EEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKK
VQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVVAVEVQDLKNGATHYWSLEK
LKQRLDLMREMYDRAGEMASSAQDESETTVTGSDPFYDRFHWFKLVGSSPIFHGCVNE
RLADRTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFSDGH
DPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEE
APDYGSGIRQSGTAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEGQGQSSEVITP
PEEISRINDLDLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYA
DIFCQFNFLHRHDEAFSTEPLKNNGRGSPLAFYHVQNIAVEITESFVDYIKTKPIVFE
VFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQSMSKY
DLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHW
KDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYRFEAVWDSSLH
NSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSL
FGSGYSKSPDSNRVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWR
PRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSSGTLS
TSTSISSQISTTTFESAITPSESSGYDSGDIESLVDREKELATKCLQLLTHTFNREFS
QVHGSVSDCKLSDISPIGRDPSESSFSSATLTPSSTCPSLVDSRSNSLDQKTPEANSR
ASSPCPEFEQFQIVPAVETPYLARAGKNEFLNLVPDIEEIRPSSVVSKKGYLHFKEPL
YSNWAKHFVVVRRPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMVKTPNTFAVCT
KHRGVLLQALNDKDMNDWLYAFNPLLAGTIRSKLSRRCPSQSKY"
BASE COUNT 1800 a 1609 c 1708 g 1699 t
ORIGIN
1 cccggccccc cgcgcccccg cgcgccgcgg ctcctgttga cccggtccgc ccgtcggtct
61 gcagcgcggc tgaggaaact tggctgtaac ttcaaaagaa gatttgattc tttatttctg
121 gactgcatat atatatataa caaggccatt aaaatgtcgg gagcctcagt gaaggtggct
181 gtccgggtaa ggcccttcaa ttctcgagag accagcaagg aatccaaatg catcattcag
241 atgcaaggca actcgaccag tattattaac ccaaagaatc caaaggaagc tccaaagtcc
301 ttcagcttcg actattccta ctggtctcat acctcacccg aagatccctg ttttgcatct
361 cagaaccgtg tgtacaatga cattggcaag gaaatgctct tacacgcctt tgagggatat
421 aatgtctgta tttttgccta tgggcagact ggtgctggaa aatcttatac aatgatgggt
481 aaacaagaag aaagccaggc tggcatcatt ccacagttat gtgaagaact ttttgagaca
541 aatcatgaca actgtaatga agaaatgtcc tactctgtag aggtgagcta catggaaatt
601 tactgtgaaa gagtacgaga tttgctgaat ccaaaaaaca agggtaattt gcgtgtgcgt
661 gatcacccac ttcgtggacc ctatgtggag gatctttcca agttggcagt tacttcctac
721 acagacattg ctgacctcat ggatgctggg aacaaagcca ggacagtggc agctacaaac
781 atgaatgaaa caagtagccg ttcccacgtt gtgtatacga ttgtcttcac ccagaagaaa
841 cacgataatg agaccatcct tgccactgtg aaggttagta aaaccagctt ggtggatcta
901 gcaggaagtg accgagctgc ttcaactggt gccaaaggga ctcgcttaaa ggaaggagca
961 atcatcaata agtctcttac aactttgggc aaagtcattt cagccttggc cgaggtgagt
1021 aaaaagaaga agaaaacaga ttttattccc tacagggatt ctgtacttac ttggctcctt
1081 cgagaaaatt taggtggcaa ttctcggact gcaatggttg ctgctctgag ccccgcggat
1141 atcaactacg atgagacttt gagcactctg agatatgcag atcgtgcaaa acaaattaaa
1201 tgcaatgctg ttatcaatga ggaccccaat gccaaactgg ttcgtgaatt aaaggaggag
1261 gtgacacggc tgaaggacct tcttcgtgct cagggcctgg gagatattat tgatacatcc
1321 atggggtccc tcacttcatc cccatcttcc tgctcactca gtagtcaggt gggcttgacg
1381 tctgtgacca gtattcaaga gaggatcatg tctacacctg gaggagagga agctattgaa
1441 cgtttaaagg aatcagagaa gatcattgct gagttgaatg aaacttggga agagaagctt
1501 cgtaaaacag aggccatcag aatggagaga gaggctttgt tggctgagat gggagttgcc
1561 attcgggaag atggaggaac cctaggggtt ttctcaccta aaaagacccc acatcttgtt
1621 aacctcaatg aagacccact aatgtctgag tgcctacttt attacatcaa agatggaatt
1681 acaagggttg gccaagcaga tgctgagcgg cgccaggaca tagtgctgag cggggctcac
1741 attaaagaag agcattgtat cttccggagt gagagaagca acagcgggga agttatcgtg
1801 accttagagc cctgtgagcg ctcagaaacc tacgtaaatg gcaagagggt gtcccagcct
1861 gttcagctgc gctcaggaaa ccgtatcatc atgggtaaaa accatgtttt ccgctttaac
1921 cacccggaac aagcacgagc tgagcgagag aagactcctt ctgctgagac cccctctgag
1981 cctgtggact ggacatttgc ccagagggag cttctggaaa aacaaggaat tgatatgaaa
2041 caagagatgg agaaaaggct acaggaaatg gagatcttat acaaaaagga gaaggaagaa
2101 gcagatcttc ttttggagca gcagagactg gactatgaga gtaaattgca ggccttgcag
2161 aagcaggttg aaacccgatc tctggctgca gaaacaactg aagaggagga agaagaggaa
2221 gaagttcctt ggacacagca tgaatttgag ttggcccaat gggccttccg gaaatggaag
2281 tctcatcagt ttacttcatt acgggactta ctctggggca atgccgtgta cctaaaggag
2341 gccaatgcca tcagtgtgga actgaaaaag aaggtgcagt ttcagtttgt tctgctgact
2401 gacacactgt actccccttt gcctcctgaa ttacttccca ctgagatgga aaaaactcat
2461 gaggacaggc ctttccctcg cacagtggta gcagtagaag tccaggattt gaagaatgga
2521 gcaacacact attggtcttt ggagaaactc aagcagaggc tggatttgat gcgagagatg
2581 tatgataggg caggggagat ggcctccagt gcccaagacg aaagcgaaac cactgtgact
2641 ggcagcgatc ccttctatga tcggttccac tggttcaaac ttgtggggag ctcccccatt
2701 ttccacggct gtgtgaacga gcgccttgcc gaccgcacac cctcccccac tttttccacg
2761 gccgattccg acatcactga gctggctgac gagcagcaag atgagatgga ggattttgat
2821 gatgaggcat tcgtggatga cgccggctct gacgcaggga cggaggaggg atcagatctc
2881 ttcagtgacg ggcatgaccc gttttacgac cgatcccctt ggttcatttt agtgggaagg
2941 gcatttgttt acctgagcaa tctgctgtat cccgtgcccc tgatccacag ggtggccatc
3001 gtcagtgaga aaggtgaagt gcggggattt ctgcgtgtgg ctgtacaggc catcgcagcg
3061 gatgaagaag ctcctgatta tggctctgga attcgacagt caggaacagc taaaatatct
3121 tttgataatg aatactttaa tcagagtgac ttttcgtctg ttgcaatgac tcgttctggt
3181 ctgtccttgg aggagttgag gattgtggaa ggacagggtc agagttctga ggtcatcact
3241 cctccagaag aaatcagtcg aattaatgac ttggatttga agtcaagcac tttgctggat
3301 ggtaagatgg taatggaagg gttttctgaa gagattggca accacctgaa actgggcagt
3361 gccttcactt tccgagtaac agtgttgcag gccagtggaa tcctcccaga gtatgcagat
3421 atcttctgtc agttcaactt tttgcatcgc catgatgaag cattctccac ggagcccctc
3481 aaaaacaatg gcagaggaag tcccctggcc ttttatcatg tgcagaatat tgcagtggag
3541 atcactgaat catttgtgga ttacatcaaa accaagccta ttgtatttga agtctttggg
3601 cattatcagc agcacccact tcatctgcaa ggacaggagc ttaacagtcc gcctcagccg
3661 tgccgccgat tcttccctcc acccatgcca ctgtccaagc cagttccagc caccaagtta
3721 aacacgatga gcaaaaccag ccttggccag agcatgagca agtatgacct cctggtttgg
3781 tttgagatca gtgaactgga gcctacagga gagtatatcc cagctgtggt tgaccacaca
3841 gcaggcttgc cttgccaggg gacatttttg cttcatcagg gcatccagcg aaggatcaca
3901 gtgaccatta tccatgagaa ggggagcgag ctccattgga aagatgttcg tgaactggtg
3961 gtaggtcgta ttcggaataa gcctgaggtg gatgaagctg cagttgatgc catcctctcc
4021 ctaaatatta tttctgccaa gtacctgaag tcttcccaca actctagcag gaccttctac
4081 cgctttgagg ctgtgtggga tagctctctg cataactccc ttcttctgaa ccgagtgaca
4141 ccctatggag aaaagatcta catgaccttg tcggcctacc tagagctgga tcattgcatc
4201 cagccggctg tcatcaccaa ggatgtgtgc atggtcttct actcccgaga tgccaagatc
4261 tcaccaccac gctctctgcg tagcctcttt ggcagcggct actcaaagtc accagattcg
4321 aatcgagtca ctggcattta cgaactcagc ttatgcaaaa tgtcagacac aggtagtcca
4381 ggtatgcaga gaaggagaag aaaaatctta gatacgtcag tggcatatgt gcggggagaa
4441 gagaacttag caggctggcg gccccgtgga gacagcctca tccttgagca ccagtgggag
4501 ctggagaagc tggagctcct acatgaggtg gaaaaaaccc gccacttttt gctgctgcgt
4561 gagagacttg gtgacagcat ccccaaatcc ctgagcgact cgttatcccc cagcctcagc
4621 agtgggaccc tcagcacctc caccagtatc tcctctcaga tctcaaccac tacctttgaa
4681 agcgccatca cacctagcga gagcagtggc tatgattcag gagacatcga aagcctggtg
4741 gaccgagaga aagagctggc taccaagtgc ctgcaacttc tcacccacac tttcaacaga
4801 gaattcagcc aggtgcacgg cagcgtcagt gactgtaagt tgtctgatat ctctccaatt
4861 ggacgggatc cctctgagtc cagtttcagc agtgccaccc tcactccctc ctccacctgt
4921 ccctctctgg tagactctag gagcaactct ctggatcaga agaccccaga agccaattcc
4981 cgggcctcta gtccctgccc agaatttgaa cagtttcaga ttgtcccagc tgtggaaaca
5041 ccatatttgg cccgagcagg aaaaaacgaa tttctcaatc ttgttccaga tattgaagaa
5101 attagaccaa gctcagtggt ctctaagaaa ggataccttc atttcaagga gcctctttac
5161 agtaactggg ctaaacattt tgttgtcgtc cgtcggcctt atgtcttcat ctataacagt
5221 gacaaagacc ctgtggagcg tggaatcatt aacctgtcca cagcacaggt ggagtacagt
5281 gaggaccagc aggccatggt gaagacacca aacacctttg ctgtctgcac aaagcaccgt
5341 ggggtccttt tgcaggccct caatgacaaa gacatgaacg actggttgta tgccttcaac
5401 ccacttctag ctggcacaat acggtcaaag ctttcccgca gatgcccgag ccagtcgaaa
5461 tactaagtga ctctgccgag tgccctcact cgccttcgag agataaagaa agcgttacct
5521 ctcatttctc tttgtgattc ttgacggtga ctcttgtatg taatcctgtg gcttaactac
5581 ttctccctcc ttgtccagca cttttctagc tctcccgttc cccatctcca ttgctctgta
5641 ctcttttctt ttttcttgtg ctgagaatct cgttagtagc atgtggccta acaaaaggaa
5701 aaaatgtttt taaacacaca cacacacaca cacacacaca cacacataca cagacaaaaa
5761 cacaaaaact ctgaggggat ctggtgaatc tccaaattat tgtgggtgta ctttggcttc
5821 cttttgtatg ataggtcccc atcatgacca cctctgatgt ctgtgctgct gtcaccaggc
5881 acctttgttt ttcaagacaa catacttttt ttttcttttc tctgtttgtg atatcacttt
5941 aatttttctt gggtggctta gagactaagg gaggagacat ctggcctttt tagaacctga
6001 gaggaaaaaa agagtctttt tttcccctct gtctcttttt gccatggcta atccctgcat
6061 ttccattcag ggaaaaggtg gtagtgagca tagaactgca acagttatat tctgagtcaa
6121 agttggggct ttttacggca taattatgga atttttattt actggtagag aggagacgag
6181 aggctttttc agtgggcctg ggacagtggc tgctcttgac tttgtgtgaa gggaaatgcc
6241 aaggatgctt ctggtggact tcaggggacc ccagggtttg gccgtgggcc gtgatggcag
6301 caggcggtgg gatgcttgta gctcctcaca gcaggattcc tgcccactgt tttttctctg
6361 ttgggaggga agctcttttc taggagtgtc tcagttctgc ttttggcatt agtgatggtg
6421 gtggtacagt tggaattagt gccatgtcat acacaaatgt tccacaaggc gggagtgttt
6481 cactttctgg tgataaactt gatggtcatt gttatgatta agataatgcc gggcaggccg
6541 ggcacagtgg ctcacgcctg taatccaagc acttggggag gccgaggcgg gcagatcacg
6601 agatcaggag ttcaagacca gcctggccaa tgtgatgaaa ccccgtctct actaaaaata
6661 caaaattagt cgggtatggt ggcacatgcc tgtaattcca gctgcttggg agcctgaggc
6721 aggagaactg cttgaaccca ggaggcagag gttgcagtga gccaagatcg cgctattgca
6781 ctccagcctg ggtgacagag caagactctg cctcag
//