LOCUS AF256223 2404 bp mRNA linear HUM 02-MAY-2000
DEFINITION Homo sapiens ets family transcription factor ELF2B (ELF2) mRNA,
complete cds, alternatively spliced.
ACCESSION AF256223
VERSION AF256223.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2404)
AUTHORS Wilkinson,D.A., Neale,G.A., Mao,S., Naeve,C.W. and Goorha,R.M.
TITLE Elf-2, a rhombotin-2 binding ets transcription factor: discovery
and potential role in T cell leukemia
JOURNAL Leukemia 11 (1), 86-96 (1997)
PUBMED 9001422
REFERENCE 2 (bases 1 to 2404)
AUTHORS Wilkinson,D.A., Neale,G.A.M., Mao,S., Fernandes,E.R.,
Davenport,J.W., Naeve,C.W. and Goorha,R.M.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2000) Virology and Molecular Biology, St. Jude
Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38120,
USA
FEATURES Location/Qualifiers
source 1..2404
/db_xref="H-InvDB:HIT000075151"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="K562"
gene 1..2404
/gene="ELF2"
CDS 114..1679
/gene="ELF2"
/note="alternatively spliced; lacks N-terminal
transactivation domain"
/codon_start=1
/product="ets family transcription factor ELF2B"
/protein_id="AAF67196.1"
/translation="MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLH
MESPTCLRDSRSPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMKKK
KVGRKPKTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQ
REKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFK
DMPKNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPINC
SRAEKGVARVVNITSPGHDASSRSPTTTASVSATAAPRTVRVAMQVPVVMTSLGQKIS
TVAVQSVNAGAPLITSTSPTTATSPKVVIQTIPTVMPASTENGDKITMQPAKIITIPA
TQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSMPTQQASGQTP
PRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVEEKPADGNKTVTHVVVVSAPSAIALP
VTMKTEGLVTCEK"
misc_feature 639..764
/gene="ELF2"
/note="ets domain; DNA binding site"
misc_feature 1203..1469
/gene="ELF2"
/note="LMO2-binding site; DNA binding site"
BASE COUNT 807 a 493 c 509 g 595 t
ORIGIN
1 tgtgtgtcgg tcgcacggcg tgtgtctccg gccgcgggtt ccgcctcctc ccctgccgcc
61 gctgctcacg gtgtaagtca atgtgaagca gcagctccag ccccgggata aacatggcga
121 cgtctctgca tgagggaccc acgaaccagc tggatctgct catccgggcc gtggaagcat
181 cagttcacag cagtaatgca cactgtacag ataagacaat tgaagctgct gaagccctgc
241 ttcatatgga atctcctacc tgcttgaggg attcaagaag tcctgaattc atccatgctg
301 ctatgaggcc agatgtcatt acagaaactg tagtggaggt gtcaactgaa gagtctgaac
361 ccatggatac ctctcctatt ccaacatcac cagatagcca tgaaccaatg aaaaagaaaa
421 aagttggccg taaaccaaag acccagcaat caccaatttc caatgggtct cctgagttag
481 gtataaagaa gaaaccaaga gaaggaaaag gaaacacaac ctatttgtgg gagtttcttt
541 tagatctact tcaagataaa aatacttgtc ccaggtatat taaatggact cagagagaaa
601 aaggcatatt caagctggtg gattcaaagg ctgtctctaa gctttgggga aagcataaga
661 acaaaccaga catgaactat gaaaccatgg gacgagcttt gagatactac taccaaaggg
721 gaattcttgc aaaggttgaa ggacagaggc ttgtatatca gttcaaggat atgccgaaaa
781 acatagtggt catagatgat gacaaaagtg aaacctgtaa tgaagattta gcaggaacta
841 ctgatgaaaa atcattagaa cgagtgtcac tgtctgcaga aagtctcctg aaagcagcat
901 cctctgttcg cagtggaaaa aattcatccc ctataaactg ctccagagca gagaagggtg
961 tagctagagt tgtgaatatc acttcccctg ggcacgatgc ttcatccagg tctcctacta
1021 ccactgcatc tgtgtcagca acagcagctc caaggacagt tcgtgtggca atgcaggtac
1081 ctgttgtaat gacatcattg ggtcagaaaa tttcaactgt ggcagttcag tcagttaatg
1141 caggtgcacc attaataacc agcactagtc caacaacagc gacctctcca aaggtagtca
1201 ttcagacaat ccctactgtg atgccagctt ctactgaaaa tggagacaaa atcaccatgc
1261 agcctgccaa aattattacc atcccagcta cacagcttgc acagtgtcaa ctgcagacaa
1321 agtcaaatct gactggatca ggaagcatta acattgttgg aaccccattg gctgtgagag
1381 cacttacccc tgtttcaata gcccatggta cacctgtaat gagactatca atgcctactc
1441 agcaggcatc tggccagact cctcctcgag ttatcagtgc agtcataaag gggccagagg
1501 ttaaatcgga agcagtggca aaaaagcaag aacatgatgt gaaaactttg cagctagtag
1561 aagaaaaacc agcagatgga aataagacag tgacccacgt agtggttgtc agtgcgcctt
1621 cagctattgc ccttcctgta actatgaaaa cagaaggact agtgacatgt gagaaataaa
1681 atagcagctc caccatggac ttcaggctgt tagtggcagt actgacataa acatttgcaa
1741 gggaagtcat caagaaaagt caaagaagac tttaaaacat ttttaatgca tatacaaaaa
1801 caatcagact tactggaaat aaattaccta tcccatgttt cagtgggaaa tgaactacat
1861 attgagatgc tgacagaaaa ctgcctctta cagtaggaaa caactgaacc catcaataag
1921 aaaaaggatc gaaagggacc aagcagctca ctacgatatc aagttacact aagacttgga
1981 acactaacat tctgtaagag gttatatagt tttcagtggg aggggttggg atgggtaatc
2041 tcattgttac atatagcaat ttttgatgca ttttatatgc ataccagcaa ttattactgt
2101 gttcgcacag ttctcactta actggtgcta tgtgaagact ctgctaatat aggtatttta
2161 gaatgtgaat tgaagaatgg atcccaaaaa cttcagaaag aggatagcaa aaaaagatct
2221 agtgcgattt tatatatata tatatatata tatacataca tatatatata tcatatagct
2281 taagctgatt taaaacaaag gccttagact aattttcgat tttctttctt gaaataagct
2341 aatggcttgt ttgtgtaaag cttttttatt aaaagaaaaa ttttaaaaaa aaaaaaaaaa
2401 aaaa
//