LOCUS AF256222 2653 bp mRNA linear HUM 02-MAY-2000
DEFINITION Homo sapiens ets family transcription factor ELF2A (ELF2) mRNA,
complete cds, alternatively spliced.
ACCESSION AF256222
VERSION AF256222.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2653)
AUTHORS Wilkinson,D.A., Neale,G.A., Mao,S., Naeve,C.W. and Goorha,R.M.
TITLE Elf-2, a rhombotin-2 binding ets transcription factor: discovery
and potential role in T cell leukemia
JOURNAL Leukemia 11 (1), 86-96 (1997)
PUBMED 9001422
REFERENCE 2 (bases 1 to 2653)
AUTHORS Wilkinson,D.A., Neale,G.A.M., Mao,S., Fernandes,E.R.,
Davenport,J.W., Naeve,C.W. and Goorha,R.M.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2000) Virology and Molecular Biology, St. Jude
Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38120,
USA
FEATURES Location/Qualifiers
source 1..2653
/db_xref="H-InvDB:HIT000075150"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="K562"
gene 1..2653
/gene="ELF2"
CDS 183..1928
/gene="ELF2"
/note="alternatively spliced; includes N-terminal
transactivation domain"
/codon_start=1
/product="ets family transcription factor ELF2A"
/protein_id="AAF67195.1"
/translation="MTSAVVDSGGTILELSSNGVENQEESEKVSEYPAVIVEPVPSAR
LEQGYAAQVLVYDDETYMMQDVAEEQEVETENVETVEASVHSSNAHCTDKTIEAAEAL
LHMESPTCLRDSRSPEFIHAAMRPDVITETVVEVSTEESEPMDTSPIPTSPDSHEPMK
KKKVGRKPKTQQSPISNGSPELGIKKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKW
TQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ
FKDMPKNIVVIDDDKSETCNEDLAGTTDEKSLERVSLSAESLLKAASSVRSGKNSSPI
NCSRAEKGVARVVNITSPGHDASSRSPTTTASVSATAAPRTVRVAMQVPVVMTSLGQK
ISTVAVQSVNAGAPLITSTSPTTATSPKVVIQTIPTVMPASTENGDKITMQPAKIITI
PATQLAQCQLQTKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSMPTQQASGQ
TPPRVISAVIKGPEVKSEAVAKKQEHDVKTLQLVEEKPADGNKTVTHVVVVSAPSAIA
LPVTMKTEGLVTCEK"
misc_feature 888..1016
/gene="ELF2"
/note="ets domain; DNA binding site"
misc_feature 1452..1718
/gene="ELF2"
/note="LMO2-binding site; DNA binding site"
BASE COUNT 917 a 507 c 551 g 678 t
ORIGIN
1 acttaacata caaactgctt tctggttaat catctttaga agactggatt tctggatatc
61 tactccactc catctctatt gacttttaaa acatgataat gcaaacctat aacactggca
121 accatcagtg aacctttaat ttcattgatt aatagcgttt gaagcttcct cagggaataa
181 caatgacatc agcagtggtt gacagtggag gtactatttt ggagctttcc agcaatggag
241 tagaaaatca agaggaaagt gaaaaggttt ctgaatatcc agcagtgatt gtggagccag
301 ttccaagtgc cagattagag cagggctatg cagcccaggt tctggtttat gatgatgaga
361 cttatatgat gcaagatgtg gcagaagaac aagaagttga gaccgagaat gtggaaacag
421 tggaagcatc agttcacagc agtaatgcac actgtacaga taagacaatt gaagctgctg
481 aagccctgct tcatatggaa tctcctacct gcttgaggga ttcaagaagt cctgaattca
541 tccatgctgc tatgaggcca gatgtcatta cagaaactgt agtggaggtg tcaactgaag
601 agtctgaacc catggatacc tctcctattc caacatcacc agatagccat gaaccaatga
661 aaaagaaaaa agttggccgt aaaccaaaga cccagcaatc accaatttcc aatgggtctc
721 ctgagttagg tataaagaag aaaccaagag aaggaaaagg aaacacaacc tatttgtggg
781 agtttctttt agatctactt caagataaaa atacttgtcc caggtatatt aaatggactc
841 agagagaaaa aggcatattc aagctggtgg attcaaaggc tgtctctaag ctttggggaa
901 agcataagaa caaaccagac atgaactatg aaaccatggg acgagctttg agatactact
961 accaaagggg aattcttgca aaggttgaag gacagaggct tgtatatcag ttcaaggata
1021 tgccgaaaaa catagtggtc atagatgatg acaaaagtga aacctgtaat gaagatttag
1081 caggaactac tgatgaaaaa tcattagaac gagtgtcact gtctgcagaa agtctcctga
1141 aagcagcatc ctctgttcgc agtggaaaaa attcatcccc tataaactgc tccagagcag
1201 agaagggtgt agctagagtt gtgaatatca cttcccctgg gcacgatgct tcatccaggt
1261 ctcctactac cactgcatct gtgtcagcaa cagcagctcc aaggacagtt cgtgtggcaa
1321 tgcaggtacc tgttgtaatg acatcattgg gtcagaaaat ttcaactgtg gcagttcagt
1381 cagttaatgc aggtgcacca ttaataacca gcactagtcc aacaacagcg acctctccaa
1441 aggtagtcat tcagacaatc cctactgtga tgccagcttc tactgaaaat ggagacaaaa
1501 tcaccatgca gcctgccaaa attattacca tcccagctac acagcttgca cagtgtcaac
1561 tgcagacaaa gtcaaatctg actggatcag gaagcattaa cattgttgga accccattgg
1621 ctgtgagagc acttacccct gtttcaatag cccatggtac acctgtaatg agactatcaa
1681 tgcctactca gcaggcatct ggccagactc ctcctcgagt tatcagtgca gtcataaagg
1741 ggccagaggt taaatcggaa gcagtggcaa aaaagcaaga acatgatgtg aaaactttgc
1801 agctagtaga agaaaaacca gcagatggaa ataagacagt gacccacgta gtggttgtca
1861 gtgcgccttc agctattgcc cttcctgtaa ctatgaaaac agaaggacta gtgacatgtg
1921 agaaataaaa tagcagctcc accatggact tcaggctgtt agtggcagta ctgacataaa
1981 catttgcaag ggaagtcatc aagaaaagtc aaagaagact ttaaaacatt tttaatgcat
2041 atacaaaaac aatcagactt actggaaata aattacctat cccatgtttc agtgggaaat
2101 gaactacata ttgagatgct gacagaaaac tgcctcttac agtaggaaac aactgaaccc
2161 atcaataaga aaaaggatcg aaagggacca agcagctcac tacgatatca agttacacta
2221 agacttggaa cactaacatt ctgtaagagg ttatatagtt ttcagtggga ggggttggga
2281 tgggtaatct cattgttaca tatagcaatt tttgatgcat tttatatgca taccagcaat
2341 tattactgtg ttcgcacagt tctcacttaa ctggtgctat gtgaagactc tgctaatata
2401 ggtattttag aatgtgaatt gaagaatgga tcccaaaaac ttcagaaaga ggatagcaaa
2461 aaaagatcta gtgcgatttt atatatatat atatatatat atacatacat atatatatat
2521 catatagctt aagctgattt aaaacaaagg ccttagacta attttcgatt ttctttcttg
2581 aaataagcta atggcttgtt tgtgtaaagc ttttttatta aaagaaaaat tttaaaaaaa
2641 aaaaaaaaaa aaa
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