LOCUS AF254621 2232 bp mRNA linear HUM 09-MAY-2000
DEFINITION Homo sapiens NADPH oxidase 4 mRNA, complete cds.
ACCESSION AF254621
VERSION AF254621.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2232)
AUTHORS Cheng,G., Cao,Z. and Lambeth,J.D.
TITLE NADPH oxidase 4 (NOX4), a homolog of gp91phox and Mox1 (NOX1)
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2232)
AUTHORS Cheng,G., Cao,Z. and Lambeth,J.D.
TITLE Direct Submission
JOURNAL Submitted (10-APR-2000) Biochemistry, Emory University, 1510
Clifton Road, Atlanta, GA 30322, USA
FEATURES Location/Qualifiers
source 1..2232
/db_xref="H-InvDB:HIT000075121"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 87..1823
/note="NOX4; similar to Homo sapiens mitogenic oxidase
MOX1, and to the catalytic subunit gp91phox of the NADPH
oxidase of phagocytes"
/codon_start=1
/product="NADPH oxidase 4"
/protein_id="AAF68973.1"
/translation="MAVSWRSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYH
YLHQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSR
TFHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVP
GLTGVCMVVVLFLMITASTYAIRVSNYDIFWYTHNLFFVFYMLLTLHVSGGLLKYQTN
LDTHPPGCISLNRTSSQNISLPEYFSEHFHEPFPEGFSKPAEFTQHKFVKICMEEPRF
QANFPQTWLWISGPLCLYCAERLYRYIRSNKPVTIISVISHPSDVMEIRMVKENFKAR
PGQYITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPPSSQD
SEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWK
PYKLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENRPDYVNIQLYLSQTDGIQKII
GEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSY
GTRFEYNKESFS"
BASE COUNT 638 a 489 c 467 g 638 t
ORIGIN
1 ccgcacaact gtaaccgctg ccccggccgc cgcccgctcc ttctcgggcc ggcgggcaca
61 gagcgcagcg cggcggggcc ggcggcatgg ctgtgtcctg gaggagctgg ctcgccaacg
121 aaggggttaa acacctctgc ctgttcatct ggctctccat gaatgtcctg cttttctgga
181 aaaccttctt gctgtataac caagggccag agtatcacta cctccaccag atgttggggc
241 taggattgtg tctaagcaga gcctcagcat ctgttcttaa cctcaactgc agccttatcc
301 ttttacccat gtgccgaaca ctcttggctt acctccgagg atcacagaag gttccaagca
361 ggagaaccag gagattgttg gataaaagca gaacattcca tattacctgt ggtgttacta
421 tctgtatttt ctcaggcgtg catgtggctg cccatctggt gaatgccctc aacttctcag
481 tgaattacag tgaagacttt gttgaactga atgcagcaag ataccgagat gaggatccta
541 gaaaacttct cttcacaact gttcctggcc tgacaggggt ctgcatggtg gtggtgctat
601 tcctcatgat cacagcctct acatatgcaa taagagtttc taactatgat atcttctggt
661 atactcataa cctcttcttt gtcttctaca tgctgctgac gttgcatgtt tcaggagggc
721 tgctgaagta tcaaactaat ttagataccc accctcccgg ctgcatcagt cttaaccgaa
781 ccagctctca gaatatttcc ttaccagagt atttctcaga acattttcat gaacctttcc
841 ctgaaggatt ttcaaaaccg gcagagttta cccagcacaa atttgtgaag atttgtatgg
901 aagagcccag attccaagct aattttccac agacttggct ttggatttct ggacctttgt
961 gcctgtactg tgccgaaaga ctttacaggt atatccggag caataagcca gtcaccatca
1021 tttcggtcat aagtcatccc tcagatgtca tggaaatccg aatggtcaaa gaaaatttta
1081 aagcaagacc tggtcagtat attactctac attgtcccag tgtatctgca ttagaaaatc
1141 atccatttac cctcacaatg tgtccaactg aaaccaaagc aacatttggg gttcatctta
1201 aaatagtagg agactggaca gaacgatttc gagatttact actgcctcca tctagtcaag
1261 actccgaaat tctgcccttc attcaatcta gaaattatcc caagctgtat attgatggtc
1321 cttttggaag tccatttgag gaatcactga actatgaggt cagcctctgc gtggctggag
1381 gcattggagt aactccattt gcatcaatac tcaacaccct gttggatgac tggaaaccat
1441 acaagcttag aagactatac tttatttggg tatgcagaga tatccagtcc ttccgttggt
1501 ttgcagattt actctgtatg ttgcataaca agttttggca agagaacaga cctgactatg
1561 tcaacatcca gctgtacctc agtcaaacag atgggataca gaagataatt ggagaaaaat
1621 atcatgcact gaattcaaga ctgtttatag gacgtcctcg gtggaaactt ttgtttgatg
1681 aaatagcaaa atataacaga ggaaaaacag ttggtgtttt ctgttgtgga cccaattcac
1741 tatccaagac tcttcataaa ctgagtaacc agaacaactc atatgggaca agatttgaat
1801 acaataaaga gtctttcagc tgaaaacttt tgccatgaag caggactcta aagaaggaat
1861 gagtgcaatt tctaagactt tgaaactcag cggaatcaat cagctgtgtt atgccaaaga
1921 atagtaaggt tttcttattt atgattattt gaaaatggaa atgtgagaat gtggcaacat
1981 gaccgtcaca ttacatgttt aatctggaaa ccaaagagac cctgaagaat atttgatgtg
2041 atgattcatt ttcagttctc aaattaaaag aaaactgtta gatgcacact gttgattttc
2101 atggtggatt caagaactcc ctagtgagga gctgaacttg ctcaatctaa ggctgattgt
2161 cgtgttcctc tttaaattgt ttttggttga acaaatgcaa gattgaacaa aattaaaaat
2221 tcattgaagc tg
//